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Q5ZCI1 (MPK10_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mitogen-activated protein kinase 10

Short name=MAP kinase 10
EC=2.7.11.24
Gene names
Name:MPK10
Ordered Locus Names:Os01g0629900, LOC_Os01g43910
ORF Names:OSJNBb0035I14.5-1, OSJNBb0035I14.5-2, OSJNBb0035I14.5-3
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length611 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Enzyme regulation

Activated by threonine and tyrosine phosphorylation By similarity.

Domain

The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.

Post-translational modification

Dually phosphorylated on Thr-187 and Tyr-189, which activates the enzyme By similarity.

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

Contains 1 protein kinase domain.

Sequence caution

The sequence BAD61402.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence BAD61403.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Serine/threonine-protein kinase
Transferase
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processprotein autophosphorylation

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

MAP kinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 611611Mitogen-activated protein kinase 10
PRO_0000239753

Regions

Domain25 – 316292Protein kinase
Nucleotide binding31 – 399ATP By similarity
Motif187 – 1893TXY

Sites

Active site1511Proton acceptor By similarity
Binding site541ATP By similarity

Amino acid modifications

Modified residue1871Phosphothreonine By similarity
Modified residue1891Phosphotyrosine By similarity

Experimental info

Sequence conflict1531K → R Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q5ZCI1 [UniParc].

Last modified June 13, 2006. Version 2.
Checksum: 790BC90D262BEFCD

FASTA61169,400
        10         20         30         40         50         60 
MQQDQRKKSS TEADFFTEYG DASRYKIQEV IGKGSYGVVC SAIDVHTGEK VAIKKIHDIF 

        70         80         90        100        110        120 
EHISDAARIL REIKLLRLLR HPDIVEIKHI MLPPSRRDFK DIYVVFELME SDLHQVIKAN 

       130        140        150        160        170        180 
DDLTKEHYQF FLYQLLRALK YIHTANVYHR DLKPKNILAN SNCKLKICDF GLARVAFNDT 

       190        200        210        220        230        240 
PTTIFWTDYV ATRWYRAPEL CGSFFSKYTP AIDIWSIGCI FAEVLTGKPL FPGKNVVHQL 

       250        260        270        280        290        300 
DLMTDLLGTP SMDTISRVRN DKARRYLSSM RKKEPILFSQ KFPSADPLAL DLLQKLLAFD 

       310        320        330        340        350        360 
PKDRPTAEEA LAHPYFKGLA KVEREPSCQP ITKMEFEFER RRVTKEDIRE LIFREILEYH 

       370        380        390        400        410        420 
PQLLKDYING TERTTFLYPS AVDQFRKQFA HLEENGGNGP VIPMDRKHTS LPRSTIVHST 

       430        440        450        460        470        480 
PIPAKEQPRI GPSRDKPSDE PYSNPREFDR FSGNAPRTSQ APQRVPTARP GRVVGPVLPY 

       490        500        510        520        530        540 
ENGATKDSYD ARRLAMNSGY PPQQQIPQAY GYYQIPGKSA CSELSQAERY TLHQQAYTCA 

       550        560        570        580        590        600 
NSATVTDVAL DMRAPPFHLS GGPKSDSSER LAAETNLYTR SLNGLAATAA GVAASAHRKV 

       610 
GVVPYGMSRM Y 

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence and structure of rice chromosome 1."
Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M. expand/collapse author list , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.
Nature 420:312-316(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.
[3]"Molecular analysis of the rice MAP kinase gene family in relation to Magnaporthe grisea infection."
Reyna N.S., Yang Y.
Mol. Plant Microbe Interact. 19:530-540(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP003220 Genomic DNA. Translation: BAD61401.1.
AP003220 Genomic DNA. Translation: BAD61402.1. Sequence problems.
AP003220 Genomic DNA. Translation: BAD61403.1. Sequence problems.
AK065930 mRNA. No translation available.
RefSeqNP_001043642.1. NM_001050177.1.
UniGeneOs.26152.

3D structure databases

ProteinModelPortalQ5ZCI1.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ5ZCI1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS01T0629900-01; OS01T0629900-01; OS01G0629900.
GeneID4326668.
KEGGosa:4326668.

Organism-specific databases

GrameneQ5ZCI1.

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000233024.
OMASQAERYT.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMPK10_ORYSJ
AccessionPrimary (citable) accession number: Q5ZCI1
Secondary accession number(s): Q5ZCI2, Q5ZCI3
Entry history
Integrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: June 13, 2006
Last modified: May 14, 2014
This is version 57 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations