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Q5ZCI1

- MPK10_ORYSJ

UniProt

Q5ZCI1 - MPK10_ORYSJ

Protein

Mitogen-activated protein kinase 10

Gene

MPK10

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 2 (13 Jun 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Enzyme regulationi

    Activated by threonine and tyrosine phosphorylation.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei54 – 541ATPPROSITE-ProRule annotation
    Active sitei151 – 1511Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi31 – 399ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. MAP kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. protein autophosphorylation Source: EnsemblPlants/Gramene

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Mitogen-activated protein kinase 10 (EC:2.7.11.24)
    Short name:
    MAP kinase 10
    Gene namesi
    Name:MPK10
    Ordered Locus Names:Os01g0629900, LOC_Os01g43910
    ORF Names:OSJNBb0035I14.5-1, OSJNBb0035I14.5-2, OSJNBb0035I14.5-3
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 1

    Organism-specific databases

    GrameneiQ5ZCI1.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 611611Mitogen-activated protein kinase 10PRO_0000239753Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei187 – 1871PhosphothreonineBy similarity
    Modified residuei189 – 1891PhosphotyrosineBy similarity

    Post-translational modificationi

    Dually phosphorylated on Thr-187 and Tyr-189, which activates the enzyme.By similarity

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PRIDEiQ5ZCI1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5ZCI1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini25 – 316292Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi187 – 1893TXY

    Domaini

    The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.

    Sequence similaritiesi

    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    HOGENOMiHOG000233024.
    OMAiSQAERYT.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR003527. MAP_kinase_CS.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS01351. MAPK. 1 hit.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5ZCI1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQQDQRKKSS TEADFFTEYG DASRYKIQEV IGKGSYGVVC SAIDVHTGEK    50
    VAIKKIHDIF EHISDAARIL REIKLLRLLR HPDIVEIKHI MLPPSRRDFK 100
    DIYVVFELME SDLHQVIKAN DDLTKEHYQF FLYQLLRALK YIHTANVYHR 150
    DLKPKNILAN SNCKLKICDF GLARVAFNDT PTTIFWTDYV ATRWYRAPEL 200
    CGSFFSKYTP AIDIWSIGCI FAEVLTGKPL FPGKNVVHQL DLMTDLLGTP 250
    SMDTISRVRN DKARRYLSSM RKKEPILFSQ KFPSADPLAL DLLQKLLAFD 300
    PKDRPTAEEA LAHPYFKGLA KVEREPSCQP ITKMEFEFER RRVTKEDIRE 350
    LIFREILEYH PQLLKDYING TERTTFLYPS AVDQFRKQFA HLEENGGNGP 400
    VIPMDRKHTS LPRSTIVHST PIPAKEQPRI GPSRDKPSDE PYSNPREFDR 450
    FSGNAPRTSQ APQRVPTARP GRVVGPVLPY ENGATKDSYD ARRLAMNSGY 500
    PPQQQIPQAY GYYQIPGKSA CSELSQAERY TLHQQAYTCA NSATVTDVAL 550
    DMRAPPFHLS GGPKSDSSER LAAETNLYTR SLNGLAATAA GVAASAHRKV 600
    GVVPYGMSRM Y 611
    Length:611
    Mass (Da):69,400
    Last modified:June 13, 2006 - v2
    Checksum:i790BC90D262BEFCD
    GO

    Sequence cautioni

    The sequence BAD61402.1 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence BAD61403.1 differs from that shown. Reason: Erroneous gene model prediction.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti153 – 1531K → R(PubMed:12869764)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP003220 Genomic DNA. Translation: BAD61401.1.
    AP003220 Genomic DNA. Translation: BAD61402.1. Sequence problems.
    AP003220 Genomic DNA. Translation: BAD61403.1. Sequence problems.
    AK065930 mRNA. No translation available.
    RefSeqiNP_001043642.1. NM_001050177.1.
    UniGeneiOs.26152.

    Genome annotation databases

    EnsemblPlantsiOS01T0629900-01; OS01T0629900-01; OS01G0629900.
    GeneIDi4326668.
    KEGGiosa:4326668.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP003220 Genomic DNA. Translation: BAD61401.1 .
    AP003220 Genomic DNA. Translation: BAD61402.1 . Sequence problems.
    AP003220 Genomic DNA. Translation: BAD61403.1 . Sequence problems.
    AK065930 mRNA. No translation available.
    RefSeqi NP_001043642.1. NM_001050177.1.
    UniGenei Os.26152.

    3D structure databases

    ProteinModelPortali Q5ZCI1.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q5ZCI1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS01T0629900-01 ; OS01T0629900-01 ; OS01G0629900 .
    GeneIDi 4326668.
    KEGGi osa:4326668.

    Organism-specific databases

    Gramenei Q5ZCI1.

    Phylogenomic databases

    eggNOGi COG0515.
    HOGENOMi HOG000233024.
    OMAi SQAERYT.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR003527. MAP_kinase_CS.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS01351. MAPK. 1 hit.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence and structure of rice chromosome 1."
      Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.
      , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.
      Nature 420:312-316(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
      The rice full-length cDNA consortium
      Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Nipponbare.
    3. "Molecular analysis of the rice MAP kinase gene family in relation to Magnaporthe grisea infection."
      Reyna N.S., Yang Y.
      Mol. Plant Microbe Interact. 19:530-540(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NOMENCLATURE.

    Entry informationi

    Entry nameiMPK10_ORYSJ
    AccessioniPrimary (citable) accession number: Q5ZCI1
    Secondary accession number(s): Q5ZCI2, Q5ZCI3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 13, 2006
    Last sequence update: June 13, 2006
    Last modified: October 1, 2014
    This is version 58 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3