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Q5Z8V7

- HACL2_ORYSJ

UniProt

Q5Z8V7 - HACL2_ORYSJ

Protein

Probable histone acetyltransferase HAC-like 2

Gene

Os06g0704800

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 2 (09 Jan 2007)
      Previous versions | rss
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    Functioni

    Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation By similarity.By similarity

    Catalytic activityi

    Acetyl-CoA + [histone] = CoA + acetyl-[histone].

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri607 – 68781TAZ-typePROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri827 – 933107PHD-type; degenerateAdd
    BLAST
    Zinc fingeri1264 – 131148ZZ-typePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. histone acetyltransferase activity Source: UniProtKB-EC
    2. transcription cofactor activity Source: InterPro
    3. zinc ion binding Source: InterPro

    GO - Biological processi

    1. flower development Source: EnsemblPlants/Gramene
    2. regulation of transcription, DNA-templated Source: UniProtKB-KW
    3. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Activator, Acyltransferase, Chromatin regulator, Transferase

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable histone acetyltransferase HAC-like 2 (EC:2.3.1.48)
    Gene namesi
    Ordered Locus Names:Os06g0704800, LOC_Os06g49130
    ORF Names:P0018H04.4
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 6

    Organism-specific databases

    GrameneiQ5Z8V7.

    Subcellular locationi

    Nucleus Curated

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 14391439Probable histone acetyltransferase HAC-like 2PRO_0000269746Add
    BLAST

    Proteomic databases

    PRIDEiQ5Z8V7.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5Z8V7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili964 – 98926Sequence AnalysisAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi132 – 1354Poly-Ser
    Compositional biasi379 – 43557Gln-richAdd
    BLAST

    Sequence similaritiesi

    Contains 1 PHD-type zinc finger.Curated
    Contains 1 TAZ-type zinc finger.PROSITE-ProRule annotation
    Contains 1 ZZ-type zinc finger.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri607 – 68781TAZ-typePROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri827 – 933107PHD-type; degenerateAdd
    BLAST
    Zinc fingeri1264 – 131148ZZ-typePROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Coiled coil, Zinc-finger

    Phylogenomic databases

    eggNOGiNOG326839.
    HOGENOMiHOG000242057.
    KOiK04498.

    Family and domain databases

    Gene3Di1.20.1020.10. 1 hit.
    3.30.40.10. 1 hit.
    InterProiIPR013178. Histone_H3-K56_AcTrfase_RTT109.
    IPR011011. Znf_FYVE_PHD.
    IPR013083. Znf_RING/FYVE/PHD.
    IPR000197. Znf_TAZ.
    IPR000433. Znf_ZZ.
    [Graphical view]
    PfamiPF08214. KAT11. 1 hit.
    PF02135. zf-TAZ. 1 hit.
    [Graphical view]
    SMARTiSM00291. ZnF_ZZ. 1 hit.
    [Graphical view]
    SUPFAMiSSF57903. SSF57903. 1 hit.
    SSF57933. SSF57933. 1 hit.
    PROSITEiPS50134. ZF_TAZ. 1 hit.
    PS01357. ZF_ZZ_1. 1 hit.
    PS50135. ZF_ZZ_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5Z8V7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKQGQGAHLS GQRIGHHPTA QMNPGDGDGN GRHQVASGHA SADPELMNLR     50
    IRMTNRLIWE LLSREPKLQT RPRKLVSDLA KRFEAVIYKK NPNKAAYYSI 100
    LNGEIFPHLQ HALSTHMAQH QQGQQMLQQL TSSSSYGTTI PIPDVVQNAS 150
    GNTRALYEMD NTSGPMSNGH HHFSANFPLH STTKGASLEM SAVSMQEGKI 200
    THMIPTPGSS NQQSLPGNFH YSTGTGYLNG KSNVMAQMQE QQAPFASKIN 250
    CCPVQRDLGG YAGSGVHSDI LNNSSPYGVS EAHMIDGMGL HRSNVQVINR 300
    TVVPETFINP SPYGISPNKP LQRHVNPSTR STPTPADIAA STSFNGTGSS 350
    ALSTTSYLDM TTVNSLPKSR MDSGLIMSQP TIQSFQTEYY IQTEGLDLQE 400
    KISLEQLHQQ VNQLHLIQPH SQYAQNQCSL KLQQQNSLHH LVMSRGNVLT 450
    QCHLGSDHAE KLLDKRNQLH SELVSSQINE HVGLTNLQGH YEQTQYHDNY 500
    KKGQMSASSQ NLGIPAPHDL LPPQQQFDDG SYRLSCFLKE TYTKPLQPHC 550
    KSKPMKEVIM TSLLSGKIQD GFCQKKMARD REHHPIISGW HSAGCAATSF 600
    GSEEVMENTK QYHAQARWLL FLFHAKSCTS PPGSCKSSYC DRVRELVVHL 650
    TDCQIKDCSY RHCRESKMVS DHYKNCINEH CHVCCKAKEM LRRSSELAHK 700
    QNPAEPILIT QHNMNQRSAD RVHGDRMDID QAVETFDDQP PAAKRPKLQL 750
    VSPDASENVP VCQKNPGFML QEAHPRQLDQ NKKMVPDQEV DVGLDIRHPQ 800
    VTLVSCHGSD EKIGAAQNTV IPGALNKIHC HVQQETVVAD KESVTVVDVK 850
    KKTGSVDVTI SKTGKPKVKG VSLMELFTPE QIHEHINSLR QWIGQWVQCD 900
    KCECWQHQIC ALFNARRNDV EEAEYTCFKC YIEEFKRGLR MPLPESVVRG 950
    AKDLPRTLLS DHIEERLFKR LREERQERAN KLKTSLDEVP GADGLVVRVV 1000
    SSVDKKLEVK PHFFKILQED NYPAEFPYKS KAILLFQKIE GVEVCLFGMY 1050
    VQEYGAECKF PNQRRVYLSY LDSVKYFRPD IETVSGQALR TYVYHEILIG 1100
    YLEYYKQRGF TSCYIWACPP VKGEDYILYC HPEIQKTPKS DKLRQWYLSM 1150
    LQKAIKENIV VELTNLYDQF FVTAKECKIK VSAARLPYFD GDYWPGAAED 1200
    IINQLQLEGD GKLLKKGRVN KIITKRALKA AGHTDLSGNA SKEAMLMQKL 1250
    GEIICPIKDD LIMVHLQYSC SHCCTFMVSG RRWVCNECKS FYICDRCYNA 1300
    EQRLEEKERH PSNSKCLHIL HPVEIVGVSE DTKDRDIILE NEIFDTRQAF 1350
    LSFCQGYHYQ YDTLRRAKHS TMMMLYHLHN PTGPAFVATC NVCNCDIENG 1400
    QGWDFKSFER KQNQLSESRR MASVNERVRQ RVAEVTRHE 1439
    Length:1,439
    Mass (Da):163,087
    Last modified:January 9, 2007 - v2
    Checksum:i35E3EA99C1F6AFF7
    GO

    Sequence cautioni

    The sequence BAD53797.1 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence BAF20426.2 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP003761 Genomic DNA. Translation: BAD53797.1. Sequence problems.
    AP008212 Genomic DNA. Translation: BAF20426.2. Sequence problems.
    RefSeqiNP_001058512.2. NM_001065047.2.
    UniGeneiOs.80423.

    Genome annotation databases

    EnsemblPlantsiOS06T0704800-00; OS06T0704800-00; OS06G0704800.
    GeneIDi4341999.
    KEGGiosa:4341999.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP003761 Genomic DNA. Translation: BAD53797.1 . Sequence problems.
    AP008212 Genomic DNA. Translation: BAF20426.2 . Sequence problems.
    RefSeqi NP_001058512.2. NM_001065047.2.
    UniGenei Os.80423.

    3D structure databases

    ProteinModelPortali Q5Z8V7.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q5Z8V7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS06T0704800-00 ; OS06T0704800-00 ; OS06G0704800 .
    GeneIDi 4341999.
    KEGGi osa:4341999.

    Organism-specific databases

    Gramenei Q5Z8V7.

    Phylogenomic databases

    eggNOGi NOG326839.
    HOGENOMi HOG000242057.
    KOi K04498.

    Family and domain databases

    Gene3Di 1.20.1020.10. 1 hit.
    3.30.40.10. 1 hit.
    InterProi IPR013178. Histone_H3-K56_AcTrfase_RTT109.
    IPR011011. Znf_FYVE_PHD.
    IPR013083. Znf_RING/FYVE/PHD.
    IPR000197. Znf_TAZ.
    IPR000433. Znf_ZZ.
    [Graphical view ]
    Pfami PF08214. KAT11. 1 hit.
    PF02135. zf-TAZ. 1 hit.
    [Graphical view ]
    SMARTi SM00291. ZnF_ZZ. 1 hit.
    [Graphical view ]
    SUPFAMi SSF57903. SSF57903. 1 hit.
    SSF57933. SSF57933. 1 hit.
    PROSITEi PS50134. ZF_TAZ. 1 hit.
    PS01357. ZF_ZZ_1. 1 hit.
    PS50135. ZF_ZZ_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. "The rice annotation project database (RAP-DB): 2008 update."
      The rice annotation project (RAP)
      Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: cv. Nipponbare.

    Entry informationi

    Entry nameiHACL2_ORYSJ
    AccessioniPrimary (citable) accession number: Q5Z8V7
    Secondary accession number(s): Q0D9P7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 9, 2007
    Last sequence update: January 9, 2007
    Last modified: October 1, 2014
    This is version 66 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3