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Q5Z8T3

- MIOX_ORYSJ

UniProt

Q5Z8T3 - MIOX_ORYSJ

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Protein
Probable inositol oxygenase
Gene
Os06g0561000, LOC_Os06g36560, P0456F09.5, P0528E12.30
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Involved in the biosynthesis of UDP-glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell-wall polymers. May be also involved in plant ascorbate biosynthesis By similarity.

Catalytic activityi

Myo-inositol + O2 = D-glucuronate + H2O.

Cofactori

Binds 2 iron ions per subunit By similarity.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei49 – 491Substrate By similarity
Metal bindingi119 – 1191Iron 1 By similarity
Metal bindingi144 – 1441Iron 1 By similarity
Metal bindingi145 – 1451Iron 1 By similarity
Metal bindingi145 – 1451Iron 2 By similarity
Binding sitei148 – 1481Substrate By similarity
Metal bindingi217 – 2171Iron 2 By similarity
Metal bindingi243 – 2431Iron 2 By similarity
Metal bindingi276 – 2761Iron 1 By similarity

GO - Molecular functioni

  1. inositol oxygenase activity Source: UniProtKB-EC
  2. iron ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. L-ascorbic acid biosynthetic process Source: UniProtKB-KW
  2. inositol catabolic process Source: InterPro
  3. syncytium formation Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Ascorbate biosynthesis

Keywords - Ligandi

Iron, Metal-binding

Enzyme and pathway databases

UniPathwayiUPA00111; UER00527.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable inositol oxygenase (EC:1.13.99.1)
Alternative name(s):
Myo-inositol oxygenase
Short name:
MI oxygenase
Gene namesi
Ordered Locus Names:Os06g0561000, LOC_Os06g36560
ORF Names:P0456F09.5, P0528E12.30
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 6

Organism-specific databases

GrameneiQ5Z8T3.

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 308308Probable inositol oxygenase
PRO_0000079158Add
BLAST

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni106 – 1083Substrate binding By similarity
Regioni165 – 1662Substrate binding By similarity
Regioni243 – 2442Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiNOG135479.
KOiK00469.
OMAiNFYREQH.

Family and domain databases

InterProiIPR007828. Inositol_oxygenase.
[Graphical view]
PANTHERiPTHR12588. PTHR12588. 1 hit.
PfamiPF05153. DUF706. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5Z8T3-1 [UniParc]FASTAAdd to Basket

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MTITIEQPHL DAIADRKVAG GGGGDNAAEL VLDGGFVVPD SNAFGNAFRN    50
YEAESERKET VEEFYRVNHI NQTYDFVRRM REEYGRVDKT EMGIWECIEL 100
LNEFIDDSDP DLDMPQIEHL LQTAEAIRKD FPDEDWLHLT GLIHDLGKVL 150
LHPSFGELPQ WSVVGDTFPV GCAFDECNVH FKYFKENPDY LNPKLNTKFG 200
AYSEGCGLDN VLMSWGHDDY MYLVAKENKT TLPSAGLFII RYHSFYPLHK 250
HGAYMHLMND EDKENLKWLR VFNKYDLYSK SNERIDVEKV KPYYMSLIEK 300
YFPAKLRW 308
Length:308
Mass (Da):35,805
Last modified:November 23, 2004 - v1
Checksum:i7612DA5BFA7DE5FF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP003713 Genomic DNA. Translation: BAD53740.1.
AP003762 Genomic DNA. Translation: BAD53821.1.
AK068862 mRNA. No translation available.
RefSeqiNP_001057871.1. NM_001064406.1.
UniGeneiOs.6345.

Genome annotation databases

EnsemblPlantsiOS06T0561000-01; OS06T0561000-01; OS06G0561000.
GeneIDi4341305.
KEGGiosa:4341305.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP003713 Genomic DNA. Translation: BAD53740.1 .
AP003762 Genomic DNA. Translation: BAD53821.1 .
AK068862 mRNA. No translation available.
RefSeqi NP_001057871.1. NM_001064406.1.
UniGenei Os.6345.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS06T0561000-01 ; OS06T0561000-01 ; OS06G0561000 .
GeneIDi 4341305.
KEGGi osa:4341305.

Organism-specific databases

Gramenei Q5Z8T3.

Phylogenomic databases

eggNOGi NOG135479.
KOi K00469.
OMAi NFYREQH.

Enzyme and pathway databases

UniPathwayi UPA00111 ; UER00527 .

Family and domain databases

InterProi IPR007828. Inositol_oxygenase.
[Graphical view ]
PANTHERi PTHR12588. PTHR12588. 1 hit.
Pfami PF05153. DUF706. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiMIOX_ORYSJ
AccessioniPrimary (citable) accession number: Q5Z8T3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: November 23, 2004
Last modified: May 14, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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