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Protein

Cyclin-dependent kinase F-1

Gene

CDKF-1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.
ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei53ATPPROSITE-ProRule annotation1
Active sitei146Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi30 – 38ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinase F-1 (EC:2.7.11.22, EC:2.7.11.23)
Short name:
CDKF;1
Gene namesi
Name:CDKF-1
Ordered Locus Names:Os06g0334400, LOC_Os06g22820
ORF Names:OSJNBa0012F14.17
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 6

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002961051 – 479Cyclin-dependent kinase F-1Add BLAST479

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei291PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ5Z754.
PRIDEiQ5Z754.

PTM databases

iPTMnetiQ5Z754.

Expressioni

Inductioni

By auxin. Down-regulated by cytokinin.1 Publication

Gene expression databases

ExpressionAtlasiQ5Z754. baseline and differential.
GenevisibleiQ5Z754. OS.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os06g22820.1.

Structurei

3D structure databases

ProteinModelPortaliQ5Z754.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 419Protein kinasePROSITE-ProRule annotationAdd BLAST396

Sequence similaritiesi

Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0594. Eukaryota.
ENOG410XPP3. LUCA.
InParanoidiQ5Z754.
OMAiARILMEP.
OrthoDBiEOG09360A7L.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 2 hits.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 2 hits.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5Z754-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIGGGGGGG SWSIHGRPDV TSRYEVLGRA GSGAYADVYR GRRRSDGAPV
60 70 80 90 100
ALKEVHDAVS ARREADALLA AAPSRHVVAL LDHFPGGDHD DDVLVLEWLP
110 120 130 140 150
LDLSAVVRAA AAARPSALPA AQRKRWMLQV LEGVAACHSA GVVHRDLKPA
160 170 180 190 200
NLLISEDGVL KVADLGQARI LQETGTYQGM HPYEQSSGVE PWVSQQRAVL
210 220 230 240 250
HGVKENHPSH DSETQTGQEP ERLTAADYLH EMDQLRAKST HGDVDKMSLQ
260 270 280 290 300
DGNASCLATC STADIDDDPF RASYSYDAEE GMLEEESGAF TSCVGTRWFR
310 320 330 340 350
APELLYGSTN YGQEVDLWSL GCILAELFNL EPIFPGTSDI DQIGRIISVL
360 370 380 390 400
GNITEETFPG CSNLPDYNKI FFNKVEKPIG LEACLPDRSA SEVSIIKRLL
410 420 430 440 450
CYDPTKRASA ADLLNDPYFA EEPLPVPIEG LQVPESKDED DDSTEEWANF
460 470
RGGDSDSDFD EFGSMDVTKT DKGFSIRFS
Length:479
Mass (Da):52,073
Last modified:November 23, 2004 - v1
Checksum:i0FA906213F770759
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti253N → D in AK120969 (PubMed:12869764).Curated1
Sequence conflicti394S → G in AK120969 (PubMed:12869764).Curated1
Sequence conflicti450F → L in AK120969 (PubMed:12869764).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004784 Genomic DNA. Translation: BAD61885.1.
AP008212 Genomic DNA. Translation: BAF19465.1.
AP014962 Genomic DNA. Translation: BAS97580.1.
AK120969 mRNA. No translation available.
RefSeqiXP_015644444.1. XM_015788958.1.
UniGeneiOs.11911.

Genome annotation databases

EnsemblPlantsiOS06T0334400-01; OS06T0334400-01; OS06G0334400.
GeneIDi4340934.
GrameneiOS06T0334400-01; OS06T0334400-01; OS06G0334400.
KEGGiosa:4340934.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004784 Genomic DNA. Translation: BAD61885.1.
AP008212 Genomic DNA. Translation: BAF19465.1.
AP014962 Genomic DNA. Translation: BAS97580.1.
AK120969 mRNA. No translation available.
RefSeqiXP_015644444.1. XM_015788958.1.
UniGeneiOs.11911.

3D structure databases

ProteinModelPortaliQ5Z754.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os06g22820.1.

PTM databases

iPTMnetiQ5Z754.

Proteomic databases

PaxDbiQ5Z754.
PRIDEiQ5Z754.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS06T0334400-01; OS06T0334400-01; OS06G0334400.
GeneIDi4340934.
GrameneiOS06T0334400-01; OS06T0334400-01; OS06G0334400.
KEGGiosa:4340934.

Phylogenomic databases

eggNOGiKOG0594. Eukaryota.
ENOG410XPP3. LUCA.
InParanoidiQ5Z754.
OMAiARILMEP.
OrthoDBiEOG09360A7L.

Gene expression databases

ExpressionAtlasiQ5Z754. baseline and differential.
GenevisibleiQ5Z754. OS.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 2 hits.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 2 hits.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCDKF1_ORYSJ
AccessioniPrimary (citable) accession number: Q5Z754
Secondary accession number(s): A0A0P0WWF8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: November 23, 2004
Last modified: November 2, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.