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Protein

Cyclin-dependent kinase F-1

Gene

CDKF-1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.
ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei53ATPPROSITE-ProRule annotation1
Active sitei146Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi30 – 38ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinase F-1 (EC:2.7.11.22, EC:2.7.11.23)
Short name:
CDKF;1
Gene namesi
Name:CDKF-1
Ordered Locus Names:Os06g0334400, LOC_Os06g22820
ORF Names:OSJNBa0012F14.17
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002961051 – 479Cyclin-dependent kinase F-1Add BLAST479

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei291PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ5Z754

PTM databases

iPTMnetiQ5Z754

Expressioni

Inductioni

By auxin. Down-regulated by cytokinin.1 Publication

Gene expression databases

ExpressionAtlasiQ5Z754 differential
GenevisibleiQ5Z754 OS

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os06g22820.1

Structurei

3D structure databases

ProteinModelPortaliQ5Z754
SMRiQ5Z754
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 419Protein kinasePROSITE-ProRule annotationAdd BLAST396

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0594 Eukaryota
ENOG410XPP3 LUCA
InParanoidiQ5Z754
OMAiARILMEP
OrthoDBiEOG09360A7L

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 2 hits
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 2 hits
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

Q5Z754-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIGGGGGGG SWSIHGRPDV TSRYEVLGRA GSGAYADVYR GRRRSDGAPV
60 70 80 90 100
ALKEVHDAVS ARREADALLA AAPSRHVVAL LDHFPGGDHD DDVLVLEWLP
110 120 130 140 150
LDLSAVVRAA AAARPSALPA AQRKRWMLQV LEGVAACHSA GVVHRDLKPA
160 170 180 190 200
NLLISEDGVL KVADLGQARI LQETGTYQGM HPYEQSSGVE PWVSQQRAVL
210 220 230 240 250
HGVKENHPSH DSETQTGQEP ERLTAADYLH EMDQLRAKST HGDVDKMSLQ
260 270 280 290 300
DGNASCLATC STADIDDDPF RASYSYDAEE GMLEEESGAF TSCVGTRWFR
310 320 330 340 350
APELLYGSTN YGQEVDLWSL GCILAELFNL EPIFPGTSDI DQIGRIISVL
360 370 380 390 400
GNITEETFPG CSNLPDYNKI FFNKVEKPIG LEACLPDRSA SEVSIIKRLL
410 420 430 440 450
CYDPTKRASA ADLLNDPYFA EEPLPVPIEG LQVPESKDED DDSTEEWANF
460 470
RGGDSDSDFD EFGSMDVTKT DKGFSIRFS
Length:479
Mass (Da):52,073
Last modified:November 23, 2004 - v1
Checksum:i0FA906213F770759
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti253N → D in AK120969 (PubMed:12869764).Curated1
Sequence conflicti394S → G in AK120969 (PubMed:12869764).Curated1
Sequence conflicti450F → L in AK120969 (PubMed:12869764).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004784 Genomic DNA Translation: BAD61885.1
AP008212 Genomic DNA Translation: BAF19465.1
AP014962 Genomic DNA Translation: BAS97580.1
AK120969 mRNA No translation available.
RefSeqiXP_015644444.1, XM_015788958.1
UniGeneiOs.11911

Genome annotation databases

EnsemblPlantsiOs06t0334400-01; Os06t0334400-01; Os06g0334400
GeneIDi4340934
GrameneiOs06t0334400-01; Os06t0334400-01; Os06g0334400
KEGGiosa:4340934

Similar proteinsi

Entry informationi

Entry nameiCDKF1_ORYSJ
AccessioniPrimary (citable) accession number: Q5Z754
Secondary accession number(s): A0A0P0WWF8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: November 23, 2004
Last modified: May 23, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health