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Q5Z754

- CDKF1_ORYSJ

UniProt

Q5Z754 - CDKF1_ORYSJ

Protein

Cyclin-dependent kinase F-1

Gene

CDKF-1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 1 (23 Nov 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.
    ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei53 – 531ATPPROSITE-ProRule annotation
    Active sitei146 – 1461Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi30 – 389ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. cyclin-dependent protein kinase activating kinase activity Source: EnsemblPlants/Gramene
    3. cyclin-dependent protein serine/threonine kinase activity Source: UniProtKB-EC
    4. RNA polymerase II carboxy-terminal domain kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. maintenance of root meristem identity Source: EnsemblPlants/Gramene

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cyclin-dependent kinase F-1 (EC:2.7.11.22, EC:2.7.11.23)
    Short name:
    CDKF;1
    Gene namesi
    Name:CDKF-1
    Ordered Locus Names:Os06g0334400, LOC_Os06g22820
    ORF Names:OSJNBa0012F14.17
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 6

    Organism-specific databases

    GrameneiQ5Z754.

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: EnsemblPlants/Gramene
    2. nucleus Source: EnsemblPlants/Gramene

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 479479Cyclin-dependent kinase F-1PRO_0000296105Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei291 – 2911PhosphothreonineBy similarity

    Keywords - PTMi

    Phosphoprotein

    Expressioni

    Inductioni

    By auxin. Down-regulated by cytokinin.1 Publication

    Structurei

    3D structure databases

    ProteinModelPortaliQ5Z754.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini24 – 419396Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    OMAiTEEWANF.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 2 hits.
    [Graphical view]
    SMARTiSM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 2 hits.
    PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5Z754-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAIGGGGGGG SWSIHGRPDV TSRYEVLGRA GSGAYADVYR GRRRSDGAPV    50
    ALKEVHDAVS ARREADALLA AAPSRHVVAL LDHFPGGDHD DDVLVLEWLP 100
    LDLSAVVRAA AAARPSALPA AQRKRWMLQV LEGVAACHSA GVVHRDLKPA 150
    NLLISEDGVL KVADLGQARI LQETGTYQGM HPYEQSSGVE PWVSQQRAVL 200
    HGVKENHPSH DSETQTGQEP ERLTAADYLH EMDQLRAKST HGDVDKMSLQ 250
    DGNASCLATC STADIDDDPF RASYSYDAEE GMLEEESGAF TSCVGTRWFR 300
    APELLYGSTN YGQEVDLWSL GCILAELFNL EPIFPGTSDI DQIGRIISVL 350
    GNITEETFPG CSNLPDYNKI FFNKVEKPIG LEACLPDRSA SEVSIIKRLL 400
    CYDPTKRASA ADLLNDPYFA EEPLPVPIEG LQVPESKDED DDSTEEWANF 450
    RGGDSDSDFD EFGSMDVTKT DKGFSIRFS 479
    Length:479
    Mass (Da):52,073
    Last modified:November 23, 2004 - v1
    Checksum:i0FA906213F770759
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti253 – 2531N → D in AK120969. (PubMed:12869764)Curated
    Sequence conflicti394 – 3941S → G in AK120969. (PubMed:12869764)Curated
    Sequence conflicti450 – 4501F → L in AK120969. (PubMed:12869764)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP004784 Genomic DNA. Translation: BAD61885.1.
    AP008212 Genomic DNA. Translation: BAF19465.1.
    AK120969 mRNA. No translation available.
    RefSeqiNP_001057551.1. NM_001064086.1.
    UniGeneiOs.11911.

    Genome annotation databases

    EnsemblPlantsiOS06T0334400-01; OS06T0334400-01; OS06G0334400.
    GeneIDi4340934.
    KEGGiosa:4340934.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP004784 Genomic DNA. Translation: BAD61885.1 .
    AP008212 Genomic DNA. Translation: BAF19465.1 .
    AK120969 mRNA. No translation available.
    RefSeqi NP_001057551.1. NM_001064086.1.
    UniGenei Os.11911.

    3D structure databases

    ProteinModelPortali Q5Z754.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS06T0334400-01 ; OS06T0334400-01 ; OS06G0334400 .
    GeneIDi 4340934.
    KEGGi osa:4340934.

    Organism-specific databases

    Gramenei Q5Z754.

    Phylogenomic databases

    eggNOGi COG0515.
    OMAi TEEWANF.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 2 hits.
    [Graphical view ]
    SMARTi SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 2 hits.
    PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. "The rice annotation project database (RAP-DB): 2008 update."
      The rice annotation project (RAP)
      Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: cv. Nipponbare.
    3. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
      The rice full-length cDNA consortium
      Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Nipponbare.
    4. "Genome-wide identification and expression analysis of rice cell cycle genes."
      Guo J., Song J., Wang F., Zhang X.S.
      Plant Mol. Biol. 64:349-360(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: INDUCTION, GENE FAMILY.

    Entry informationi

    Entry nameiCDKF1_ORYSJ
    AccessioniPrimary (citable) accession number: Q5Z754
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 24, 2007
    Last sequence update: November 23, 2004
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3