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Q5Z754

- CDKF1_ORYSJ

UniProt

Q5Z754 - CDKF1_ORYSJ

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Protein

Cyclin-dependent kinase F-1

Gene

CDKF-1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.
ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei53 – 531ATPPROSITE-ProRule annotation
Active sitei146 – 1461Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi30 – 389ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. cyclin-dependent protein kinase activating kinase activity Source: EnsemblPlants/Gramene
  3. cyclin-dependent protein serine/threonine kinase activity Source: UniProtKB-EC
  4. RNA polymerase II carboxy-terminal domain kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. cell division Source: EnsemblPlants/Gramene
  2. DNA endoreduplication Source: EnsemblPlants/Gramene
  3. maintenance of root meristem identity Source: EnsemblPlants/Gramene
  4. mitotic cell cycle Source: EnsemblPlants/Gramene
  5. negative regulation of cyclin-dependent protein serine/threonine kinase activity Source: EnsemblPlants/Gramene
  6. stomatal lineage progression Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinase F-1 (EC:2.7.11.22, EC:2.7.11.23)
Short name:
CDKF;1
Gene namesi
Name:CDKF-1
Ordered Locus Names:Os06g0334400, LOC_Os06g22820
ORF Names:OSJNBa0012F14.17
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 6

Organism-specific databases

GrameneiQ5Z754.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: EnsemblPlants/Gramene
  2. nucleus Source: EnsemblPlants/Gramene
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 479479Cyclin-dependent kinase F-1PRO_0000296105Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei291 – 2911PhosphothreonineBy similarity

Keywords - PTMi

Phosphoprotein

Expressioni

Inductioni

By auxin. Down-regulated by cytokinin.1 Publication

Gene expression databases

ExpressionAtlasiQ5Z754. baseline.

Structurei

3D structure databases

ProteinModelPortaliQ5Z754.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini24 – 419396Protein kinasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0515.
InParanoidiQ5Z754.
OMAiTEEWANF.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 2 hits.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 2 hits.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5Z754-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAIGGGGGGG SWSIHGRPDV TSRYEVLGRA GSGAYADVYR GRRRSDGAPV
60 70 80 90 100
ALKEVHDAVS ARREADALLA AAPSRHVVAL LDHFPGGDHD DDVLVLEWLP
110 120 130 140 150
LDLSAVVRAA AAARPSALPA AQRKRWMLQV LEGVAACHSA GVVHRDLKPA
160 170 180 190 200
NLLISEDGVL KVADLGQARI LQETGTYQGM HPYEQSSGVE PWVSQQRAVL
210 220 230 240 250
HGVKENHPSH DSETQTGQEP ERLTAADYLH EMDQLRAKST HGDVDKMSLQ
260 270 280 290 300
DGNASCLATC STADIDDDPF RASYSYDAEE GMLEEESGAF TSCVGTRWFR
310 320 330 340 350
APELLYGSTN YGQEVDLWSL GCILAELFNL EPIFPGTSDI DQIGRIISVL
360 370 380 390 400
GNITEETFPG CSNLPDYNKI FFNKVEKPIG LEACLPDRSA SEVSIIKRLL
410 420 430 440 450
CYDPTKRASA ADLLNDPYFA EEPLPVPIEG LQVPESKDED DDSTEEWANF
460 470
RGGDSDSDFD EFGSMDVTKT DKGFSIRFS
Length:479
Mass (Da):52,073
Last modified:November 23, 2004 - v1
Checksum:i0FA906213F770759
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti253 – 2531N → D in AK120969. (PubMed:12869764)Curated
Sequence conflicti394 – 3941S → G in AK120969. (PubMed:12869764)Curated
Sequence conflicti450 – 4501F → L in AK120969. (PubMed:12869764)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004784 Genomic DNA. Translation: BAD61885.1.
AP008212 Genomic DNA. Translation: BAF19465.1.
AK120969 mRNA. No translation available.
RefSeqiNP_001057551.1. NM_001064086.1.
UniGeneiOs.11911.

Genome annotation databases

EnsemblPlantsiOS06T0334400-01; OS06T0334400-01; OS06G0334400.
GeneIDi4340934.
KEGGiosa:4340934.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004784 Genomic DNA. Translation: BAD61885.1 .
AP008212 Genomic DNA. Translation: BAF19465.1 .
AK120969 mRNA. No translation available.
RefSeqi NP_001057551.1. NM_001064086.1.
UniGenei Os.11911.

3D structure databases

ProteinModelPortali Q5Z754.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS06T0334400-01 ; OS06T0334400-01 ; OS06G0334400 .
GeneIDi 4340934.
KEGGi osa:4340934.

Organism-specific databases

Gramenei Q5Z754.

Phylogenomic databases

eggNOGi COG0515.
InParanoidi Q5Z754.
OMAi TEEWANF.

Gene expression databases

ExpressionAtlasi Q5Z754. baseline.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 2 hits.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 2 hits.
PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  3. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.
  4. "Genome-wide identification and expression analysis of rice cell cycle genes."
    Guo J., Song J., Wang F., Zhang X.S.
    Plant Mol. Biol. 64:349-360(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION, GENE FAMILY.

Entry informationi

Entry nameiCDKF1_ORYSJ
AccessioniPrimary (citable) accession number: Q5Z754
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: November 23, 2004
Last modified: October 29, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3