Q5Z6F5 (P2C59_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable protein phosphatase 2C 59
Short name=OsPP2C59
EC=3.1.3.16

Gene names

Ordered Locus Names:	Os06g0698300, LOC_Os06g48300
ORF Names:	OsJ_021637, P0028E05.39

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	327 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 2 magnesium or manganese ions per subunit By similarity.
Sequence similarities	Belongs to the PP2C family. Contains 1 PP2C-like domain.
Sequence caution	The sequence BAF20378.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Domain	Signal
Ligand	Magnesium Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	defense response to bacterium Inferred from electronic annotation. Source: EnsemblPlants/Gramene protein dephosphorylation Inferred from electronic annotation. Source: InterPro
Cellular_component	plasma membrane Inferred from electronic annotation. Source: EnsemblPlants/Gramene
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine phosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 24	24	Potential
	Chain	25 – 327	303	Probable protein phosphatase 2C 59		PRO_0000363306
Regions
	Domain	63 – 303	241	PP2C-like
	Compositional bias	30 – 33	4	Poly-Glu
Sites
	Metal binding	100	1	Manganese 1 By similarity
	Metal binding	100	1	Manganese 2 By similarity
	Metal binding	101	1	Manganese 1; via carbonyl oxygen By similarity
	Metal binding	262	1	Manganese 2 By similarity
	Metal binding	301	1	Manganese 2 By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5Z6F5 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: 05D0F79F6826C42C	FASTA	327	34,941
	10 20 30 40 50 60 MREVLLLGSL VVLALLSLFP CCSCLSQGAE EEEDDGEVRL MGLAGEAAGS PGSGGGFSAN 70 80 90 100 110 120 GKFSYGYASS PGKRSSMEDF YDTRIDGVDG ETVGLFGVFD GHGGARAAEF VKQNLFTNLI 130 140 150 160 170 180 KHPKLFSDTK SAIAETYTST DSELLKAETS HNRDAGSTAS TAILVGDRLL VANVGDSRAV 190 200 210 220 230 240 ICRGGDAIAV SRDHKPDQSD ERQRIEDAGG FVMWAGTWRV GGVLAVSRAF GDKLLKQYVV 250 260 270 280 290 300 ADPEIKEEVV DSSLEFLILA SDGLWDVVTN EEAVAMVKPI LDSEQAAKKL LQEASQRGSA 310 320 DNITCLVVRF LEQENHLPER PTNDQAS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[3]	"The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H. PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[4]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2-327. Strain: cv. Nipponbare.
[5]	"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis." Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y. BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP005445 Genomic DNA. Translation: BAD54464.1. AP008212 Genomic DNA. Translation: BAF20378.1. Different initiation. CM000143 Genomic DNA. Translation: EAZ38154.1. AK071637 mRNA. No translation available.
RefSeq	NP_001058464.1. NM_001064999.1.
UniGene	Os.34372.
3D structure databases
HSSP	HSSP built from PDB template 1A6Q based on UniProtKB P35813.
ProteinModelPortal	Q5Z6F5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os06g48300.1; LOC_Os06g48300.1; LOC_Os06g48300.
GeneID	4341949.
KEGG	osa:4341949.
Organism-specific databases
Gramene	Q5Z6F5.
Phylogenomic databases
eggNOG	COG0631.
HOGENOM	HOG000233896.
OMA	AIAETYT.
Gene expression databases
ArrayExpress	Q5Z6F5.
Family and domain databases
Gene3D	3.60.40.10. 1 hit.
InterPro	IPR001932. PP2C-like. IPR000222. PP2C_Mn2_Asp60_BS. IPR015655. Protein_Pase_2C. [Graphical view]
PANTHER	PTHR13832. PTHR13832. 1 hit.
Pfam	PF00481. PP2C. 1 hit. [Graphical view]
SMART	SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view]
SUPFAM	SSF81606. PP2C-related. 1 hit.
PROSITE	PS01032. PP2C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P2C59_ORYSJ

Accession

Primary (citable) accession number: Q5Z6F5
Secondary accession number(s): Q0D9U5

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	November 23, 2004
Last modified:	April 3, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program