Q5Z3C0 (PATR_NOCFA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative phenylalanine aminotransferase
EC=2.6.1.-

Gene names

Name:	pat
Synonyms:	hisC2
Ordered Locus Names:	NFA_2290

Organism

Nocardia farcinica (strain IFM 10152) [Complete proteome] [HAMAP]

Taxonomic identifier

247156 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Nocardia

Protein attributes

Sequence length	358 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May catalyze the transamination reaction in phenylalanine biosynthesis By similarity. HAMAP MF_01513
Cofactor	Pyridoxal phosphate By similarity. HAMAP MF_01513
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

Ontologies

Keywords
Ligand	Pyridoxal phosphate
Molecular function	Aminotransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 358	358	Putative phenylalanine aminotransferase HAMAP MF_01513		PRO_0000153518
Amino acid modifications
	Modified residue	219	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5Z3C0 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: 03A4D02A7EB24DE5	FASTA	358	38,534
	10 20 30 40 50 60 MSARIRPDLS SIPAYTPGRS NPGAVKLASN ETTLPPLPAA AKAIAEAAEL AHRYPDNQSG 70 80 90 100 110 120 ELRAALAEFL GVRVENVAIG CGSVALCQEL VQITCSSPRD EVLFAWRSFE AYPIITQVGN 130 140 150 160 170 180 ATAVQVPLSP DYAHDLDALA AAVTEHTRLI FVCNPNNPTG TAHGRAALER FLDAVPAHVL 190 200 210 220 230 240 VVLDEAYYEY MRLTPQDRPD GVEVGRNRPN VVVLRTFSKA YGLAGLRVGY AVGDPEVITA 250 260 270 280 290 300 LMKVHIPFSV NRVAQAAAIA SLEARHELLE RTEAVIVERE RLREALLAAG YDVPPSETNF 310 320 330 340 350 VWLPLGAHSA EFGEASAAAG VLVRPYGTDG VRVTVGDPHE NEMFLRFAAD PAVVARFR

References

[1]

"The complete genomic sequence of Nocardia farcinica IFM 10152." Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K., Shiba T., Hattori M. Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004) [PubMed: 15466710] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IFM 10152.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006618 Genomic DNA. Translation: BAD55071.1.
RefSeq	YP_116435.1. NC_006361.1.
3D structure databases
ProteinModelPortal	Q5Z3C0.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3109567.
GenomeReviews	Gene locus NFA_2290 in contig AP006618_GR.
KEGG	nfa:nfa2290.
NMPDR	fig|247156.1.peg.299.
PATRIC	22729920. VBINocFar94200_0229.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG646350.
OMA	NNTKIVW.
ProtClustDB	PRK03321.
Enzyme and pathway databases
BioCyc	NFAR247156:NFA2290-MONOMER.
Family and domain databases
HAMAP	MF_01513. Phe_aminotrans_2. [Tree]
InterPro	IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR024892. AroT. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00817.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01141. HisC. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PATR_NOCFA

Accession

Primary (citable) accession number: Q5Z3C0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 10, 2006
Last sequence update:	November 23, 2004
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program