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Protein

Serine/threonine-protein kinase PknK

Gene

NFA_2870

Organism
Nocardia farcinica (strain IFM 10152)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseUniRule annotationImported, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciNFAR247156:GJ9T-297-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein kinase PknKUniRule annotation (EC:2.7.11.1UniRule annotation)
Alternative name(s):
Protein kinase KUniRule annotation
Gene namesi
Ordered Locus Names:NFA_2870Imported
OrganismiNocardia farcinica (strain IFM 10152)Imported
Taxonomic identifieri247156 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeNocardia
ProteomesiUP000006820: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi247156.nfa2870.

Structurei

3D structure databases

ProteinModelPortaliQ5Z362.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

KOiK13419.
OMAiATKFRPP.
OrthoDBiEOG69GZGV.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR016236. Ser/Thr_kinase_PknK_prd.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
PIRSFiPIRSF000574. Ser/Thr_PK_PknK_prd. 1 hit.
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5Z362-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEIGRGGFGV VYRCLQTALE RVVAVKVLPP DMDAESRERF LREEQAMGRL
60 70 80 90 100
SGHPNIVDIL QVDVTASGLP FIVMPYCTHG SLEQLIHEQG PLGWADTLRV
110 120 130 140 150
GVKLAGAIES AHRAQILHRD VKPGNVLLSS YGEPQLTDFG IARIPGGFRT
160 170 180 190 200
SSSMITGSPA FTAPEVLKGE EPTVRSDVYG LGATLFALLT GHAAFERQAG
210 220 230 240 250
EKVVAQFLRI TTQPVPDLRE QDIPAPVAEA IERAMSPDPQ QRPESAFEFG
260 270 280 290 300
EMLRAAQRAL GQLPDEMALL DTAVLLDDLG EVRATEPHPS IRTQFSTRAR
310 320 330 340 350
PSVTARRSWP LTLRPNVSQH PPGATSTTPP PTAATKFRPP TPARAPVPRP
360 370 380 390 400
RLLEVLRAGG RRRLALIHAP AGFGKSTVAA QWRAELTDQG VPVAWIGLDH
410 420 430 440 450
DDDNEVWFLA HLLQAIHRVR PAIGAGLDQA LEERPADAVA FVISTLIDEV
460 470 480 490 500
HAGGETIVVV IEDWHRITDP GAHRAMAALL DNGCHHLRFV VTSRDQSGLP
510 520 530 540 550
VNSMRVHDEL VEIGSAQLRL TRAETGQILV ERNGFELTDK QVEQIHRVTD
560 570 580 590 600
GWPAAVQLVS LALRGNPDPQ RLISALPEGG HGIREYLAEN VLDTLEPRML
610 620 630 640 650
DFLTAISVTE RVNASLAAAL SEDSEAELLL AQAEQRELFL RRIEHDPEWY
660 670 680 690 700
RMQPLFAEHL RARLERTDAA KLRALHRKAS RWYAEHQFLR KSVDHALAAT
710 720 730 740 750
DLKLALDLVE GGGMDLIDGS RLATLLGTVS KLPVQQVTSR SKLLMAVARA
760 770 780 790 800
NVNLQQSGAA RSALGKLTNM LPGGSGEDET NRQRCEAAVL AAADAVTRDQ
810 820 830 840 850
TDGVLDQVAD CLDNPDDLPA WTVSTAANVV SYVRLCTFDF DGARQIQEWA
860 870 880 890 900
QPYHEKSKDP LGTVFGLCAQ GAAAYEQLDI PGANDYFERA WEVAHSRAGP
910 920 930 940 950
RSHGVRVASA MLGELKYRAG DLATADRLLD ESHQLVTRVG TVDFLLATFV
960 970 980 990 1000
TGARVKAVRG DLATAAARLE EGERIAREYE LPRLGAHVRA ERLRLGLPVE
1010 1020 1030 1040 1050
PATESGPGPG LRRATGVAAL IAEAEETAAV RAMLAARPSH TDDAPVRRAR
1060 1070 1080 1090 1100
ALYGRTTEQG RPRAELDTAL LLAETLAASG WVGEATAMLV PAAQVCARLG
1110 1120 1130 1140
WPRPLLDAGP RVVAILRVLR GELHLSPENA DETRLPTHFL DEVLG
Length:1,145
Mass (Da):124,494
Last modified:November 23, 2004 - v1
Checksum:i39512B98DE5480C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006618 Genomic DNA. Translation: BAD55129.1.
RefSeqiWP_011206816.1. NC_006361.1.
YP_116493.1. NC_006361.1.

Genome annotation databases

EnsemblBacteriaiBAD55129; BAD55129; NFA_2870.
GeneIDi3108019.
KEGGinfa:nfa2870.
PATRICi22730044. VBINocFar94200_0289.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006618 Genomic DNA. Translation: BAD55129.1.
RefSeqiWP_011206816.1. NC_006361.1.
YP_116493.1. NC_006361.1.

3D structure databases

ProteinModelPortaliQ5Z362.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi247156.nfa2870.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD55129; BAD55129; NFA_2870.
GeneIDi3108019.
KEGGinfa:nfa2870.
PATRICi22730044. VBINocFar94200_0289.

Phylogenomic databases

KOiK13419.
OMAiATKFRPP.
OrthoDBiEOG69GZGV.

Enzyme and pathway databases

BioCyciNFAR247156:GJ9T-297-MONOMER.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR016236. Ser/Thr_kinase_PknK_prd.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
PIRSFiPIRSF000574. Ser/Thr_PK_PknK_prd. 1 hit.
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IFM 10152Imported.

Entry informationi

Entry nameiQ5Z362_NOCFA
AccessioniPrimary (citable) accession number: Q5Z362
Entry historyi
Integrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: February 4, 2015
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.