Q5Z1L0 (RS4_NOCFA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
30S ribosomal protein S4

Gene names

Name:	rpsD
Ordered Locus Names:	NFA_8360

Organism

Nocardia farcinica (strain IFM 10152) [Complete proteome] [HAMAP]

Taxonomic identifier

247156 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Nocardia › Nocardia farcinica

Protein attributes

Sequence length	201 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit By similarity. HAMAP-Rule MF_01306 With S5 and S12 plays an important role in translational accuracy By similarity. HAMAP-Rule MF_01306
Subunit structure	Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity By similarity.
Sequence similarities	Belongs to the ribosomal protein S4P family. Contains 1 S4 RNA-binding domain.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	small ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 201	201	30S ribosomal protein S4 HAMAP-Rule MF_01306		PRO_0000132427
Regions
	Domain	91 – 155	65	S4 RNA-binding

Sequences

	Sequence		Length	Mass (Da)
	Q5Z1L0 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: 98D3B1BD0D0113FC	FASTA	201	23,516
	10 20 30 40 50 60 MARYTGPITR KSRRLRVDLV GGDQAFERRP YPPGQHGRAR IKESEYLLQL QEKQKARFSY 70 80 90 100 110 120 GVMEKQFRRY YEEANRQKGK TGDNLLRLLE TRLDNVVYRA GLARTRRQAR QLVSHGHFLV 130 140 150 160 170 180 NGVKVDVPSY RVSQYDIIDV KEKSLSTLPF QVARETLGER PVPGWLQVLP GRLRILVHQE 190 200 PERAQIDVPL QEQLIVEYYS K

References

[1]

"The complete genomic sequence of Nocardia farcinica IFM 10152." Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K., Shiba T., Hattori M. Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IFM 10152.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006618 Genomic DNA. Translation: BAD55681.1.
RefSeq	YP_117045.1. NC_006361.1.
3D structure databases
ProteinModelPortal	Q5Z1L0.
SMR	Q5Z1L0. Positions 41-201.
ModBase	Search...
Protein-protein interaction databases
STRING	247156.nfa8360.
Proteomic databases
PRIDE	Q5Z1L0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAD55681; BAD55681; NFA_8360.
GeneID	3111513.
KEGG	nfa:nfa8360.
PATRIC	22731204. VBINocFar94200_0861.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0522.
KO	K02986.
OMA	THGHILV.
ProtClustDB	PRK05327.
Enzyme and pathway databases
BioCyc	NFAR247156:GJ9T-858-MONOMER.
Family and domain databases
Gene3D	1.10.1050.10. 1 hit. 3.10.290.10. 1 hit.
HAMAP	MF_01306_B. Ribosomal_S4_B.
InterPro	IPR022801. Ribosomal_S4/S9. IPR001912. Ribosomal_S4/S9_N. IPR005709. Ribosomal_S4_bac-type. IPR018079. Ribosomal_S4_CS. IPR002942. S4_RNA-bd. [Graphical view]
PANTHER	PTHR11831. PTHR11831. 1 hit.
Pfam	PF00163. Ribosomal_S4. 1 hit. PF01479. S4. 1 hit. [Graphical view]
SMART	SM00363. S4. 1 hit. [Graphical view]
TIGRFAMs	TIGR01017. rpsD_bact. 1 hit.
PROSITE	PS00632. RIBOSOMAL_S4. 1 hit. PS50889. S4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS4_NOCFA

Accession

Primary (citable) accession number: Q5Z1L0

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	November 23, 2004
Last modified:	May 1, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program