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Q5Z1H8 (GLMM_NOCFA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoglucosamine mutase
EC=5.4.2.10
Gene names
Name:glmM
Ordered Locus Names:NFA_8680
OrganismNocardia farcinica (strain IFM 10152) [Complete proteome] [HAMAP]
Taxonomic identifier247156 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Nocardia ›

Protein attributes

Sequence length458 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP-Rule MF_01554

Catalytic activity

Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP-Rule MF_01554

Cofactor

Binds 1 magnesium ion per subunit By similarity. HAMAP-Rule MF_01554

Post-translational modification

Activated by phosphorylation By similarity. HAMAP-Rule MF_01554

Sequence similarities

Belongs to the phosphohexose mutase family.

Ontologies

Keywords
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   PTMPhosphoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: HAMAP

phosphoglucosamine mutase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 458458Phosphoglucosamine mutase HAMAP-Rule MF_01554
PRO_0000147926

Sites

Active site1001Phosphoserine intermediate By similarity
Metal binding1001Magnesium; via phosphate group By similarity
Metal binding2541Magnesium By similarity
Metal binding2561Magnesium By similarity
Metal binding2581Magnesium By similarity

Amino acid modifications

Modified residue1001Phosphoserine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5Z1H8 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: FA5BE605A28ED570

FASTA45846,658
        10         20         30         40         50         60 
MGRLFGTDGV RGLANGSLSP ELALRVSGAA AQVLGRGKTR ALALVGRDPR ASGEMLEAAV 

        70         80         90        100        110        120 
TAGLTAAGVN VLSVGVLPTP AVAYLTGLYD ACLGVMISAS HNPMPDNGIK IFAAGGHKLD 

       130        140        150        160        170        180 
DAVEDRIEAL VAADDPVRPT GAGIGRVLNA SGARDHGLHI PDQYSVEGTH ERYVEHLVEA 

       190        200        210        220        230        240 
TGRDLSGLTV VVDCANGAAA EVGPAAYREA GATVIAINAE PDGLNINDGC GSTHLDQVRR 

       250        260        270        280        290        300 
AVVEHGADLG LAHDGDADRC LAVAADGSVV DGDAILAVLA IAMKESGELA QDTLVATVMS 

       310        320        330        340        350        360 
NLGLHLAMRA AGIAVRTTAV GDRYVLEELR AGGYTLGGEQ SGHVVFPKYG TTGDGVLTGL 

       370        380        390        400        410        420 
KLMARMAQTG RSLADLAGVL TTVPQVLVNV PVSDKAAVAA APDVREAVAD AERELGDSGR 

       430        440        450 
ILLRPSGTEQ LVRVMVEATD PVKAEQLAAD LAKLVASL

« Hide

References

[1]"The complete genomic sequence of Nocardia farcinica IFM 10152."
Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K., Shiba T., Hattori M.
Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IFM 10152.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006618 Genomic DNA. Translation: BAD55713.1.
RefSeqYP_117077.1. NC_006361.1.

3D structure databases

ProteinModelPortalQ5Z1H8.
ModBaseSearch...

Protein-protein interaction databases

STRING247156.nfa8680.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD55713; BAD55713; NFA_8680.
GeneID3109652.
KEGGnfa:nfa8680.
PATRIC22731270. VBINocFar94200_0894.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1109.
KOK03431.
OMATLMSNMS.

Enzyme and pathway databases

BioCycNFAR247156:GJ9T-890-MONOMER.

Family and domain databases

Gene3D3.40.120.10. 3 hits.
HAMAPMF_01554_B. GlmM_B.
InterProIPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR016066. A-D-PHexomutase_CS.
IPR005841. Alpha-D-phosphohexomutase_SF.
IPR006352. GlmM.
[Graphical view]
PfamPF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
PF00408. PGM_PMM_IV. 1 hit.
[Graphical view]
PRINTSPR00509. PGMPMM.
SUPFAMSSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMsTIGR01455. glmM. 1 hit.
PROSITEPS00710. PGM_PMM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLMM_NOCFA
AccessionPrimary (citable) accession number: Q5Z1H8
Entry history
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: November 23, 2004
Last modified: May 1, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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