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Q5Z1G7 (Q5Z1G7_NOCFA) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP MF_01201
EC=5.1.1.1 HAMAP MF_01201
Gene names
Name:alr HAMAP MF_01201 EMBL BAD55724.1
Ordered Locus Names:NFA_8790
OrganismNocardia farcinica (strain IFM 10152) [Complete proteome] [HAMAP]
Taxonomic identifier247156 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Nocardia

Protein attributes

Sequence length381 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the D-alanine required for cell wall biosynthesis By similarity. HAMAP MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP MF_01201

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site411Proton acceptor; specific for D-alanine By similarity HAMAP MF_01201
Active site2701Proton acceptor; specific for L-alanine By similarity HAMAP MF_01201

Amino acid modifications

Modified residue411N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01201

Sequences

Sequence LengthMass (Da)Tools
Q5Z1G7 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: 253A256765E85842

FASTA38139,965
        10         20         30         40         50         60 
MAGSGDVSAQ VEAVVDLDAI AHNVRVLREY AGDAAMMVVV KADGYNHGAV EVARTALAAG 

        70         80         90        100        110        120 
ARELGVTTVA EALRLREAGI TAPVLCWLNT LSADYAAAVA ADIEIGVSGT EQLRAVATAA 

       130        140        150        160        170        180 
RATGRTATVT LKVDTGLNRN GIAADELPTV LDLLGELVEE KTVRLRAMFS HLAHADEPKH 

       190        200        210        220        230        240 
PFLDEQRDRF TAAAAAATAR GLRPELLHLA NSAATVTRPD LAFDMVRPGI AVYGLSPVPE 

       250        260        270        280        290        300 
LGDFGLRPAM TFQAQVALVK RVAEGEGVSY GHQWIAPRDT TVALIPAGYA DGVFRPLSGR 

       310        320        330        340        350        360 
FDVWLGGTRR PNVGRVCMDQ FVVDLGDDAA GVAAGDTAVL FGGGPGVPGA QEWADLLGTI 

       370        380 
HYEVVCSPRG RAVRRYVGTG R

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References

[1]"The complete genomic sequence of Nocardia farcinica IFM 10152."
Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K., Shiba T., Hattori M.
Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004) [PubMed: 15466710] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IFM 10152.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006618 Genomic DNA. Translation: BAD55724.1.
RefSeqYP_117088.1. NC_006361.1.

3D structure databases

ProteinModelPortalQ5Z1G7.
SMRQ5Z1G7. Positions 12-376.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3109854.
GenomeReviewsGene locus NFA_8790 in contig AP006618_GR.
KEGGnfa:nfa8790.
NMPDRfig|247156.1.peg.923.
PATRIC22731292. VBINocFar94200_0905.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG712172.
OMAEGTPVWV.
ProtClustDBPRK00053.

Family and domain databases

HAMAPMF_01201. Ala_racemase.
[Tree]
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
[Graphical view]
Gene3DG3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit.
KOK01775.
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. Alr. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ5Z1G7_NOCFA
AccessionPrimary (citable) accession number: Q5Z1G7
Entry history
Integrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: January 25, 2012
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info