Q5Z1G2 (GCP_NOCFA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	NFA_8840

Organism

Nocardia farcinica (strain IFM 10152) [Complete proteome] [HAMAP]

Taxonomic identifier

247156 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Nocardia

Protein attributes

Sequence length	344 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 344	344	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303459

Sequences

	Sequence		Length	Mass (Da)
	Q5Z1G2 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: 7D0F82FF33C09640	FASTA	344	34,873
	10 20 30 40 50 60 MGIESSCDET GVGIVRWHPD GTCELLADEV ASSVDQHARF GGVVPEIASR AHLEAIVPAM 70 80 90 100 110 120 RRALSAAGIA KPDALAVTIG PGLAGALLVG VAAAKAYAAA WDVPFYALNH LGGHVAVDTL 130 140 150 160 170 180 EHGPMPPCVA LLVSGGHTHL LHVTDLAAPI VELGSTVDDA AGEAFDKVAR LLGLGFPGGP 190 200 210 220 230 240 ALDAAARDGD PHAIAFPRGM TGPRDPRYDF SFSGLKTAVA RHVEAAQRAG VAIADLPIPD 250 260 270 280 290 300 IAASFQEAVA DVLTMKAVRA AQDMGVDTLV LGGGATANSR IRSLAEERCA AAGLTLRVPK 310 320 330 340 PRLCTDNGVM IAALGAHVIA GGARPSPLTV ASDPGLPVSV SQIA

References

[1]

"The complete genomic sequence of Nocardia farcinica IFM 10152." Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K., Shiba T., Hattori M. Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004) [PubMed: 15466710] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IFM 10152.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006618 Genomic DNA. Translation: BAD55729.1.
RefSeq	YP_117093.1. NC_006361.1.
3D structure databases
ProteinModelPortal	Q5Z1G2.
ModBase	Search...
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3110021.
GenomeReviews	Gene locus NFA_8840 in contig AP006618_GR.
KEGG	nfa:nfa8840.
NMPDR	fig|247156.1.peg.927.
PATRIC	22731304. VBINocFar94200_0911.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304663.
OMA	PLYGVNH.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	NFAR247156:NFA8840-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_NOCFA

Accession

Primary (citable) accession number: Q5Z1G2

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	November 23, 2004
Last modified:	January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program