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Q5Z193 (Q5Z193_NOCFA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Adenosine deaminase HAMAP MF_00540
EC=3.5.4.4 HAMAP MF_00540
Alternative name(s):
Adenosine aminohydrolase HAMAP MF_00540
Gene names
Name:add HAMAP MF_00540
Ordered Locus Names:NFA_9530
OrganismNocardia farcinica (strain IFM 10152) [Complete proteome] [HAMAP]
Taxonomic identifier247156 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Nocardia

Protein attributes

Sequence length365 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Adenosine + H2O = inosine + NH3. HAMAP MF_00540

Cofactor

Binds 1 zinc ion per subunit By similarity. HAMAP MF_00540 SAAS SAAS006330

Sequence similarities

Belongs to the adenosine and AMP deaminases family. Adenosine deaminase subfamily. HAMAP MF_00540

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2131Proton donor By similarity HAMAP MF_00540
Metal binding211Zinc; catalytic By similarity HAMAP MF_00540
Metal binding231Zinc; catalytic By similarity HAMAP MF_00540
Metal binding2101Zinc; catalytic By similarity HAMAP MF_00540
Metal binding3031Zinc; catalytic By similarity HAMAP MF_00540
Binding site231Substrate By similarity HAMAP MF_00540
Binding site251Substrate By similarity HAMAP MF_00540
Binding site1831Substrate; via amide nitrogen and carbonyl oxygen By similarity HAMAP MF_00540
Site2341Important for catalytic activity By similarity HAMAP MF_00540

Sequences

Sequence LengthMass (Da)Tools
Q5Z193 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: 5EB2805C57AAF7C4

FASTA36540,072
        10         20         30         40         50         60 
MTGPTPLTLA SIRRAPKALL HDHLDGGLRP ATVLELAAEC GYDELPADTE AELAAWFREA 

        70         80         90        100        110        120 
ADSGSLERYL ETFAHTVAVM QTPEGLRRVA RECVLDLAAD GVVYAEVRYA PEQHLERGLS 

       130        140        150        160        170        180 
LDEVVEHTLA GFREGERAAA AAGQPIVVTC LLTAMRHAAR SREIAELAVR WRDRGVGGFD 

       190        200        210        220        230        240 
IAGAEAGYPP TRHLDAFEYM RANSAHFTIH AGEAFGLPSI HEALAFCGCD RLGHGVRITD 

       250        260        270        280        290        300 
DIRVGDSVAD AELGLVARYV RDKRIPLELC PSSNVQTGAV PSLDKHPFDL LARLRFRVTV 

       310        320        330        340        350        360 
NTDNRLMSDT SMSQEMHKLV QTFGYGWSDL ERFTINAMKS AFIPFPERLR IIDDIIKPGY 


AVLIG

« Hide

References

[1]"The complete genomic sequence of Nocardia farcinica IFM 10152."
Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K., Shiba T., Hattori M.
Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004) [PubMed: 15466710] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IFM 10152.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006618 Genomic DNA. Translation: BAD55798.1.
RefSeqYP_117162.1. NC_006361.1.

3D structure databases

ProteinModelPortalQ5Z193.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3109943.
GenomeReviewsGene locus NFA_9530 in contig AP006618_GR.
KEGGnfa:nfa9530.
NMPDRfig|247156.1.peg.991.
PATRIC22731446. VBINocFar94200_0982.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG630382.
OMAPYYMAMN.
ProtClustDBPRK09358.

Family and domain databases

HAMAPMF_00540. A_deaminase.
[Tree]
InterProIPR001365. A/AMP_deaminase_dom.
IPR006330. A_deaminase.
[Graphical view]
KOK01488.
PANTHERPTHR11409:SF21. PTHR11409:SF21. 1 hit.
PfamPF00962. A_deaminase. 1 hit.
[Graphical view]
TIGRFAMsTIGR01430. Aden_deam. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ5Z193_NOCFA
AccessionPrimary (citable) accession number: Q5Z193
Entry history
Integrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: December 14, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info