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Q5Z0Z9

- SYR_NOCFA

UniProt

Q5Z0Z9 - SYR_NOCFA

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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Nocardia farcinica (strain IFM 10152)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciNFAR247156:GJ9T-1072-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:NFA_10470
OrganismiNocardia farcinica (strain IFM 10152)
Taxonomic identifieri247156 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeNocardia
ProteomesiUP000006820: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 552552Arginine--tRNA ligasePRO_0000242058Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi247156.nfa10470.

Structurei

3D structure databases

ProteinModelPortaliQ5Z0Z9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi130 – 14011"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
KOiK01887.
OMAiQQEVFRS.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5Z0Z9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTPADLADLL RATAAKVLAE RGLDPAVLPD EVTVERPRNP EHGDYATNLA
60 70 80 90 100
MKVAKKAGTN PRDLAGWLAE ALGAADGITS AEVAGPGFLN IRLAAAAQGA
110 120 130 140 150
VLEQVLAAGS GYGTADTLRG TKINLEFVSA NPTGPIHLGG TRWASVGDAL
160 170 180 190 200
GRILAAQGAD VTREYYFNDH GAQIDRFANS LVAAATGQPT PDDGYAGAYI
210 220 230 240 250
GEIAEQIVAE HPEAPTLPAD QRHELFRAEG VELMFAHIKR TLHEFGTDFD
260 270 280 290 300
VYFNESTLFA SGAVEQAVET LKASGDLYEK DGAWWIASSE YGDDQDRVVI
310 320 330 340 350
KSDGNAAYIA GDIAYFQNKR SRGFDLCIYM LGADHHGYIG RLKAAAAAFG
360 370 380 390 400
DDPATVEVLI GQMVNLVRDG QAVKMSKRAG TVVTLDDLVE AIGVDAARYA
410 420 430 440 450
LVRWSVNSSV DIDLNLWTSQ KNENPVYYVQ YAHARTASIG RNAAAFDYAS
460 470 480 490 500
VTPDLSQLTA EEEGELIRTI GEYPRVVASA ASLREPHRVA RYLEELAGAY
510 520 530 540 550
HRFQTNSKLR VLPLGDDPVS PLNAARLVLV NATRQVLANG LALLGVSAPE

QM
Length:552
Mass (Da):59,065
Last modified:November 23, 2004 - v1
Checksum:iFCE2A0FCFC6A59AA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP006618 Genomic DNA. Translation: BAD55892.1.
RefSeqiYP_117256.1. NC_006361.1.

Genome annotation databases

EnsemblBacteriaiBAD55892; BAD55892; NFA_10470.
GeneIDi3109865.
KEGGinfa:nfa10470.
PATRICi22731650. VBINocFar94200_1081.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP006618 Genomic DNA. Translation: BAD55892.1 .
RefSeqi YP_117256.1. NC_006361.1.

3D structure databases

ProteinModelPortali Q5Z0Z9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 247156.nfa10470.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAD55892 ; BAD55892 ; NFA_10470 .
GeneIDi 3109865.
KEGGi nfa:nfa10470.
PATRICi 22731650. VBINocFar94200_1081.

Phylogenomic databases

eggNOGi COG0018.
KOi K01887.
OMAi QQEVFRS.
OrthoDBi EOG6JB13C.

Enzyme and pathway databases

BioCyci NFAR247156:GJ9T-1072-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IFM 10152.

Entry informationi

Entry nameiSYR_NOCFA
AccessioniPrimary (citable) accession number: Q5Z0Z9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 23, 2004
Last modified: October 29, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3