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Q5YZ36 (COX4_NOCFA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable cytochrome c oxidase polypeptide 4

EC=1.9.3.1
Alternative name(s):
Cytochrome aa3 subunit 4
Cytochrome c oxidase polypeptide IV
Gene names
Name:ctaF
Ordered Locus Names:NFA_17090
OrganismNocardia farcinica (strain IFM 10152) [Complete proteome] [HAMAP]
Taxonomic identifier247156 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeNocardia

Protein attributes

Sequence length138 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of cytochrome c oxidase, its function is unknown By similarity.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subunit structure

Associates with subunits I, II and III to form cytochrome c oxidase By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase bacterial subunit CtaF family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 138138Probable cytochrome c oxidase polypeptide 4
PRO_0000220020

Regions

Transmembrane7 – 2721Helical; Potential
Transmembrane35 – 5521Helical; Potential
Transmembrane81 – 10121Helical; Potential
Transmembrane102 – 12221Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q5YZ36 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: 3CFDDBC69437DCDB

FASTA13814,903
        10         20         30         40         50         60 
MRIEARIFEL LTVFFIIVGV VYGFFTAQSR TGVEWAGTTA IVLTAGLSLI IGTYFRFVAR 

        70         80         90        100        110        120 
RLDLRPEDYE DAEIVDGAGD LGFFSPGSFW PILLAGAGSV AALGLAFFEP WLIAVGVICV 

       130 
IAAAAGLVFE YHLGPEKH 

« Hide

References

[1]"The complete genomic sequence of Nocardia farcinica IFM 10152."
Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K., Shiba T., Hattori M.
Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IFM 10152.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP006618 Genomic DNA. Translation: BAD56555.1.
RefSeqYP_117919.1. NC_006361.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING247156.nfa17090.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD56555; BAD56555; NFA_17090.
GeneID3107213.
KEGGnfa:nfa17090.
PATRIC22733028. VBINocFar94200_1759.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGNOG07397.
OMAGTYFRFV.
OrthoDBEOG63FW2X.

Enzyme and pathway databases

BioCycNFAR247156:GJ9T-1747-MONOMER.

Family and domain databases

InterProIPR021050. Cyt_c_oxidase_su4_actinobac.
[Graphical view]
PfamPF12270. Cyt_c_ox_IV. 1 hit.
[Graphical view]
PIRSFPIRSF017385. CtaF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCOX4_NOCFA
AccessionPrimary (citable) accession number: Q5YZ36
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: November 23, 2004
Last modified: May 14, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families