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Q5YZ19 (COX3_NOCFA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable cytochrome c oxidase subunit 3
EC=1.9.3.1
Alternative name(s):
Cytochrome aa3 subunit 3
Cytochrome c oxidase polypeptide III
Gene names
Name:ctaE
Ordered Locus Names:NFA_17260
OrganismNocardia farcinica (strain IFM 10152) [Complete proteome] [HAMAP]
Taxonomic identifier247156 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Nocardia ›

Protein attributes

Sequence length203 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processaerobic electron transport chain

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 203203Probable cytochrome c oxidase subunit 3
PRO_0000183885

Regions

Transmembrane30 – 5021Helical; Potential
Transmembrane69 – 8921Helical; Potential
Transmembrane102 – 12221Helical; Potential
Transmembrane142 – 16221Helical; Potential
Transmembrane179 – 19921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q5YZ19 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: 6407DB0991065D48

FASTA20322,377
        10         20         30         40         50         60 
MTTAVGTPGS AITQRVHSLN RPNMVSVGTI IWLSSELMFF AGLFAMYFVA RAQANGNWPP 

        70         80         90        100        110        120 
EPTELNLKLA VPVTAVLVAS SFTCQMGVFA AEKGDVFGLR RWYFITLLMG AFFVAGQGYE 

       130        140        150        160        170        180 
YYHLVHEGTS ISSSAYGSVF YITTGFHGLH VIGGLIAFVF LLIRTKVSKF TPAQATAAIV 

       190        200 
VSYYWHFVDI VWIGLFATIY FVR

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References

[1]"The complete genomic sequence of Nocardia farcinica IFM 10152."
Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K., Shiba T., Hattori M.
Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IFM 10152.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006618 Genomic DNA. Translation: BAD56572.1.
RefSeqYP_117936.1. NC_006361.1.

3D structure databases

ProteinModelPortalQ5YZ19.
ModBaseSearch...

Protein-protein interaction databases

STRING247156.nfa17260.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD56572; BAD56572; NFA_17260.
GeneID3108314.
KEGGnfa:nfa17260.
PATRIC22733062. VBINocFar94200_1776.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1845.
KOK02276.
OMAGDWPPEP.
ProtClustDBCLSK2523684.

Enzyme and pathway databases

BioCycNFAR247156:GJ9T-1764-MONOMER.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. CytC_oxdse_III. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_NOCFA
AccessionPrimary (citable) accession number: Q5YZ19
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: November 23, 2004
Last modified: May 1, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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