Q5YYU5 (Q5YYU5_NOCFA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative DNA polymerase III alpha subunit EMBL BAD56646.1

Gene names

Name:	dnaE EMBL BAD56646.1
Ordered Locus Names:	NFA_18000

Organism

Nocardia farcinica (strain IFM 10152) [Complete proteome] [HAMAP]

Taxonomic identifier

247156 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Nocardia

Protein attributes

Sequence length	1196 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). SAAS SAAS004013

Ontologies

Keywords
Biological process	DNA replication SAAS SAAS004013
Cellular component	Cytoplasm SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5YYU5 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: FEED9F28061F5C92	FASTA	1,196	130,796
	10 20 30 40 50 60 MRQPPSRHLG GRTVLAASSG SFVHLHNHTE YSMLDGAAKI SPLFTEAKRL GMTAVGMTDH 70 80 90 100 110 120 GNMYGASEFY NSAKKHGLKP IIGIEAYIAP GSRFDTKRVQ WGDPGQKGDD VSGSGAYTHM 130 140 150 160 170 180 TMVAENATGL RNLFKLSSLA SIEGQLGKWA RMDAEIIAQH AEGIIATTGC PSGEVQTRLR 190 200 210 220 230 240 LGHEREALEA AAKWQEIFGP DNFFLEVMDH GLSIERRVRE GLLDIGRKLG IPPLATNDCH 250 260 270 280 290 300 YVYESDAANH EALLCVQTGK TLSDPTRFKF DGSGYYLKSG DEMRAIWDAE VPGACDNTLL 310 320 330 340 350 360 IGERVQSYDA VWEHRDRMPI FPVPEGETQA SWLHKEVMRG LERRFPNGVP EEYLRRAEYE 370 380 390 400 410 420 LDVICEMGFP AYFLVVGDLI NHAREVGIRV GPGRGSAAGS LVAYAMGITN IDPIPHGLLF 430 440 450 460 470 480 ERFLNPERVS MPDIDIDFDD RRRGEMVRYA TEKWGSDRVA QVITFGTIKT KAAIKDSARV 490 500 510 520 530 540 QFGQPGFAIA DQISKALPPP IMAKDIPLSG IMDPEHERYK EAAEVRELIA NNPDVAKIYE 550 560 570 580 590 600 TARGLEGLIR NAGVHACAVI MSSEPLMDAI PLWKRAQDGA IITGWDYPSC EAIGLLKMDF 610 620 630 640 650 660 LGLRNLTVIG DALDNIKANR GIDLDMDNLP LDDPATYELL SRGDTLGVFQ LDGSAMRDLL 670 680 690 700 710 720 RRMQPTGFED IVAVLALYRP GPMGMNAHND YADRKNGRQE VKPIHPELEE PLKDILADTY 730 740 750 760 770 780 GLIVYQEQIM QIAQKVAGYS LGRADILRRA MGKKKAEVLE AEFEGFEAGM LENGFSKPAI 790 800 810 820 830 840 KALWDTILPF AGYAFNKSHA AGYGLVSFWT AYLKANYPAE YMAGLLTSVG DDKDKAAVYL 850 860 870 880 890 900 SDCRRLGITV LPPDVNESEQ NFASVGKDIR FGLGAVRNVG ANVVASIIQA RKEKSKFTDF 910 920 930 940 950 960 SDYLNKIDAI ACTKKVTESL IKAGAFDSLG HPRKGLMLIH SDAIDAVMAT KKAEAIGQFD 970 980 990 1000 1010 1020 LFGGMDADES VTSVFNVKVP DEEWETKHKL ALEREMLGLY VSGHPLNGVE HVLAAQADTQ 1030 1040 1050 1060 1070 1080 IPAILEGDVK DGAQVTIGGI LASVNRRINK NGLAWASAQL EDLTGGIEVL FFPQAYSVYG 1090 1100 1110 1120 1130 1140 ADVVEDAVVL VKARVSVRDD RISLIANDLA VPDLSAIGVA KPLAVTITSR MCTPDKIGEL 1150 1160 1170 1180 1190 KRVLTRHPGT SDVHVRYVGA RDKTTMLKLS DSLRVSPSSA LFGDLKALLG PSCLTS

References

[1]

"The complete genomic sequence of Nocardia farcinica IFM 10152." Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K., Shiba T., Hattori M. Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004) [PubMed: 15466710] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IFM 10152.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006618 Genomic DNA. Translation: BAD56646.1.
RefSeq	YP_118010.1. NC_006361.1.
3D structure databases
ProteinModelPortal	Q5YYU5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3109822.
GenomeReviews	Gene locus NFA_18000 in contig AP006618_GR.
KEGG	nfa:nfa18000.
NMPDR	fig|247156.1.peg.1812.
PATRIC	22733210. VBINocFar94200_1850.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734490.
OMA	RVLQMPY.
ProtClustDB	PRK05673.
Family and domain databases
InterPro	IPR011708. DNA_pol3_alpha. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K02337.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q5YYU5_NOCFA

Accession

Primary (citable) accession number: Q5YYU5

Entry history

Integrated into UniProtKB/TrEMBL:	November 23, 2004
Last sequence update:	November 23, 2004
Last modified:	December 14, 2011
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)