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Q5YYG7 (CAPP_NOCFA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppc
Ordered Locus Names:NFA_19280
OrganismNocardia farcinica (strain IFM 10152) [Complete proteome] [HAMAP]
Taxonomic identifier247156 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeNocardia

Protein attributes

Sequence length923 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 923923Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
PRO_0000166606

Sites

Active site1491 By similarity
Active site5851 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5YYG7 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: FE19067A3E1A9B9B

FASTA923100,839
        10         20         30         40         50         60 
MTEPRIETEQ DATRPLRDDI RFLGGVLGDT IRDHEGPEVF DLIERVRIEA FRVRREEVGR 

        70         80         90        100        110        120 
SAVAEMLRGV DIAVALPLIR AFSYFVLLAN LAEDIQRDRR RAVHVAAGEP PQDSSLAATY 

       130        140        150        160        170        180 
RKLDAAALDA AAVADLLSDA LVSPVITAHP TETRRRTVFD AQTRITELMR ARQRATDPAE 

       190        200        210        220        230        240 
RAALESRIRR QVLSLWRTAL IRLARLRIQD EIAVGLRYYE LTLFDVIPAI NAEVRAALRA 

       250        260        270        280        290        300 
RWPGADLLAR PILRPGSWIG GDRDGNPYVT AEVVRHAATQ AAGVALRRYL AELVELAKTL 

       310        320        330        340        350        360 
SLSARLVPVT PRVAELAAAG YPDPATHGDE PYRRALHHIR VRLSATADRV LDAPVPEAVA 

       370        380        390        400        410        420 
EPDAQPYAGP REFLDDLDAI DASLRASGDG LLADDRLAAL RHAVETFGFH LQGLDMRQNS 

       430        440        450        460        470        480 
EVHEQVVAEL LAWAGVHPAY GDLPEDARVE LLAAELRTRR PLLGPHARLS EQAAKEVGIV 

       490        500        510        520        530        540 
RAAKQVVDTF GPEAVPNYII SMCTSVSDML EAALLLKEGG LLDPGAPEGS PSCTVNIVPL 

       550        560        570        580        590        600 
FETIEDLGAG AATLAAALEV PVYRELVAAA GMRQEVMLGY SDSNKDGGYL AANWALYRAE 

       610        620        630        640        650        660 
LDLVEVARKT GIRLRLFHGR GGTVGRGGGR SYDAILAQPA GAVRGALRLT EQGEVIAAKY 

       670        680        690        700        710        720 
AEPGAAHRNL ESLIAGTLES TLLDVEGLGA DAEPAYELMD ELAALARAAY ARLVHETPGF 

       730        740        750        760        770        780 
VEYFRQSTPV AEVGDLNIGS RPASRKPTNS VSDLRAIPWV MAWSQARVML PGWYGTGAAL 

       790        800        810        820        830        840 
EEWVGGDPGR LARLTDLYRR WPFFRTVLSN LAQVMAKSDL DIAARYAELV DDAALRDQIF 

       850        860        870        880        890        900 
GMIREEHART LRMHAAITGH DQLLADNRSL AESIHNRFPY LEPLNQMQVE LLRRLRSGDD 

       910        920 
SELVKRGILL TMNGLATALR NSG 

« Hide

References

[1]"The complete genomic sequence of Nocardia farcinica IFM 10152."
Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K., Shiba T., Hattori M.
Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IFM 10152.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP006618 Genomic DNA. Translation: BAD56774.1.
RefSeqYP_118138.1. NC_006361.1.

3D structure databases

ProteinModelPortalQ5YYG7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING247156.nfa19280.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD56774; BAD56774; NFA_19280.
GeneID3111383.
KEGGnfa:nfa19280.
PATRIC22733482. VBINocFar94200_1982.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2352.
KOK01595.
OMAWYGAGSA.
OrthoDBEOG6TJ7T8.

Enzyme and pathway databases

BioCycNFAR247156:GJ9T-1970-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPP_NOCFA
AccessionPrimary (citable) accession number: Q5YYG7
Entry history
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: November 23, 2004
Last modified: May 14, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families