Q5YY83 (KCY_NOCFA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase
Short name=CK
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	NFA_20120

Organism

Nocardia farcinica (strain IFM 10152) [Complete proteome] [HAMAP]

Taxonomic identifier

247156 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Nocardia

Protein attributes

Sequence length	232 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity HAMAP MF_00238.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.
Sequence caution	The sequence BAD56858.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 232	232	Cytidylate kinase HAMAP MF_00238		PRO_0000131947
Regions
	Nucleotide binding	13 – 21	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5YY83 [UniParc]. Last modified February 15, 2005. Version 2. Checksum: 928F4BA45A599611	FASTA	232	24,549
	10 20 30 40 50 60 MSEDTPLVVA MDGPSGTGKS SVSRRLATRL GARYLDTGAM YRVATLRVLR AGVELTDPAA 70 80 90 100 110 120 IAAAVKELPL TIGTDPSREV IELDGEDVSA EIRGDAVTKA VSAVSAVPEV RDLLVAAQRD 130 140 150 160 170 180 IAADARRIVV EGRDIGTVVL PAADAKIYLT ASAEARAERR NQQNIREGRG DDYAAVLADV 190 200 210 220 230 QRRDTLDSTR AVSPLRPAAD AVLVDTSELT MDEVIDELSR VVAQQISTGS AQ

References

[1]

"The complete genomic sequence of Nocardia farcinica IFM 10152." Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K., Shiba T., Hattori M. Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004) [PubMed: 15466710] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IFM 10152.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006618 Genomic DNA. Translation: BAD56858.1. Different initiation.
RefSeq	YP_118222.1. NC_006361.1.
3D structure databases
ProteinModelPortal	Q5YY83.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3109845.
GenomeReviews	Gene locus NFA_20120 in contig AP006618_GR.
KEGG	nfa:nfa20120.
NMPDR	fig|247156.1.peg.2015.
PATRIC	22733648. VBINocFar94200_2062.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG354377.
OMA	DIGTVIC.
ProtClustDB	PRK00023.
Enzyme and pathway databases
BioCyc	NFAR247156:NFA20120-MONOMER.
Family and domain databases
HAMAP	MF_00238. Cytidyl_kinase_type1. [Tree]
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kinase_dom. [Graphical view]
KO	K00945.
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00017. Cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_NOCFA

Accession

Primary (citable) accession number: Q5YY83

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 15, 2005
Last sequence update:	February 15, 2005
Last modified:	January 25, 2012
This is version 46 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program