ID   Q5YUS9_NOCFA            Unreviewed;       753 AA.
AC   Q5YUS9;
DT   23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT   23-NOV-2004, sequence version 1.
DT   27-MAR-2024, entry version 114.
DE   SubName: Full=Putative histidine kinase {ECO:0000313|EMBL:BAD58062.1};
GN   OrderedLocusNames=NFA_32150 {ECO:0000313|EMBL:BAD58062.1};
OS   Nocardia farcinica (strain IFM 10152).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Nocardia.
OX   NCBI_TaxID=247156 {ECO:0000313|EMBL:BAD58062.1, ECO:0000313|Proteomes:UP000006820};
RN   [1] {ECO:0000313|EMBL:BAD58062.1, ECO:0000313|Proteomes:UP000006820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IFM 10152 {ECO:0000313|EMBL:BAD58062.1,
RC   ECO:0000313|Proteomes:UP000006820};
RX   PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA   Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA   Shiba T., Hattori M.;
RT   "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
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DR   EMBL; AP006618; BAD58062.1; -; Genomic_DNA.
DR   RefSeq; WP_011209747.1; NC_006361.1.
DR   AlphaFoldDB; Q5YUS9; -.
DR   STRING; 247156.NFA_32150; -.
DR   GeneID; 61133931; -.
DR   KEGG; nfa:NFA_32150; -.
DR   eggNOG; COG2172; Bacteria.
DR   eggNOG; COG2202; Bacteria.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_000445_43_2_11; -.
DR   OrthoDB; 163538at2; -.
DR   Proteomes; UP000006820; Chromosome.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd16936; HATPase_RsbW-like; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 1.10.1240.30; KaiA/RbsU domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR017944; KaiA/RbsU_helical_domain_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR014787; PSer_Pase_RsbU_N.
DR   NCBIfam; TIGR00229; sensory_box; 2.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF13581; HATPase_c_2; 1.
DR   Pfam; PF13188; PAS_8; 1.
DR   Pfam; PF08673; RsbU_N; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:BAD58062.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006820};
KW   Transferase {ECO:0000313|EMBL:BAD58062.1}.
FT   DOMAIN          110..147
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          176..228
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
SQ   SEQUENCE   753 AA;  80407 MW;  0398AA6B1535043D CRC64;
     MSEALPGFLD DYTEALRRHL DSPTHDTLTE GYDLGRRALV EGISLLDLTE HHFRLAAEAE
     RAAADPRVAE TALEFLLQTL AALDIATRGY LDGTRRYEQQ RSRADDLAGR DAFRTALVES
     LQDGFFVADA TGAIIEVNSA FGALTGYGAA GLPYPLPHPW SLPDGPRYPD LGTEASRFVL
     PIRHRDGRRL WLAVSTSALV KPENNELVYV GTIRDVTAEH DAQARDQAAS RLATAVGAAT
     TVVEVLSVGL DELRGTVGAE AAVVMVWPTR NGAPEVYVSG EAGADAADDT TRRLLDRARR
     RPPRSLSAIP EQADSSEGIV APLGETGDAA LWLRFAAPRA ISSADWTLFS LLIGHLSVAV
     QRARNFDQAR ATSLTLQRAM LGPIELPPRF SVHYEPALPP LEIGGDWYDV VPLRDGTIGV
     VVGDCVGRGL SAAVVMGQLR TAGRALLLRG AGPAQLLAEL DTVAARIPGA MCTTACVAVL
     DPVRGIVRYS SAGHMPPILA EVGKPGRLLE GGRSVPLATF EMPRRPEATT ALAPGSTLVL
     FTDGLVEQRG VDIDEGFAKI CAVLADTGGR LPREVADAVL RELSPAAGYD DDVAMVVYRQ
     PPAPLHLRVP AEATRLSALR RTLQAWFSAA AVPHDLAADL VAAANEACSN SIEHAYRAAA
     DSGEVVDLAA RIELDPDGDT ERLVIEVVDT GTWQPRSPDP GYRGRGLDMM RALTEELDID
     HSGPGTRVRM SVTLPAIKSP VANPLRGTQR RSG
//