Q5YUA1 (CYSD_NOCFA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sulfate adenylyltransferase subunit 2
EC=2.7.7.4

Alternative name(s):
ATP-sulfurylase small subunit
Sulfate adenylate transferase
Short name=SAT

Gene names

Name:	cysD
Ordered Locus Names:	NFA_33930

Organism

Nocardia farcinica (strain IFM 10152) [Complete proteome] [HAMAP]

Taxonomic identifier

247156 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Nocardia

Protein attributes

Sequence length	308 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of CysD, the smaller subunit, and CysN By similarity.
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 308	308	Sulfate adenylyltransferase subunit 2 HAMAP MF_00064		PRO_0000340209

Sequences

	Sequence		Length	Mass (Da)
	Q5YUA1 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: 87559F85D0F81695	FASTA	308	35,373
	10 20 30 40 50 60 MTTLVHDEHP GLTHLQRLEA DSIQIIREAV AESERPVMLY SIGKDSSVLL HLARKAFRPS 70 80 90 100 110 120 RLPFPLLHVD TTWKFRAMYA FRDAVAAEPD LDLIVHRNPD CVAQGINPFD HGSALHTQMW 130 140 150 160 170 180 KTEGLKQALD QHGFDLAFGG ARRDEEKSRA KERVFSIRSA QHRWDPKRQR PELWRLYNAS 190 200 210 220 230 240 KRPGESVRVF PLSNWTELDI WQYIHREAIP LVPLYFAALR PVVERDGTLI MVDDDRMRLD 250 260 270 280 290 300 PGEVPQERMV RFRTLGCYPL SGAIPSTATT VPEVVQEMLL TTSSERQGRI IDHDGSASME KKKQEGYF

References

[1]

"The complete genomic sequence of Nocardia farcinica IFM 10152." Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K., Shiba T., Hattori M. Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004) [PubMed: 15466710] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IFM 10152.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006618 Genomic DNA. Translation: BAD58240.1.
RefSeq	YP_119604.1. NC_006361.1.
3D structure databases
HSSP	HSSP built from PDB template 1ZUN based on UniProtKB Q87WW0.
ProteinModelPortal	Q5YUA1.
SMR	Q5YUA1. Positions 12-218.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3109472.
GenomeReviews	Gene locus NFA_33930 in contig AP006618_GR.
KEGG	nfa:nfa33930.
NMPDR	fig|247156.1.peg.3316.
PATRIC	22736416. VBINocFar94200_3444.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG758022.
OMA	NARIHPG.
ProtClustDB	PRK12563.
Enzyme and pathway databases
BioCyc	NFAR247156:NFA33930-MONOMER.
Family and domain databases
HAMAP	MF_00064. Sulf_adenylyltr_sub2. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K00957.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSD_NOCFA

Accession

Primary (citable) accession number: Q5YUA1

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	November 23, 2004
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program