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Protein

Glutamate decarboxylase

Gene

NFA_35400

Organism
Nocardia farcinica (strain IFM 10152)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciNFAR247156:GJ9T-3590-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:NFA_35400Imported
OrganismiNocardia farcinica (strain IFM 10152)Imported
Taxonomic identifieri247156 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeNocardia
ProteomesiUP000006820 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi247156.nfa35400.

Structurei

3D structure databases

ProteinModelPortaliQ5YTV3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

KOiK01580.
OMAiDPDLVWD.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5YTV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLSHPSFPQ DPGPSEVAVN PVFTREPVSV PRDRLPAGEL DADIAYQVVH
60 70 80 90 100
DELMLDGNAR LNLATFVTTW MEPSARVLMA ECFDKNMIDK DEYPRTADLE
110 120 130 140 150
QRCVRMLADL WHAADPAHAT GCSTTGSSEA CMLAGLALKR RWQHRRRAAG
160 170 180 190 200
LSTERPNLVM GANVQVCWEK FADYWDVEAR LVPMAGDRFH LTAEAALPHC
210 220 230 240 250
DENTIGVVAV LGSTFDGSYE PVAEICAALD ELERQRGWDI PVHVDGASGA
260 270 280 290 300
MVAPFCDPDL VWDFRLPRVA SVNTSGHKYG LVYPGVGWVV WRDAAALPED
310 320 330 340 350
LIFRVNYLGG QMPTFALNFS RPGAQVVAQY YTFLRLGRSG YTRVQQYCRD
360 370 380 390 400
VATRLADRIA ALGAFRLLTD GRQLPVFAFT LAEGETGYSV FDVSAALREQ
410 420 430 440 450
GWLVPAYTFP ADREDLAVLR IVVRNGFSHD LADMLLDALA AVLPRLRAQD
460 470
RPQHGPDTAT FAHGAQAPSG H
Length:471
Mass (Da):51,908
Last modified:November 22, 2004 - v1
Checksum:i930575B0765E6AB4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006618 Genomic DNA. Translation: BAD58388.1.
RefSeqiYP_119752.1. NC_006361.1.

Genome annotation databases

EnsemblBacteriaiBAD58388; BAD58388; NFA_35400.
KEGGinfa:nfa35400.
PATRICi22736696. VBINocFar94200_3584.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006618 Genomic DNA. Translation: BAD58388.1.
RefSeqiYP_119752.1. NC_006361.1.

3D structure databases

ProteinModelPortaliQ5YTV3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi247156.nfa35400.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD58388; BAD58388; NFA_35400.
KEGGinfa:nfa35400.
PATRICi22736696. VBINocFar94200_3584.

Phylogenomic databases

KOiK01580.
OMAiDPDLVWD.
OrthoDBiEOG6TFCPW.

Enzyme and pathway databases

BioCyciNFAR247156:GJ9T-3590-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IFM 10152Imported.

Entry informationi

Entry nameiQ5YTV3_NOCFA
AccessioniPrimary (citable) accession number: Q5YTV3
Entry historyi
Integrated into UniProtKB/TrEMBL: November 22, 2004
Last sequence update: November 22, 2004
Last modified: March 31, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.