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Q5YTQ5

- PGK_NOCFA

UniProt

Q5YTQ5 - PGK_NOCFA

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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Nocardia farcinica (strain IFM 10152)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei40 – 401SubstrateUniRule annotation
Binding sitei122 – 1221SubstrateUniRule annotation
Binding sitei162 – 1621SubstrateUniRule annotation
Binding sitei212 – 2121ATPUniRule annotation
Binding sitei300 – 3001ATP; via carbonyl oxygenUniRule annotation
Binding sitei331 – 3311ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi360 – 3634ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciNFAR247156:GJ9T-3638-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:NFA_35880
OrganismiNocardia farcinica (strain IFM 10152)
Taxonomic identifieri247156 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeNocardia
ProteomesiUP000006820: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 410410Phosphoglycerate kinasePRO_1000009639Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi247156.nfa35880.

Structurei

3D structure databases

ProteinModelPortaliQ5YTQ5.
SMRiQ5YTQ5. Positions 3-406.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni24 – 263Substrate bindingUniRule annotation
Regioni63 – 664Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0126.
KOiK00927.
OMAiHASVYDI.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5YTQ5 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAVKTLQDLL NEGVEGRGVL VRSDLNVPLD DNGQITDPGR IIASIPTLKA
60 70 80 90 100
LVEAGAKVVV TAHLGRPKGE PDPKFSLAPV AAKLAELLGR NVQLAGDVVG
110 120 130 140 150
YDALSRSEGL TDGDVLLLEN VRFDPRETSK DEAERGKLAA ALVELVGEDG
160 170 180 190 200
AFVSDGFGVV HRKQASVYDV AKLLPHYAGT LVAAEVDVLA KLTDNTERPY
210 220 230 240 250
AVVLGGSKVS DKLAVIEALA PKVDTLVIGG GMCFTFLAAQ GLSVGSSLLQ
260 270 280 290 300
EEMIDTCKGL LERYADVIHL PRDVVVADSF SADAESKCVP ANEIPDGWMG
310 320 330 340 350
LDIGAESVDR FAALLTEAKT VFWNGPMGVF EFEKFAAGTR GVAEAIVAAT
360 370 380 390 400
GKGAFTVVGG GDSAAAVRAL GLPEDGFSHI STGGGASLEY LEGKELPGIS
410
VLEDTAPEGS
Length:410
Mass (Da):42,608
Last modified:November 23, 2004 - v1
Checksum:i37A5875F2363D7E5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP006618 Genomic DNA. Translation: BAD58436.1.
RefSeqiWP_011210121.1. NC_006361.1.
YP_119800.1. NC_006361.1.

Genome annotation databases

EnsemblBacteriaiBAD58436; BAD58436; NFA_35880.
GeneIDi3111366.
KEGGinfa:nfa35880.
PATRICi22736792. VBINocFar94200_3632.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP006618 Genomic DNA. Translation: BAD58436.1 .
RefSeqi WP_011210121.1. NC_006361.1.
YP_119800.1. NC_006361.1.

3D structure databases

ProteinModelPortali Q5YTQ5.
SMRi Q5YTQ5. Positions 3-406.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 247156.nfa35880.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAD58436 ; BAD58436 ; NFA_35880 .
GeneIDi 3111366.
KEGGi nfa:nfa35880.
PATRICi 22736792. VBINocFar94200_3632.

Phylogenomic databases

eggNOGi COG0126.
KOi K00927.
OMAi HASVYDI.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci NFAR247156:GJ9T-3638-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IFM 10152.

Entry informationi

Entry nameiPGK_NOCFA
AccessioniPrimary (citable) accession number: Q5YTQ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 23, 2004
Last modified: October 29, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3