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Q5YTQ5

- PGK_NOCFA

UniProt

Q5YTQ5 - PGK_NOCFA

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Nocardia farcinica (strain IFM 10152)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (23 Nov 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei40 – 401SubstrateUniRule annotation
    Binding sitei122 – 1221SubstrateUniRule annotation
    Binding sitei162 – 1621SubstrateUniRule annotation
    Binding sitei212 – 2121ATPUniRule annotation
    Binding sitei300 – 3001ATP; via carbonyl oxygenUniRule annotation
    Binding sitei331 – 3311ATPUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi360 – 3634ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciNFAR247156:GJ9T-3638-MONOMER.
    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
    Gene namesi
    Name:pgkUniRule annotation
    Ordered Locus Names:NFA_35880
    OrganismiNocardia farcinica (strain IFM 10152)
    Taxonomic identifieri247156 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeNocardia
    ProteomesiUP000006820: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 410410Phosphoglycerate kinasePRO_1000009639Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi247156.nfa35880.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5YTQ5.
    SMRiQ5YTQ5. Positions 3-406.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni24 – 263Substrate bindingUniRule annotation
    Regioni63 – 664Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0126.
    KOiK00927.
    OMAiHASVYDI.
    OrthoDBiEOG64N9Z0.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5YTQ5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAVKTLQDLL NEGVEGRGVL VRSDLNVPLD DNGQITDPGR IIASIPTLKA    50
    LVEAGAKVVV TAHLGRPKGE PDPKFSLAPV AAKLAELLGR NVQLAGDVVG 100
    YDALSRSEGL TDGDVLLLEN VRFDPRETSK DEAERGKLAA ALVELVGEDG 150
    AFVSDGFGVV HRKQASVYDV AKLLPHYAGT LVAAEVDVLA KLTDNTERPY 200
    AVVLGGSKVS DKLAVIEALA PKVDTLVIGG GMCFTFLAAQ GLSVGSSLLQ 250
    EEMIDTCKGL LERYADVIHL PRDVVVADSF SADAESKCVP ANEIPDGWMG 300
    LDIGAESVDR FAALLTEAKT VFWNGPMGVF EFEKFAAGTR GVAEAIVAAT 350
    GKGAFTVVGG GDSAAAVRAL GLPEDGFSHI STGGGASLEY LEGKELPGIS 400
    VLEDTAPEGS 410
    Length:410
    Mass (Da):42,608
    Last modified:November 23, 2004 - v1
    Checksum:i37A5875F2363D7E5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP006618 Genomic DNA. Translation: BAD58436.1.
    RefSeqiWP_011210121.1. NC_006361.1.
    YP_119800.1. NC_006361.1.

    Genome annotation databases

    EnsemblBacteriaiBAD58436; BAD58436; NFA_35880.
    GeneIDi3111366.
    KEGGinfa:nfa35880.
    PATRICi22736792. VBINocFar94200_3632.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP006618 Genomic DNA. Translation: BAD58436.1 .
    RefSeqi WP_011210121.1. NC_006361.1.
    YP_119800.1. NC_006361.1.

    3D structure databases

    ProteinModelPortali Q5YTQ5.
    SMRi Q5YTQ5. Positions 3-406.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 247156.nfa35880.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAD58436 ; BAD58436 ; NFA_35880 .
    GeneIDi 3111366.
    KEGGi nfa:nfa35880.
    PATRICi 22736792. VBINocFar94200_3632.

    Phylogenomic databases

    eggNOGi COG0126.
    KOi K00927.
    OMAi HASVYDI.
    OrthoDBi EOG64N9Z0.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .
    BioCyci NFAR247156:GJ9T-3638-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: IFM 10152.

    Entry informationi

    Entry nameiPGK_NOCFA
    AccessioniPrimary (citable) accession number: Q5YTQ5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: November 23, 2004
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3