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Reviewed, UniProtKB/Swiss-Prot Q5YT53 (AHPD_NOCFA)

Last modified November 3, 2009. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Alkyl hydroperoxide reductase ahpD
    EC=1.11.1.15
Alternative name(s):
    Alkylhydroperoxidase ahpD
Gene names
Name: ahpD
Ordered Locus Names: NFA_37900
OrganismNocardia farcinica [Complete proteome] [HAMAP]
Taxonomic identifier37329 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeNocardia

Protein attributes

Sequence length179 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the ahpC active site cysteine residues and for the regeneration of the ahpC enzyme activity By similarity.

Catalytic activity

2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. HAMAP MF_01676

Subunit structure

Homotrimer By similarity.

Sequence similarities

Belongs to the ahpD family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 179179Alkyl hydroperoxide reductase ahpD HAMAP MF_01676
PRO_0000359502

Sites

Active site1301Proton donor By similarity
Active site1331Cysteine sulfenic acid (-SOH) intermediate By similarity

Amino acid modifications

Disulfide bond130 ↔ 133Alternate By similarity
Disulfide bond133Interchain (with ahpC); in linked form By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5YT53-1 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: 78EF0FFEA2929936

FASTA17918,986
        10         20         30         40         50         60 
MSIENLKNSL PEYAKDLKLN LSSIARSTVL NEQQLWGTLL ASAAATRSAT TLREIAEEAA 

        70         80         90        100        110        120 
DVLSAEAYNA ALGAASIMGM NNVFYRGKAF LGGRYDDLRA GLRMQIIGNP GVDKADFELW 

       130        140        150        160        170 
SFAVSSINGC AHCLEAHEHT LREAGVSREV IFESLRVAAI VAGVGQAVQS TEALAAAAV 

« Hide

References

[1]"The complete genomic sequence of Nocardia farcinica IFM 10152."
Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K., Shiba T., Hattori M.
Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004) [PubMed: 15466710] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IFM 10152.

Cross-references

Sequence databases

AP006618 Genomic DNA. Translation: BAD58638.1.
RefSeqYP_120002.1.

3D structure databases

SMRQ5YT53. Positions 2-175.
ModBaseSearch...

Protein family/group databases

PeroxiBase4583. NfaAhpD.

Genome annotation databases

GeneID3109919.
GenomeReviewsGene locus NFA_37900 in contig AP006618_GR.
KEGGnfa:nfa37900.
NMPDRfig|247156.1.peg.3691.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ5YT53.
OMAMAMNNVY.

Enzyme and pathway databases

BioCycNFAR247156:NFA37900-MON.

Family and domain databases

HAMAPMF_01676.
[Tree]
InterProIPR004674. AhpD.
IPR004675. AhpD_core.
IPR003779. CMD.
[Graphical view]
PfamPF02627. CMD. 1 hit.
[Graphical view]
TIGRFAMsTIGR00777. ahpD. 1 hit.
TIGR00778. ahpD_dom. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAHPD_NOCFA
AccessionPrimary (citable) accession number: Q5YT53
Entry history
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: November 23, 2004
Last modified: November 3, 2009
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents