Q5YSX4 (Q5YSX4_NOCFA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative dihydrodipicolinate synthase EMBL BAD58717.1

Gene names

Name:	dapA EMBL BAD58717.1
Ordered Locus Names:	NFA_38690

Organism

Nocardia farcinica (strain IFM 10152) [Complete proteome] [HAMAP]

Taxonomic identifier

247156 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Nocardia

Protein attributes

Sequence length	302 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H2O. SAAS SAAS005263
Pathway	Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4. SAAS SAAS005263
Subunit structure	Homotetramer By similarity. SAAS SAAS005263
Subcellular location	Cytoplasm By similarity SAAS SAAS005263.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Diaminopimelate biosynthesis SAAS SAAS005263 Lysine biosynthesis SAAS SAAS005263
Cellular component	Cytoplasm SAAS SAAS005263
Ligand	Schiff base SAAS SAAS005263
Molecular function	Lyase SAAS SAAS005263
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	diaminopimelate biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	dihydrodipicolinate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5YSX4 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: E73DCAB6D1405FE5	FASTA	302	31,685
	10 20 30 40 50 60 MTNGESTPTE LRASGTVGVA MVTPFSADGK LDVDAGVSLA AHLVDRGVDL LAISGTTGES 70 80 90 100 110 120 PTTTESEKFD LLHAVVDAVG DRATVIAGAG TYDTAHSIEL ARNAERAGAH GLLVVTPYYS 130 140 150 160 170 180 RPSQDGLYAH FTAVADATDL PVTLYDIPPR SIIPIGPETL RRLADHPRIV AVKDAKGDLN 190 200 210 220 230 240 SGADIIAHTS LDYYSGDDCL NLPWLSIGAV GFISVIGHLV PERLREMYDA FVAGDVVRAR 250 260 270 280 290 300 EINASLVPLN AAMARLGGVS MTKAGLRLLG IDVGEPRLPQ LMPNTAQLDQ LSADLRTAGV LV

References

[1]

"The complete genomic sequence of Nocardia farcinica IFM 10152." Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K., Shiba T., Hattori M. Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004) [PubMed: 15466710] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IFM 10152.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006618 Genomic DNA. Translation: BAD58717.1.
RefSeq	YP_120081.1. NC_006361.1.
3D structure databases
ProteinModelPortal	Q5YSX4.
SMR	Q5YSX4. Positions 15-301.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3109805.
GenomeReviews	Gene locus NFA_38690 in contig AP006618_GR.
KEGG	nfa:nfa38690.
NMPDR	fig|247156.1.peg.3765.
PATRIC	22737364. VBINocFar94200_3914.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG358848.
OMA	YSRPTQA.
ProtClustDB	PRK03170.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR002220. Dihydrodipicolinate_synth-like. IPR020625. Dihydrodipicolinate_synth_AS. IPR005263. Dihydrodipicolinate_synth_DapA. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01714.
PANTHER	PTHR12128. DHDPS. 1 hit.
Pfam	PF00701. DHDPS. 1 hit. [Graphical view]
PIRSF	PIRSF001365. DHDPS. 1 hit.
PRINTS	PR00146. DHPICSNTHASE.
TIGRFAMs	TIGR00674. DapA. 1 hit.
PROSITE	PS00666. DHDPS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5YSX4_NOCFA

Accession

Primary (citable) accession number: Q5YSX4

Entry history

Integrated into UniProtKB/TrEMBL:	November 23, 2004
Last sequence update:	November 23, 2004
Last modified:	December 14, 2011
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)