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Q5YPP1

- G6PI_NOCFA

UniProt

Q5YPP1 - G6PI_NOCFA

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Nocardia farcinica (strain IFM 10152)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei359 – 3591Proton donorUniRule annotation
Active sitei390 – 3901UniRule annotation
Active sitei516 – 5161UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciNFAR247156:GJ9T-5066-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:NFA_49980
OrganismiNocardia farcinica (strain IFM 10152)
Taxonomic identifieri247156 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeNocardia
ProteomesiUP000006820: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 551551Glucose-6-phosphate isomerasePRO_0000180696Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi247156.nfa49980.

Structurei

3D structure databases

ProteinModelPortaliQ5YPP1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
KOiK01810.
OMAiHKILAAN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5YPP1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSTLADVSSD ITASAAWRKL HDHHGALAQR HLREIFAEDP ERGRELTLQV
60 70 80 90 100
ADLHIDYSKH RATRETLQLL VELAREAGVE AHRDAMFAGE HINTSEDRAV
110 120 130 140 150
GHVALRLPAG RTMTIDGADA GAQVHEVLRR MGEFTDALRS GQWRGATGER
160 170 180 190 200
IETVVNIGIG GSDLGPVMVH QALRHYADAG ITARFVSNVD PADLVAELTG
210 220 230 240 250
LNPATTLFIV ASKTFSTLET LTNATAARRW LVAALGEDAV AKHFVAVSTN
260 270 280 290 300
AERVSAFGID TANMFGFWDW VGGRYSVDSA IGLSVMATIG KERFAEFLAG
310 320 330 340 350
MHAVDTHFAT APLEANAPVL LGLLGIWYAN FFGAESRAVL PYSNDLARFP
360 370 380 390 400
AYLQQLTMES NGKSVRADGT PVTTATGEIF WGEPGTNGQH AFYQLLHQGT
410 420 430 440 450
RLIPADFIGF ARPTDDLPTA DGTGSMHDVL MSNLFAQTKV LAFGKTAEEI
460 470 480 490 500
AAEGTAPNLV PHKVMPGNRP STTILAPQLT PAVVGQLIAL YEHQVFVEGV
510 520 530 540 550
IWGIDSFDQW GVELGKQQAL ALAALLTAAE DPAPQDDSST DALIRWYRAH

R
Length:551
Mass (Da):59,471
Last modified:November 23, 2004 - v1
Checksum:iF22568B0F195B6EF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP006618 Genomic DNA. Translation: BAD59850.1.
RefSeqiYP_121214.1. NC_006361.1.

Genome annotation databases

EnsemblBacteriaiBAD59850; BAD59850; NFA_49980.
GeneIDi3111365.
KEGGinfa:nfa49980.
PATRICi22739577. VBINocFar94200_5011.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP006618 Genomic DNA. Translation: BAD59850.1 .
RefSeqi YP_121214.1. NC_006361.1.

3D structure databases

ProteinModelPortali Q5YPP1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 247156.nfa49980.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAD59850 ; BAD59850 ; NFA_49980 .
GeneIDi 3111365.
KEGGi nfa:nfa49980.
PATRICi 22739577. VBINocFar94200_5011.

Phylogenomic databases

eggNOGi COG0166.
KOi K01810.
OMAi HKILAAN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci NFAR247156:GJ9T-5066-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IFM 10152.

Entry informationi

Entry nameiG6PI_NOCFA
AccessioniPrimary (citable) accession number: Q5YPP1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: November 23, 2004
Last modified: October 29, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3