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Q5YPP1

- G6PI_NOCFA

UniProt

Q5YPP1 - G6PI_NOCFA

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Nocardia farcinica (strain IFM 10152)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (23 Nov 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei359 – 3591Proton donorUniRule annotation
    Active sitei390 – 3901UniRule annotation
    Active sitei516 – 5161UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciNFAR247156:GJ9T-5066-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:NFA_49980
    OrganismiNocardia farcinica (strain IFM 10152)
    Taxonomic identifieri247156 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeNocardia
    ProteomesiUP000006820: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 551551Glucose-6-phosphate isomerasePRO_0000180696Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi247156.nfa49980.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5YPP1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    KOiK01810.
    OMAiHKILAAN.
    OrthoDBiEOG64R61J.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5YPP1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSTLADVSSD ITASAAWRKL HDHHGALAQR HLREIFAEDP ERGRELTLQV    50
    ADLHIDYSKH RATRETLQLL VELAREAGVE AHRDAMFAGE HINTSEDRAV 100
    GHVALRLPAG RTMTIDGADA GAQVHEVLRR MGEFTDALRS GQWRGATGER 150
    IETVVNIGIG GSDLGPVMVH QALRHYADAG ITARFVSNVD PADLVAELTG 200
    LNPATTLFIV ASKTFSTLET LTNATAARRW LVAALGEDAV AKHFVAVSTN 250
    AERVSAFGID TANMFGFWDW VGGRYSVDSA IGLSVMATIG KERFAEFLAG 300
    MHAVDTHFAT APLEANAPVL LGLLGIWYAN FFGAESRAVL PYSNDLARFP 350
    AYLQQLTMES NGKSVRADGT PVTTATGEIF WGEPGTNGQH AFYQLLHQGT 400
    RLIPADFIGF ARPTDDLPTA DGTGSMHDVL MSNLFAQTKV LAFGKTAEEI 450
    AAEGTAPNLV PHKVMPGNRP STTILAPQLT PAVVGQLIAL YEHQVFVEGV 500
    IWGIDSFDQW GVELGKQQAL ALAALLTAAE DPAPQDDSST DALIRWYRAH 550
    R 551
    Length:551
    Mass (Da):59,471
    Last modified:November 23, 2004 - v1
    Checksum:iF22568B0F195B6EF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP006618 Genomic DNA. Translation: BAD59850.1.
    RefSeqiYP_121214.1. NC_006361.1.

    Genome annotation databases

    EnsemblBacteriaiBAD59850; BAD59850; NFA_49980.
    GeneIDi3111365.
    KEGGinfa:nfa49980.
    PATRICi22739577. VBINocFar94200_5011.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP006618 Genomic DNA. Translation: BAD59850.1 .
    RefSeqi YP_121214.1. NC_006361.1.

    3D structure databases

    ProteinModelPortali Q5YPP1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 247156.nfa49980.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAD59850 ; BAD59850 ; NFA_49980 .
    GeneIDi 3111365.
    KEGGi nfa:nfa49980.
    PATRICi 22739577. VBINocFar94200_5011.

    Phylogenomic databases

    eggNOGi COG0166.
    KOi K01810.
    OMAi HKILAAN.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci NFAR247156:GJ9T-5066-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: IFM 10152.

    Entry informationi

    Entry nameiG6PI_NOCFA
    AccessioniPrimary (citable) accession number: Q5YPP1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 29, 2005
    Last sequence update: November 23, 2004
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3