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Q5YNV8 (PSD_NOCFA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:NFA_52810
OrganismNocardia farcinica (strain IFM 10152) [Complete proteome] [HAMAP]
Taxonomic identifier247156 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Nocardia

Protein attributes

Sequence length237 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00664

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphatidylethanolamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncofactor binding

Inferred from electronic annotation. Source: InterPro

phosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 205205Phosphatidylserine decarboxylase beta chain By similarity
PRO_0000029791
Chain206 – 23732Phosphatidylserine decarboxylase alpha chain By similarity
PRO_0000029792

Sites

Site205 – 2062Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2061Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5YNV8 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: 223FFF86758DC075

FASTA23724,940
        10         20         30         40         50         60 
MARRPTPPGT PETTGVGHVV DLVRASIPPL HPAGLPFVAV PLAVAVAAGK RKWVRRAGLA 

        70         80         90        100        110        120 
TAAACAGFFR HPNRVPPNRP GVVVAPADGE IALVDTASPP AELGLGDQPL PRVSIFLSVL 

       130        140        150        160        170        180 
DVHVQRTPVS GVVREVRHQS GQFRSADLPE ASAVNERNSM LLETQSGQQI VVVQIAGLLA 

       190        200        210        220        230 
RRIVCDARVG DVLTIGDTYG LIRFGSRVDT YFPVGTELLV QPGQRTIGGE TVLATLS

« Hide

References

[1]"The complete genomic sequence of Nocardia farcinica IFM 10152."
Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K., Shiba T., Hattori M.
Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004) [PubMed: 15466710] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IFM 10152.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006618 Genomic DNA. Translation: BAD60133.1.
RefSeqYP_121497.1. NC_006361.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3111400.
GenomeReviewsGene locus NFA_52810 in contig AP006618_GR.
KEGGnfa:nfa52810.
NMPDRfig|247156.1.peg.5077.
PATRIC22740161. VBINocFar94200_5299.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG541103.
OMAIFMSVFN.
ProtClustDBPRK05305.

Enzyme and pathway databases

BioCycNFAR247156:NFA52810-MONOMER.

Family and domain databases

HAMAPMF_00664. PS_decarb_type3.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR004428. PtdSer_deCO2ase-related.
[Graphical view]
KOK01613.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00164. PS_decarb_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_NOCFA
AccessionPrimary (citable) accession number: Q5YNV8
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: November 23, 2004
Last modified: January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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