Q5YNG0 (DCD_NOCFA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	NFA_54290

Organism

Nocardia farcinica (strain IFM 10152) [Complete proteome] [HAMAP]

Taxonomic identifier

247156 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Nocardia › Nocardia farcinica

Protein attributes

Sequence length	199 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 199	199	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000009774

Sequences

	Sequence		Length	Mass (Da)
	Q5YNG0 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: FDA83FBFBFA3282F	FASTA	199	21,594
	10 20 30 40 50 60 MLLSDRDIRA EIAAGRLGVE PLLENLIQPS SIDVRLDRMF RVFDNSRYTH IDPAQRQDEL 70 80 90 100 110 120 TSLVEPGEGE PFVLHPGEFV LGSTLEVCTL PDDLAGRLEG KSSLGRLGLL THSTAGFIDP 130 140 150 160 170 180 GFSGHITLEL SNVANLPITL WPGMKIGQLC LFRLSSPAEH PYGSAAAGSK YQGQRGPTPS 190 RSYLNFPLPS DAVDAVESR

References

[1]

"The complete genomic sequence of Nocardia farcinica IFM 10152." Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K., Shiba T., Hattori M. Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IFM 10152.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006618 Genomic DNA. Translation: BAD60281.1.
RefSeq	YP_121645.1. NC_006361.1.
3D structure databases
HSSP	HSSP built from PDB template 1XS1 based on UniProtKB P28248.
ProteinModelPortal	Q5YNG0.
SMR	Q5YNG0. Positions 1-186.
ModBase	Search...
Protein-protein interaction databases
STRING	247156.nfa54290.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAD60281; BAD60281; NFA_54290.
GeneID	3109810.
KEGG	nfa:nfa54290.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
KO	K01494.
OMA	RQDAKYK.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	NFAR247156:GJ9T-5500-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_NOCFA

Accession

Primary (citable) accession number: Q5YNG0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	November 23, 2004
Last modified:	May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program