Q5YNG0 (DCD_NOCFA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	NFA_54290

Organism

Nocardia farcinica (strain IFM 10152) [Complete proteome] [HAMAP]

Taxonomic identifier

247156 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Nocardia

Protein attributes

Sequence length	199 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 199	199	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009774

Sequences

	Sequence		Length	Mass (Da)
	Q5YNG0 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: FDA83FBFBFA3282F	FASTA	199	21,594
	10 20 30 40 50 60 MLLSDRDIRA EIAAGRLGVE PLLENLIQPS SIDVRLDRMF RVFDNSRYTH IDPAQRQDEL 70 80 90 100 110 120 TSLVEPGEGE PFVLHPGEFV LGSTLEVCTL PDDLAGRLEG KSSLGRLGLL THSTAGFIDP 130 140 150 160 170 180 GFSGHITLEL SNVANLPITL WPGMKIGQLC LFRLSSPAEH PYGSAAAGSK YQGQRGPTPS 190 RSYLNFPLPS DAVDAVESR

References

[1]

"The complete genomic sequence of Nocardia farcinica IFM 10152." Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K., Shiba T., Hattori M. Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004) [PubMed: 15466710] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IFM 10152.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006618 Genomic DNA. Translation: BAD60281.1.
RefSeq	YP_121645.1. NC_006361.1.
3D structure databases
HSSP	HSSP built from PDB template 1XS1 based on UniProtKB P28248.
ProteinModelPortal	Q5YNG0.
SMR	Q5YNG0. Positions 1-186.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3109810.
GenomeReviews	Gene locus NFA_54290 in contig AP006618_GR.
KEGG	nfa:nfa54290.
NMPDR	fig|247156.1.peg.5217.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG553199.
OMA	HTAAYID.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	NFAR247156:NFA54290-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_NOCFA

Accession

Primary (citable) accession number: Q5YNG0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	November 23, 2004
Last modified:	December 14, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program