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Q5Y7D6 (Q5Y7D6_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 96. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

MHC class II antigen EMBL AAU88009.1

cDNA, FLJ79232, highly similar to HLA class II histocompatibility antigen, DQB1*0602 beta chain EMBL BAH14704.1
Gene names
Name:HLA-DQB1 Ensembl ENSP00000407332 EMBL AAU88009.1 Ensembl ENSP00000382034
OrganismHomo sapiens (Human) [Reference proteome] EMBL AAU88009.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length261 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains Ig-like C1-type (immunoglobulin-like) domain. SAAS SAAS014745

Sequences

Sequence LengthMass (Da)Tools
Q5Y7D6 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: 955BF0E22AA4BD79

FASTA26129,791
        10         20         30         40         50         60 
MSWKKALRIP GDLRVATVTL MLAMLSSLLA EGRDSPEDFV FQFKGMCYFT NGTERVRLVT 

        70         80         90        100        110        120 
RYIYNREEYA RFDSDVGVYR AVTPQGRPDA EYWNSQKEVL EGTRAELDTV CRHNYEVAFR 

       130        140        150        160        170        180 
GILQRRVEPT VTISPSRTEA LNHHNLLVCS VTDFYPGQIK VRWFRNDQEE TAGVVSTPLI 

       190        200        210        220        230        240 
RNGDWTFQIL VMLEMTPQRG DVYTCHVEHP SLQSPITVEW RAQSESAQSK MLSGVGGFVL 

       250        260 
GLIFLGLGLI IRQRSQKGLL H 

« Hide

References

« Hide 'large scale' references
[1]"The DNA sequence and analysis of human chromosome 6."
Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D. expand/collapse author list , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"Ancient haplotypes of the HLA Class II region."
Raymond C.K., Kas A., Paddock M., Qiu R., Zhou Y., Subramanian S., Chang J., Palmieri A., Haugen E., Kaul R., Olson M.V.
Genome Res. 15:1250-1257(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[3]"NEDO human cDNA sequencing project."
Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. expand/collapse author list , Sugano S., Nomura N., Isogai T.
Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Spleen EMBL BAH14704.1.
[4]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
[5]"Phase-defined complete sequencing of the HLA genes by next-generation sequencing."
Hosomichi K., Jinam T.A., Mitsunaga S., Nakaoka H., Inoue I.
BMC Genomics 14:355-355(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[6]"44 novel HLA-DQB1 alleles found by BGI in 2011 year."
Li J.
Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL662789 Genomic DNA. No translation available.
AY663395 Genomic DNA. Translation: AAU87980.1.
AY663406 Genomic DNA. Translation: AAU88009.1.
AY663411 Genomic DNA. Translation: AAU88024.1.
KF270555 Genomic DNA. Translation: AGW82949.2.
AK316333 mRNA. Translation: BAH14704.1.
AB774942 Genomic DNA. Translation: BAN59788.1.
AB774978 Genomic DNA. Translation: BAN59824.1.
RefSeqNP_002114.3. NM_002123.4.
UniGeneHs.409934.
Hs.534322.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

DNASU3119.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000399084; ENSP00000382034; ENSG00000179344.
ENST00000434651; ENSP00000407332; ENSG00000179344.
GeneID3119.
KEGGhsa:3119.
UCSCuc003obw.3. human.

Organism-specific databases

CTD3119.
HGNCHGNC:4944. HLA-DQB1.
PharmGKBPA35068.
GenAtlasSearch...

Phylogenomic databases

HOVERGENHBG012730.
KOK06752.
TreeFamTF336626.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
3.10.320.10. 1 hit.
InterProIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR000353. MHC_II_b_N.
[Graphical view]
PfamPF07654. C1-set. 1 hit.
PF00969. MHC_II_beta. 1 hit.
[Graphical view]
ProDomPD000328. MHC_II_b_N. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTSM00407. IGc1. 1 hit.
SM00921. MHC_II_beta. 1 hit.
[Graphical view]
SUPFAMSSF54452. SSF54452. 1 hit.
PROSITEPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSHLA-DQB1. human.
GenomeRNAi3119.
NextBio12380.

Entry information

Entry nameQ5Y7D6_HUMAN
AccessionPrimary (citable) accession number: Q5Y7D6
Entry history
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: April 16, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.