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Q5Y7D1 (Q5Y7D1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:HLA-DRB1 EMBL AAU88011.1
OrganismHomo sapiens (Human) EMBL AAU88011.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length266 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains Ig-like C1-type (immunoglobulin-like) domain. SAAS SAAS014745

Sequences

Sequence LengthMass (Da)Tools
Q5Y7D1 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: 37329B097C6BEEB4

FASTA26630,120
        10         20         30         40         50         60 
MVCLRLPGGS CMAVLTVTLM VLSSPLALAG DTRPRFLEYS TSECHFFNGT ERVRYLDRYF 

        70         80         90        100        110        120 
HNQEENVRFD SDVGEFRAVT ELGRPDAEYW NSQKDLLEQK RGRVDNYCRH NYGVVESFTV 

       130        140        150        160        170        180 
QRRVHPKVTV YPSKTQPLQH HNLLVCSVSG FYPGSIEVRW FRNGQEEKTG VVSTGLIHNG 

       190        200        210        220        230        240 
DWTFQTLVML ETVPRSGEVY TCQVEHPSVT SPLTVEWRAR SESAQSKMLS GVGGFVLGLL 

       250        260 
FLGAGLFIYF RNQKGHSGLQ PRGFLS 

« Hide

References

[1]"Ancient haplotypes of the HLA Class II region."
Raymond C.K., Kas A., Paddock M., Qiu R., Zhou Y., Subramanian S., Chang J., Palmieri A., Haugen E., Kaul R., Olson M.V.
Genome Res. 15:1250-1257(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[2]"Group-specific amplification of cDNA from DRB1 genes. Complete coding sequences of partially defined alleles and identification of the new alleles DRB1*040602, DRB1*111102, DRB1*080103, and DRB1*0113."
Balas A., Vilches C., Rodriguez M.A., Fernandez B., Martinez M.P., de Pablo R., Garcia-Sanchez F., Vicario J.L.
Hum. Immunol. 67:1008-1016(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[3]"Full length cDNA sequence of HLA-DRB1*03:01:01:01."
Zhu F.M., He Y.M., Yan L.X.
Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[4]"Analysis of the complete cDNA sequences of HLA-DRB1 alleles with group-specific amplification primers in the Chinese Han population."
Zhu F., He Y., Tao S., Zhang W., He J., He J., Xu X., Lv H., Yan L.
Tissue Antigens 77:329-332(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY663399 Genomic DNA. Translation: AAU87990.1.
AY663407 Genomic DNA. Translation: AAU88011.1.
AY961064 mRNA. Translation: AAX63452.1.
HM067844 mRNA. Translation: ADI59556.1.
RefSeqNP_001230894.1. NM_001243965.1.
UniGeneHs.534322.
Hs.696211.
Hs.716081.
Hs.723344.
Hs.736560.

3D structure databases

ProteinModelPortalQ5Y7D1.
SMRQ5Y7D1. Positions 34-220.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ5Y7D1.

Protocols and materials databases

DNASU3123.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3123.
KEGGhsa:3123.

Organism-specific databases

CTD3123.
H-InvDBHIX0005754.
HIX0078596.

Phylogenomic databases

HOVERGENHBG012730.
KOK06752.
OMAYSTSECY.
PhylomeDBQ5Y7D1.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
3.10.320.10. 1 hit.
InterProIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR000353. MHC_II_b_N.
[Graphical view]
PfamPF07654. C1-set. 1 hit.
PF00969. MHC_II_beta. 1 hit.
[Graphical view]
ProDomPD000328. MHC_II_b_N. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTSM00407. IGc1. 1 hit.
SM00921. MHC_II_beta. 1 hit.
[Graphical view]
SUPFAMSSF54452. SSF54452. 1 hit.
PROSITEPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSHLA-DRB1. human.
GenomeRNAi3123.
NextBio12394.

Entry information

Entry nameQ5Y7D1_HUMAN
AccessionPrimary (citable) accession number: Q5Y7D1
Entry history
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: April 16, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.