Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Duffy antigen/atypical chemokine receptor

Gene

FY

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Duffy antigen/atypical chemokine receptorImported
Submitted name:
Duffy antigen/chemokine receptor isoform bImported
Submitted name:
Duffy blood groupImported
Submitted name:
cDNA FLJ75122, highly similar to Homo sapiens Duffy blood group, chemokine receptor, mRNAImported
Gene namesi
Name:FYImported
Synonyms:DARCImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei62 – 8423HelicalSequence analysisAdd
BLAST
Transmembranei96 – 11621HelicalSequence analysisAdd
BLAST
Transmembranei136 – 15318HelicalSequence analysisAdd
BLAST
Transmembranei165 – 18622HelicalSequence analysisAdd
BLAST
Transmembranei206 – 22621HelicalSequence analysisAdd
BLAST
Transmembranei246 – 26621HelicalSequence analysisAdd
BLAST
Transmembranei286 – 30823HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28451.

Expressioni

Gene expression databases

BgeeiENSG00000213088.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000357103.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IHK3. Eukaryota.
ENOG41119V5. LUCA.
HOVERGENiHBG051419.
KOiK06574.
PhylomeDBiQ5Y7A2.

Family and domain databases

InterProiIPR005384. Duffy_chemokine_rcpt.
[Graphical view]
PANTHERiPTHR14181. PTHR14181. 1 hit.
PRINTSiPR01559. DUFFYANTIGEN.

Sequencei

Sequence statusi: Complete.

Q5Y7A2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNCLHRAEL SPSTENSSQL DFEDVWNSSY GVNDSFPDGD YGANLEAAAP
60 70 80 90 100
CHSCNLLDDS ALPFFILTSV LGILASSTVL FMLFRPLFRW QLCPGWPVLA
110 120 130 140 150
QLAVGSALFS IVVPVLAPGL GSTRSSALCS LGYCVWYGSA FAQALLLGCH
160 170 180 190 200
ASLGHRLGAG QVPGLTLGLT VGIWGVAALL TLPVTLASGA SGGLCTLIYS
210 220 230 240 250
TELKALQATH TVACLAIFVL LPLGLFGAKG LKKALGMGPG PWMNILWAWF
260 270 280 290 300
IFWWPHGVVL GLDFLVRSKL LLLSTCLAQQ ALDLLLNLAE ALAILHCVAT
310 320 330
PLLLALFCHQ ATRTLLPSLP LPEGWSSHLD TLGSKS
Length:336
Mass (Da):35,553
Last modified:May 10, 2005 - v1
Checksum:iC3F2A3E71D972E2D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY663418 Genomic DNA. Translation: AAU47281.1.
DQ181554 Genomic DNA. Translation: ABA10406.1.
DQ181556 Genomic DNA. Translation: ABA10412.1.
DQ181557 Genomic DNA. Translation: ABA10415.1.
DQ181558 Genomic DNA. Translation: ABA10418.1.
DQ181559 Genomic DNA. Translation: ABA10421.1.
DQ181560 Genomic DNA. Translation: ABA10424.1.
DQ181561 Genomic DNA. Translation: ABA10427.1.
DQ181562 Genomic DNA. Translation: ABA10430.1.
DQ181567 Genomic DNA. Translation: ABA10445.1.
JN251907 Genomic DNA. Translation: AET81018.1.
JN251908 Genomic DNA. Translation: AET81019.1.
JN251909 Genomic DNA. Translation: AET81021.1.
AK291593 mRNA. Translation: BAF84282.1.
LN715170 Genomic DNA. Translation: CEL12051.1.
RefSeqiNP_002027.2. NM_002036.3.
UniGeneiHs.153381.

Genome annotation databases

GeneIDi2532.
KEGGihsa:2532.
UCSCiuc001fto.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY663418 Genomic DNA. Translation: AAU47281.1.
DQ181554 Genomic DNA. Translation: ABA10406.1.
DQ181556 Genomic DNA. Translation: ABA10412.1.
DQ181557 Genomic DNA. Translation: ABA10415.1.
DQ181558 Genomic DNA. Translation: ABA10418.1.
DQ181559 Genomic DNA. Translation: ABA10421.1.
DQ181560 Genomic DNA. Translation: ABA10424.1.
DQ181561 Genomic DNA. Translation: ABA10427.1.
DQ181562 Genomic DNA. Translation: ABA10430.1.
DQ181567 Genomic DNA. Translation: ABA10445.1.
JN251907 Genomic DNA. Translation: AET81018.1.
JN251908 Genomic DNA. Translation: AET81019.1.
JN251909 Genomic DNA. Translation: AET81021.1.
AK291593 mRNA. Translation: BAF84282.1.
LN715170 Genomic DNA. Translation: CEL12051.1.
RefSeqiNP_002027.2. NM_002036.3.
UniGeneiHs.153381.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000357103.

Protocols and materials databases

DNASUi2532.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2532.
KEGGihsa:2532.
UCSCiuc001fto.4. human.

Organism-specific databases

CTDi2532.
PharmGKBiPA28451.

Phylogenomic databases

eggNOGiENOG410IHK3. Eukaryota.
ENOG41119V5. LUCA.
HOVERGENiHBG051419.
KOiK06574.
PhylomeDBiQ5Y7A2.

Miscellaneous databases

ChiTaRSiDARC. human.
GenomeRNAii2532.

Gene expression databases

BgeeiENSG00000213088.

Family and domain databases

InterProiIPR005384. Duffy_chemokine_rcpt.
[Graphical view]
PANTHERiPTHR14181. PTHR14181. 1 hit.
PRINTSiPR01559. DUFFYANTIGEN.
ProtoNetiSearch...

Entry informationi

Entry nameiQ5Y7A2_HUMAN
AccessioniPrimary (citable) accession number: Q5Y7A2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 7, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.