Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Death domain-associated protein

Gene

Daxx

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. androgen receptor binding Source: MGI
  2. enzyme binding Source: MGI
  3. histone binding Source: MGI
  4. p53 binding Source: MGI
  5. protein homodimerization activity Source: MGI
  6. protein kinase activator activity Source: MGI
  7. protein kinase binding Source: MGI
  8. protein N-terminus binding Source: MGI
  9. transcription corepressor activity Source: MGI
  10. transcription factor binding Source: MGI
  11. ubiquitin protein ligase binding Source: MGI

GO - Biological processi

  1. androgen receptor signaling pathway Source: MGI
  2. apoptotic signaling pathway Source: MGI
  3. chromatin remodeling Source: MGI
  4. mitotic cytokinesis Source: MGI
  5. negative regulation of transcription, DNA-templated Source: MGI
  6. nucleosome assembly Source: MGI
  7. positive regulation of apoptotic signaling pathway Source: MGI
  8. positive regulation of neuron death Source: MGI
  9. positive regulation of protein kinase activity Source: MGI
  10. positive regulation of protein phosphorylation Source: MGI
  11. regulation of protein ubiquitination Source: MGI
  12. regulation of transcription, DNA-templated Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Death domain-associated proteinImported
Gene namesi
Name:DaxxImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1197015. Daxx.

Subcellular locationi

GO - Cellular componenti

  1. heterochromatin Source: MGI
  2. nucleus Source: MGI
  3. PML body Source: MGI
  4. SWI/SNF superfamily-type complex Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ5XW57.
ExpressionAtlasiQ5XW57. baseline and differential.
GenevestigatoriQ5XW57.

Family & Domainsi

Family and domain databases

InterProiIPR005012. Daxx.
[Graphical view]
PANTHERiPTHR12766. PTHR12766. 1 hit.
PfamiPF03344. Daxx. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q5XW57-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
FGRLCELKDC SSLTGRVIEQ RIPYRGTRYP EVNRRIERLI NKPGLDTFPD
60 70 80 90 100
YGDVLRAVEK AATRHSLGLP RQQLQLLAQD AFRDVGVRLQ ERRHLDLIYN
110 120 130 140 150
FGCHLTDDYR PGVDPALSDP TLARRLRENR TLAMNRLDEV ISKYAMMQDK

TE
Length:152
Mass (Da):17,656
Last modified:November 23, 2004 - v1
Checksum:i14137176C5C8B379
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei152 – 1521Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY734462 mRNA. Translation: AAU50681.1.
UniGeneiMm.271809.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY734462 mRNA. Translation: AAU50681.1.
UniGeneiMm.271809.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1197015. Daxx.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiQ5XW57.
ExpressionAtlasiQ5XW57. baseline and differential.
GenevestigatoriQ5XW57.

Family and domain databases

InterProiIPR005012. Daxx.
[Graphical view]
PANTHERiPTHR12766. PTHR12766. 1 hit.
PfamiPF03344. Daxx. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "MHC-linked diabetes susceptibility in NOD/Lt mice: subcongenic analysis localizes a component of 'Idd16' at the H2-D end of the diabetogenic H2g7 complex."
    Leiter E.H., Pomerleau D.P.
    Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ALS/LtImported.

Entry informationi

Entry nameiQ5XW57_MOUSE
AccessioniPrimary (citable) accession number: Q5XW57
Entry historyi
Integrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: February 4, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.