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Q5XW54

- Q5XW54_MOUSE

UniProt

Q5XW54 - Q5XW54_MOUSE

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Protein
Submitted name:

Death domain-associated protein

Gene

Daxx

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. protein kinase activator activity Source: Ensembl
  2. transcription corepressor activity Source: Ensembl

GO - Biological processi

  1. androgen receptor signaling pathway Source: Ensembl
  2. apoptotic signaling pathway Source: MGI
  3. chromatin remodeling Source: Ensembl
  4. mitotic cytokinesis Source: MGI
  5. negative regulation of transcription, DNA-templated Source: MGI
  6. nucleosome assembly Source: Ensembl
  7. positive regulation of apoptotic signaling pathway Source: MGI
  8. positive regulation of neuron death Source: Ensembl
  9. regulation of protein ubiquitination Source: Ensembl
  10. regulation of transcription, DNA-templated Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Death domain-associated proteinImported
Gene namesi
Name:DaxxImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1197015. Daxx.

Subcellular locationi

GO - Cellular componenti

  1. heterochromatin Source: MGI
  2. nucleus Source: MGI
  3. PML body Source: MGI
  4. SWI/SNF superfamily-type complex Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ5XW54.
ExpressionAtlasiQ5XW54. baseline and differential.
GenevestigatoriQ5XW54.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG031495.

Family and domain databases

InterProiIPR005012. Daxx.
[Graphical view]
PANTHERiPTHR12766. PTHR12766. 1 hit.
PfamiPF03344. Daxx. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q5XW54-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
LARSRKRPAK IYVYINELCT VLKAHSIKKK LNLAPAASTT SEASGPNPPT
60 70 80 90 100
EPPSDLTNTE NTASEASRTR GSRRQIQRLE QLLALYVAEI RRLQEKELDL
110 120 130 140 150
SELDDPDSSY LQEARLKRKL IRLFGRLCEL KDCSSLTGRV IEQRIPYRGT
160 170 180 190 200
RYPEVNRRIE RLINKPGLDT FPDYGDVLRA VEKAATRHSL GLPRQQLQLL
210 220 230 240 250
AQDAFRDVGV RLQERRHLDL IYNFGCHLTD DYRPGVDPAL SDPTLARRLR
260 270 280 290 300
ENRTLAMNRL DEVISKYAMM QDKTEEGERQ KRRARLLGTA PQPSDPPKAS
310 320 330 340 350
SESGEGPSGM ASQECPTTSK AETDDDDDDD DDDDEDNEES EEEEEEEEEE
360 370 380 390 400
KEATEDEDED LEQLQEDQGG DEEEEGGDNE GNESPTSPSD FFHRRNSEPA
410 420 430 440 450
EGLRTPEGQQ KRGLTETPAS PPGASLDPPS TDAESSGEQL LEPLLGDESP
460 470 480 490 500
VSQLAELEME ALPEERDISS SRKKSEDSLP TILENGAAVV TSTSVNGRVS
510 520 530 540 550
SHTWRDASPP SKRFRKEKKQ LGSGLLGNSY IKEPMAQQDS GQNTSVQPMP
560 570 580 590 600
SPPLASVASV ADSSTRVDSP SHELVTSSLC SPSPSLLLQT PQAQSLRQCI
610 620
YKTSVATQCD PEEIIVLSDS D
Length:621
Mass (Da):68,821
Last modified:November 23, 2004 - v1
Checksum:i6886862411DF458A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY734465 mRNA. Translation: AAU45095.1.
UniGeneiMm.271809.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY734465 mRNA. Translation: AAU45095.1 .
UniGenei Mm.271809.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:1197015. Daxx.

Phylogenomic databases

HOVERGENi HBG031495.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Bgeei Q5XW54.
ExpressionAtlasi Q5XW54. baseline and differential.
Genevestigatori Q5XW54.

Family and domain databases

InterProi IPR005012. Daxx.
[Graphical view ]
PANTHERi PTHR12766. PTHR12766. 1 hit.
Pfami PF03344. Daxx. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "MHC-linked diabetes susceptibility in NOD/Lt mice: subcongenic analysis localizes a component of 'Idd16' at the H2-D end of the diabetogenic H2g7 complex."
    Leiter E.H., Pomerleau D.P.
    Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CTS/ShiLtImported.

Entry informationi

Entry nameiQ5XW54_MOUSE
AccessioniPrimary (citable) accession number: Q5XW54
Entry historyi
Integrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: October 29, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)