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Protein
Submitted name:

Parkin

Gene

PARK2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ubiquitin-protein transferase activity Source: Ensembl

GO - Biological processi

  1. adult locomotory behavior Source: Ensembl
  2. cellular protein catabolic process Source: Ensembl
  3. dopamine metabolic process Source: Ensembl
  4. dopamine uptake involved in synaptic transmission Source: Ensembl
  5. learning Source: Ensembl
  6. norepinephrine metabolic process Source: Ensembl
  7. regulation of neurotransmitter secretion Source: Ensembl
  8. startle response Source: Ensembl
  9. synaptic transmission, glutamatergic Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
ParkinImported
Gene namesi
Name:PARK2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. neuron projection Source: Ensembl
  2. nucleus Source: Ensembl
  3. protein complex Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ5XNR7.
ExpressionAtlasiQ5XNR7. baseline and differential.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000013184.

Sequencei

Sequence statusi: Fragment.

Q5XNR7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
NCDLDQQSIV HIVQRPWRKG QEMNATGGDD PRNAAGGCER EPQSLTRVDL
60 70 80
SSSVLPGDSV GLAVILHTDS RKDSPPAGSP
Length:80
Mass (Da):8,492
Last modified:November 23, 2004 - v1
Checksum:i07B9BD9641AC50C3
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei80 – 801Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY745247 Genomic DNA. Translation: AAU93632.1.
DQ019286 Genomic DNA. Translation: AAY85310.1.
UniGeneiHs.132954.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY745247 Genomic DNA. Translation: AAU93632.1.
DQ019286 Genomic DNA. Translation: AAY85310.1.
UniGeneiHs.132954.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOGENOMiHOG000013184.

Gene expression databases

BgeeiQ5XNR7.
ExpressionAtlasiQ5XNR7. baseline and differential.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. Zou H.-Q., Chan P.
    Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "IVS2-18T>A, a novel single nucleotide polymorphism in the intronic region of human Parkin gene."
    Chaudhary S., Thelma B.K., Juyal R.C.
    Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ5XNR7_HUMAN
AccessioniPrimary (citable) accession number: Q5XNR7
Entry historyi
Integrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: October 29, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.