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Protein

Transmembrane protein 56-B

Gene

tmem56b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 56-B
Gene namesi
Name:tmem56b
Synonyms:tmem56
ORF Names:zgc:92864
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 3

Organism-specific databases

ZFINiZDB-GENE-041010-90. tmem56b.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei6 – 2621HelicalSequence analysisAdd
BLAST
Transmembranei50 – 7021HelicalSequence analysisAdd
BLAST
Transmembranei84 – 10421HelicalSequence analysisAdd
BLAST
Transmembranei110 – 13021HelicalSequence analysisAdd
BLAST
Transmembranei169 – 18921HelicalSequence analysisAdd
BLAST
Transmembranei210 – 23021HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 264264Transmembrane protein 56-BPRO_0000286703Add
BLAST

Proteomic databases

PaxDbiQ5XIY2.

Expressioni

Gene expression databases

BgeeiENSDARG00000043595.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000112952.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini41 – 243203TLCPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the TMEM56 family.Curated
Contains 1 TLC (TRAM/LAG1/CLN8) domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4561. Eukaryota.
ENOG410XPW0. LUCA.
GeneTreeiENSGT00510000047701.
HOGENOMiHOG000007105.
InParanoidiQ5XIY2.
OMAiVAWIVSC.
OrthoDBiEOG091G0RUV.
PhylomeDBiQ5XIY2.
TreeFamiTF324847.

Family and domain databases

InterProiIPR006634. TLC-dom.
[Graphical view]
PfamiPF03798. TRAM_LAG1_CLN8. 1 hit.
[Graphical view]
SMARTiSM00724. TLC. 1 hit.
[Graphical view]
PROSITEiPS50922. TLC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5XIY2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDMREVYVVA GSFVGFQLFF SCVSPVLSSN FTQGYGKLPP NKLNDWNSRL
60 70 80 90 100
VSTVHALIVG LFCLYILWYD DAVNEDPVWG DPNLVKLNVA ITCGYLFYDL
110 120 130 140 150
LLLACNWSTM GDVFFVCHHL AALYAYGYVL TRGVLPYFAN FRLISELSTP
160 170 180 190 200
FVNQRWFFEA LAYPRTHQLV VANGIAMAVV FFLVRIAVMP PYWAKVFGII
210 220 230 240 250
YSPTFEKLGL AIQVAWIISC VCLDILNIIW MYKIARGCYK VITGKLKGRK
260
ADSKKTTCVN NHTD
Length:264
Mass (Da):29,927
Last modified:November 23, 2004 - v1
Checksum:i52EDD3FB9279DF55
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC083537 mRNA. Translation: AAH83537.1.
RefSeqiNP_001005924.1. NM_001005924.1.
XP_005168534.1. XM_005168477.2.
UniGeneiDr.87204.

Genome annotation databases

EnsembliENSDART00000165452; ENSDARP00000130550; ENSDARG00000098224.
ENSDART00000171726; ENSDARP00000133377; ENSDARG00000098224.
GeneIDi449652.
KEGGidre:449652.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC083537 mRNA. Translation: AAH83537.1.
RefSeqiNP_001005924.1. NM_001005924.1.
XP_005168534.1. XM_005168477.2.
UniGeneiDr.87204.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000112952.

Proteomic databases

PaxDbiQ5XIY2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000165452; ENSDARP00000130550; ENSDARG00000098224.
ENSDART00000171726; ENSDARP00000133377; ENSDARG00000098224.
GeneIDi449652.
KEGGidre:449652.

Organism-specific databases

CTDi449652.
ZFINiZDB-GENE-041010-90. tmem56b.

Phylogenomic databases

eggNOGiKOG4561. Eukaryota.
ENOG410XPW0. LUCA.
GeneTreeiENSGT00510000047701.
HOGENOMiHOG000007105.
InParanoidiQ5XIY2.
OMAiVAWIVSC.
OrthoDBiEOG091G0RUV.
PhylomeDBiQ5XIY2.
TreeFamiTF324847.

Miscellaneous databases

PROiQ5XIY2.

Gene expression databases

BgeeiENSDARG00000043595.

Family and domain databases

InterProiIPR006634. TLC-dom.
[Graphical view]
PfamiPF03798. TRAM_LAG1_CLN8. 1 hit.
[Graphical view]
SMARTiSM00724. TLC. 1 hit.
[Graphical view]
PROSITEiPS50922. TLC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTM56B_DANRE
AccessioniPrimary (citable) accession number: Q5XIY2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: November 23, 2004
Last modified: September 7, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.