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Protein
Submitted name:

Baculoviral IAP repeat-containing 3

Gene

Birc3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • negative regulation of apoptotic process Source: RGD
  • spermatogenesis Source: RGD

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-RNO-168638 NOD1/2 Signaling Pathway
R-RNO-5213460 RIPK1-mediated regulated necrosis
R-RNO-5357905 Regulation of TNFR1 signaling
R-RNO-5357956 TNFR1-induced NFkappaB signaling pathway
R-RNO-5668541 TNFR2 non-canonical NF-kB pathway
R-RNO-5675482 Regulation of necroptotic cell death
R-RNO-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
R-RNO-5689880 Ub-specific processing proteases

Protein family/group databases

MEROPSiI32.003

Names & Taxonomyi

Protein namesi
Submitted name:
Baculoviral IAP repeat-containing 3Imported
Gene namesi
Name:Birc3Imported
ORF Names:rCG_31624Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi621282 Birc3

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSRNOG00000005731
ExpressionAtlasiQ5XIW4 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini438 – 527CARDInterPro annotationAdd BLAST90
Domaini555 – 590RING-typeInterPro annotationAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili419 – 439Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1101 Eukaryota
ENOG410YPNM LUCA
GeneTreeiENSGT00500000044782
HOGENOMiHOG000232059
HOVERGENiHBG004848
KOiK16060
TreeFamiTF105356

Family and domain databases

CDDicd00022 BIR, 3 hits
InterProiView protein in InterPro
IPR001370 BIR_rpt
IPR001315 CARD
IPR011029 DEATH-like_dom_sf
IPR001841 Znf_RING
PfamiView protein in Pfam
PF00653 BIR, 3 hits
PF00619 CARD, 1 hit
SMARTiView protein in SMART
SM00238 BIR, 3 hits
SM00114 CARD, 1 hit
SM00184 RING, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
PROSITEiView protein in PROSITE
PS01282 BIR_REPEAT_1, 3 hits
PS50143 BIR_REPEAT_2, 3 hits
PS50209 CARD, 1 hit
PS50089 ZF_RING_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5XIW4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNMVQGSAFL AKLMKSADTF ELKYDFSCEL YRLSTYSTFP AGVPVSERSL
60 70 80 90 100
ARAGFYYTGV NDKVKCFSCG LMLDNWKQGD SPIEKHRKLY PSCSFVQTLN
110 120 130 140 150
PANSLEASPQ PPLPSTATST MPSGFAASES TGYFSGSYSS FPSDPVNFRA
160 170 180 190 200
NQDCPAFSTS PYHFAMNTEK ARLLTYQTWP LSFLSPAELA KAGFYYTGPG
210 220 230 240 250
DRVACFACGG KLSNWDRKDD PLSEHRRHFP SCPFLKDVGQ FTSQYTVSNL
260 270 280 290 300
SMQTHAARVR TFSTWPSSAL VHPQELASAG FYYTGHSDDV KCFCCDGGLR
310 320 330 340 350
CWESGDDPWV EHAKWFPRCE YLIRIKGQEF VGQVQAGYPH LLEQLLSTSD
360 370 380 390 400
SPEDETGEAA IVHLGPGENW EDAVMMNTPV VKAALDMGFS RSLVRQTVQR
410 420 430 440 450
QILATGENYR TVSDLVIGLL DAEDEMREEQ TEQEAEEEES DDLTLIRKNK
460 470 480 490 500
MVLLQHLTPV TPILDCLLSA RVITEQEYDA VKQKPHTLQA RTLIDTVLAK
510 520 530 540 550
GNTAATSFRN SLQEIDPGLY RDIFVRQNIR SLPTDDIAAL PMEEQLRKLQ
560 570 580 590 600
EERTCKVCMD REVSLVFIPC GHLVVCKECA PSLRKCPICR GTIKGTVRTF

LS
Length:602
Mass (Da):67,280
Last modified:November 23, 2004 - v1
Checksum:i42AB05AA79873F01
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07069023 Genomic DNA No translation available.
BC083555 mRNA Translation: AAH83555.1
CH473993 Genomic DNA Translation: EDL78521.1
RefSeqiNP_076477.3, NM_023987.3
XP_006242564.1, XM_006242502.3
XP_006242565.1, XM_006242503.3
UniGeneiRn.64578

Genome annotation databases

EnsembliENSRNOT00000090774; ENSRNOP00000068729; ENSRNOG00000005731
GeneIDi78971
KEGGirno:78971

Similar proteinsi

Entry informationi

Entry nameiQ5XIW4_RAT
AccessioniPrimary (citable) accession number: Q5XIW4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: May 23, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health