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Protein
Submitted name:

Baculoviral IAP repeat-containing 3

Gene

Birc3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-RNO-5213460. RIPK1-mediated regulated necrosis.
R-RNO-5357905. Regulation of TNFR1 signaling.
R-RNO-5357956. TNFR1-induced NFkappaB signaling pathway.
R-RNO-5668541. TNFR2 non-canonical NF-kB pathway.
R-RNO-5675482. Regulation of necroptotic cell death.
R-RNO-5676594. TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway.
R-RNO-5689880. Ub-specific processing proteases.

Protein family/group databases

MEROPSiI32.003.

Names & Taxonomyi

Protein namesi
Submitted name:
Baculoviral IAP repeat-containing 3Imported
Gene namesi
Name:Birc3Imported
ORF Names:rCG_31624Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi621282. Birc3.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000005731.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini438 – 527CARDInterPro annotationAdd BLAST90
Domaini555 – 590RING-typeInterPro annotationAdd BLAST36

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1101. Eukaryota.
ENOG410YPNM. LUCA.
GeneTreeiENSGT00500000044782.
HOGENOMiHOG000232059.
HOVERGENiHBG004848.
KOiK16060.
TreeFamiTF105356.

Family and domain databases

CDDicd00022. BIR. 3 hits.
Gene3Di3.30.40.10. 1 hit.
InterProiView protein in InterPro
IPR001370. BIR_rpt.
IPR001315. CARD.
IPR011029. DEATH-like_dom_sf.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
PfamiView protein in Pfam
PF00653. BIR. 3 hits.
PF00619. CARD. 1 hit.
SMARTiView protein in SMART
SM00238. BIR. 3 hits.
SM00114. CARD. 1 hit.
SM00184. RING. 1 hit.
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiView protein in PROSITE
PS01282. BIR_REPEAT_1. 3 hits.
PS50143. BIR_REPEAT_2. 3 hits.
PS50209. CARD. 1 hit.
PS50089. ZF_RING_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5XIW4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNMVQGSAFL AKLMKSADTF ELKYDFSCEL YRLSTYSTFP AGVPVSERSL
60 70 80 90 100
ARAGFYYTGV NDKVKCFSCG LMLDNWKQGD SPIEKHRKLY PSCSFVQTLN
110 120 130 140 150
PANSLEASPQ PPLPSTATST MPSGFAASES TGYFSGSYSS FPSDPVNFRA
160 170 180 190 200
NQDCPAFSTS PYHFAMNTEK ARLLTYQTWP LSFLSPAELA KAGFYYTGPG
210 220 230 240 250
DRVACFACGG KLSNWDRKDD PLSEHRRHFP SCPFLKDVGQ FTSQYTVSNL
260 270 280 290 300
SMQTHAARVR TFSTWPSSAL VHPQELASAG FYYTGHSDDV KCFCCDGGLR
310 320 330 340 350
CWESGDDPWV EHAKWFPRCE YLIRIKGQEF VGQVQAGYPH LLEQLLSTSD
360 370 380 390 400
SPEDETGEAA IVHLGPGENW EDAVMMNTPV VKAALDMGFS RSLVRQTVQR
410 420 430 440 450
QILATGENYR TVSDLVIGLL DAEDEMREEQ TEQEAEEEES DDLTLIRKNK
460 470 480 490 500
MVLLQHLTPV TPILDCLLSA RVITEQEYDA VKQKPHTLQA RTLIDTVLAK
510 520 530 540 550
GNTAATSFRN SLQEIDPGLY RDIFVRQNIR SLPTDDIAAL PMEEQLRKLQ
560 570 580 590 600
EERTCKVCMD REVSLVFIPC GHLVVCKECA PSLRKCPICR GTIKGTVRTF

LS
Length:602
Mass (Da):67,280
Last modified:November 23, 2004 - v1
Checksum:i42AB05AA79873F01
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07069023 Genomic DNA. No translation available.
BC083555 mRNA. Translation: AAH83555.1.
CH473993 Genomic DNA. Translation: EDL78521.1.
RefSeqiNP_076477.3. NM_023987.3.
XP_006242564.1. XM_006242502.3.
XP_006242565.1. XM_006242503.3.
UniGeneiRn.64578.

Genome annotation databases

EnsembliENSRNOT00000090774; ENSRNOP00000068729; ENSRNOG00000005731.
GeneIDi78971.
KEGGirno:78971.

Similar proteinsi

Entry informationi

Entry nameiQ5XIW4_RAT
AccessioniPrimary (citable) accession number: Q5XIW4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: November 22, 2017
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported