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Q5XIU3

- Q5XIU3_RAT

UniProt

Q5XIU3 - Q5XIU3_RAT

Protein
Submitted name:

Protein Zbtb17

Gene

Zbtb17

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 94 (01 Oct 2014)
      Sequence version 1 (23 Nov 2004)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. DNA binding Source: Ensembl
    2. metal ion binding Source: UniProtKB-KW
    3. sequence-specific DNA binding transcription factor activity Source: Ensembl

    GO - Biological processi

    1. ectoderm development Source: Ensembl
    2. gastrulation with mouth forming second Source: Ensembl
    3. positive regulation of transcription, DNA-templated Source: Ensembl

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    ReactomeiREACT_93415. XBP1(S) activates chaperone genes.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein Zbtb17Imported
    Submitted name:
    Zinc finger and BTB domain containing 17Imported
    Gene namesi
    Name:Zbtb17Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 5

    Organism-specific databases

    RGDi1307143. Zbtb17.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-KW

    Keywords - Cellular componenti

    NucleusSAAS annotation

    Expressioni

    Gene expression databases

    GenevestigatoriQ5XIU3.

    Interactioni

    Protein-protein interaction databases

    STRINGi10116.ENSRNOP00000014399.

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 BTB (POZ) domain.UniRule annotation
    Contains BTB (POZ) domain.SAAS annotation

    Keywords - Domaini

    RepeatSAAS annotation, Zinc-fingerSAAS annotation

    Phylogenomic databases

    eggNOGiCOG5048.
    GeneTreeiENSGT00750000117570.
    HOGENOMiHOG000231298.
    HOVERGENiHBG054919.
    InParanoidiQ5XIU3.
    KOiK10500.
    OMAiCDSCGDK.
    OrthoDBiEOG7KSX7Q.
    TreeFamiTF332047.

    Family and domain databases

    Gene3Di3.30.160.60. 13 hits.
    3.30.710.10. 1 hit.
    InterProiIPR000210. BTB/POZ-like.
    IPR011333. BTB/POZ_fold.
    IPR013069. BTB_POZ.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view]
    PfamiPF00651. BTB. 1 hit.
    PF00096. zf-C2H2. 1 hit.
    [Graphical view]
    SMARTiSM00225. BTB. 1 hit.
    SM00355. ZnF_C2H2. 13 hits.
    [Graphical view]
    SUPFAMiSSF54695. SSF54695. 1 hit.
    PROSITEiPS50097. BTB. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 13 hits.
    PS50157. ZINC_FINGER_C2H2_2. 13 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5XIU3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDFPQHSQRV LEQLNQQRQM GLLCDCTFVV DGVDFKAHKA VLAACSEYFK    50
    MLFVDQKDVV HLDISNAAGL GQVLEFMYTA KLHLSPENVD DVLAVASFLQ 100
    MQDIITACHT LKSLAEPTST TGESADASAE EVCCVLSPGG DKRAKEEKAA 150
    ATVLSRLDQA RSSSSAGPGR ELKEEWGGQA ESASRGAEQT EKADAPREPP 200
    PVELKPDPTS SMAAAEAEAL SESSEQEMEV EPASKGEEGQ EEEGPGPATV 250
    KEEGVHLENG EPPEENEESA GTDSGHELGM EGQNLRSGTY GDRTESKAYG 300
    SIIHKCEDCG KEFTHTGNFK RHIRIHTGEK PFSCRECSKA FSDPAACKAH 350
    EKTHSPLKPY GCEECGKSYR LISLLNLHKK RHSGEARYRC GDCGKLFTTS 400
    GNLKRHQLVH SGQKPYQCDY CGRSFSDPTS KMRHLETHDT DKEHKCPHCD 450
    KKFNQVGNLK AHLKIHIADG PLKCRECGKQ FTTSGNLKRH LRIHSGEKPY 500
    VCTHCQRQFA DPGALQRHVR IHTGEKPCQC VICGKAFTQA SSLIAHVRQH 550
    TGEKPYVCER CGKRFVQSSQ LANHIRHHDN IRPHKCSVCS KAFVNVGDLS 600
    KHIIIHTGEK PYLCDKCGRG FNRVDNLRSH VKTVHQGKAG IKILEPEEGG 650
    EVSVVTVDDM VTLATEALAA TAVTQLTVVP VGAAVTADET EVLKAEISKA 700
    VKQVQEEDPN THILYACDSC GDKFLDANSL AQHVRIHTAQ ALVMFQTDAD 750
    FYQQYGPGGA WPAGQMLQAG ELVFRPRDGT EGQPTLAETP PTAPDCLPPA 800
    E 801
    Length:801
    Mass (Da):87,652
    Last modified:November 23, 2004 - v1
    Checksum:i774434964EE3E11F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06040715 Genomic DNA. No translation available.
    AABR06040716 Genomic DNA. No translation available.
    BC083577 mRNA. Translation: AAH83577.1.
    RefSeqiNP_001012105.1. NM_001012105.1.
    UniGeneiRn.15582.

    Genome annotation databases

    EnsembliENSRNOT00000014399; ENSRNOP00000014399; ENSRNOG00000010436.
    GeneIDi313666.
    KEGGirno:313666.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06040715 Genomic DNA. No translation available.
    AABR06040716 Genomic DNA. No translation available.
    BC083577 mRNA. Translation: AAH83577.1 .
    RefSeqi NP_001012105.1. NM_001012105.1.
    UniGenei Rn.15582.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10116.ENSRNOP00000014399.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000014399 ; ENSRNOP00000014399 ; ENSRNOG00000010436 .
    GeneIDi 313666.
    KEGGi rno:313666.

    Organism-specific databases

    CTDi 7709.
    RGDi 1307143. Zbtb17.

    Phylogenomic databases

    eggNOGi COG5048.
    GeneTreei ENSGT00750000117570.
    HOGENOMi HOG000231298.
    HOVERGENi HBG054919.
    InParanoidi Q5XIU3.
    KOi K10500.
    OMAi CDSCGDK.
    OrthoDBi EOG7KSX7Q.
    TreeFami TF332047.

    Enzyme and pathway databases

    Reactomei REACT_93415. XBP1(S) activates chaperone genes.

    Miscellaneous databases

    NextBioi 666628.
    PROi Q5XIU3.

    Gene expression databases

    Genevestigatori Q5XIU3.

    Family and domain databases

    Gene3Di 3.30.160.60. 13 hits.
    3.30.710.10. 1 hit.
    InterProi IPR000210. BTB/POZ-like.
    IPR011333. BTB/POZ_fold.
    IPR013069. BTB_POZ.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view ]
    Pfami PF00651. BTB. 1 hit.
    PF00096. zf-C2H2. 1 hit.
    [Graphical view ]
    SMARTi SM00225. BTB. 1 hit.
    SM00355. ZnF_C2H2. 13 hits.
    [Graphical view ]
    SUPFAMi SSF54695. SSF54695. 1 hit.
    PROSITEi PS50097. BTB. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 13 hits.
    PS50157. ZINC_FINGER_C2H2_2. 13 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: TestisImported.
    2. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiQ5XIU3_RAT
    AccessioniPrimary (citable) accession number: Q5XIU3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 23, 2004
    Last sequence update: November 23, 2004
    Last modified: October 1, 2014
    This is version 94 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3