Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

CTD small phosphatase-like protein 2

Gene

Ctdspl2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Probable phosphatase.By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
CTD small phosphatase-like protein 2 (EC:3.1.3.-)
Short name:
CTDSP-like 2
Gene namesi
Name:Ctdspl2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1309219. Ctdspl2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 465465CTD small phosphatase-like protein 2PRO_0000331466Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei26 – 261N6-acetyllysineBy similarity
Modified residuei28 – 281PhosphoserineCombined sources
Modified residuei51 – 511PhosphoserineBy similarity
Modified residuei57 – 571N6-acetyllysineBy similarity
Modified residuei85 – 851PhosphoserineBy similarity
Modified residuei86 – 861PhosphothreonineBy similarity
Modified residuei104 – 1041PhosphoserineBy similarity
Modified residuei134 – 1341PhosphoserineBy similarity
Modified residuei165 – 1651PhosphoserineBy similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiQ5XIK8.

PTM databases

iPTMnetiQ5XIK8.
PhosphoSiteiQ5XIK8.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000033786.

Structurei

3D structure databases

ProteinModelPortaliQ5XIK8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini282 – 441160FCP1 homologyPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the CTDSPL2 family.Curated
Contains 1 FCP1 homology domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1605. Eukaryota.
COG5190. LUCA.
HOGENOMiHOG000236379.
HOVERGENiHBG107781.
InParanoidiQ5XIK8.
KOiK17616.
PhylomeDBiQ5XIK8.

Family and domain databases

Gene3Di3.40.50.1000. 1 hit.
InterProiIPR011948. Dullard_phosphatase.
IPR004274. FCP1_dom.
IPR023214. HAD-like_dom.
[Graphical view]
PfamiPF03031. NIF. 1 hit.
[Graphical view]
SMARTiSM00577. CPDc. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR02251. HIF-SF_euk. 1 hit.
PROSITEiPS50969. FCP1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5XIK8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLRTRKASQ QSSPIQTQRT ARAKRKYSEV DDSLPSGGEK PSKNETGLLS
60 70 80 90 100
SIKKFIKGST PKEERENPSK RSRIERDIDN NLITSTPRTG EKPDKQLSRV
110 120 130 140 150
RRKSPVNGEA GSYEMTNQHI KQNGKLEDNP CSGSPPRTTL LGTIFSPVFN
160 170 180 190 200
FFSPANKNGT SGSDSPGQAV EAEEIVKQLD MEQVDEITTS TTSANGAAYS
210 220 230 240 250
NQAVQVRPSL NNGLEEAEET VTRDIPPLTA PVAPESGYSS AHAEATYEED
260 270 280 290 300
WEVFDPYYFI KHVPPLTEEQ LNRKPALPLK TRSTPEFSLV LDLDETLVHC
310 320 330 340 350
SLNELEDAAL TFPVLFQDVI YQVYVRLRPF FREFLERMSQ MYEIILFTAS
360 370 380 390 400
KKVYADKLLN ILDPKKQLVR HRLFREHCVC VQGNYIKDLN ILGRDLSKTI
410 420 430 440 450
IIDNSPQAFA YQLSNGIPIE SWFMDKNDNE LLKLIPFLEK LVELNEDVRP
460
HIRDRFRLHD LLPPD
Length:465
Mass (Da):52,783
Last modified:November 23, 2004 - v1
Checksum:i37589AEB721874BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC083672 mRNA. Translation: AAH83672.1.
RefSeqiNP_001014070.1. NM_001014048.1.
UniGeneiRn.230431.

Genome annotation databases

GeneIDi311368.
KEGGirno:311368.
UCSCiRGD:1309219. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC083672 mRNA. Translation: AAH83672.1.
RefSeqiNP_001014070.1. NM_001014048.1.
UniGeneiRn.230431.

3D structure databases

ProteinModelPortaliQ5XIK8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000033786.

PTM databases

iPTMnetiQ5XIK8.
PhosphoSiteiQ5XIK8.

Proteomic databases

PaxDbiQ5XIK8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi311368.
KEGGirno:311368.
UCSCiRGD:1309219. rat.

Organism-specific databases

CTDi51496.
RGDi1309219. Ctdspl2.

Phylogenomic databases

eggNOGiKOG1605. Eukaryota.
COG5190. LUCA.
HOGENOMiHOG000236379.
HOVERGENiHBG107781.
InParanoidiQ5XIK8.
KOiK17616.
PhylomeDBiQ5XIK8.

Miscellaneous databases

PROiQ5XIK8.

Family and domain databases

Gene3Di3.40.50.1000. 1 hit.
InterProiIPR011948. Dullard_phosphatase.
IPR004274. FCP1_dom.
IPR023214. HAD-like_dom.
[Graphical view]
PfamiPF03031. NIF. 1 hit.
[Graphical view]
SMARTiSM00577. CPDc. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR02251. HIF-SF_euk. 1 hit.
PROSITEiPS50969. FCP1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.
  2. "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues."
    Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C., Olsen J.V.
    Nat. Commun. 3:876-876(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-28, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiCTSL2_RAT
AccessioniPrimary (citable) accession number: Q5XIK8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: November 23, 2004
Last modified: July 6, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.