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Protein

Complement C1q tumor necrosis factor-related protein 1

Gene

C1qtnf1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Complement C1q tumor necrosis factor-related protein 1
Gene namesi
Name:C1qtnf1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1359204. C1qtnf1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_000032008226 – 281Complement C1q tumor necrosis factor-related protein 1Add BLAST256

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi93N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ5XIG2.
PRIDEiQ5XIG2.

Expressioni

Gene expression databases

BgeeiENSRNOG00000003259.
ExpressionAtlasiQ5XIG2. baseline and differential.
GenevisibleiQ5XIG2. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000004373.

Structurei

3D structure databases

ProteinModelPortaliQ5XIG2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini99 – 140Collagen-likeAdd BLAST42
Domaini141 – 281C1qPROSITE-ProRule annotationAdd BLAST141

Sequence similaritiesi

Contains 1 C1q domain.PROSITE-ProRule annotation
Contains 1 collagen-like domain.Curated

Keywords - Domaini

Collagen, Signal

Phylogenomic databases

eggNOGiENOG410IKX5. Eukaryota.
ENOG410XQIM. LUCA.
GeneTreeiENSGT00760000118830.
HOGENOMiHOG000101544.
HOVERGENiHBG108220.
InParanoidiQ5XIG2.
PhylomeDBiQ5XIG2.
TreeFamiTF329591.

Family and domain databases

Gene3Di2.60.120.40. 1 hit.
InterProiIPR001073. C1q_dom.
IPR008160. Collagen.
IPR008983. Tumour_necrosis_fac-like_dom.
[Graphical view]
PfamiPF00386. C1q. 1 hit.
PF01391. Collagen. 1 hit.
[Graphical view]
PRINTSiPR00007. COMPLEMNTC1Q.
SMARTiSM00110. C1Q. 1 hit.
[Graphical view]
SUPFAMiSSF49842. SSF49842. 1 hit.
PROSITEiPS50871. C1Q. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5XIG2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSRGQGFML GCCLLLAVTW GPVLSLVPRV QEEQQEWEET EELTSPLDHV
60 70 80 90 100
TRPEETHKRY SPSLREGLPT SRCYRCCDSN PPVYQTIPPP QINITILKGE
110 120 130 140 150
KGDRGDRGLQ GKYGKIGSTG PRGHIGPKGQ KGSMGAPGDH CKSQYAAFSV
160 170 180 190 200
GRKKALHSND YFQPVVFDTE FVNLYNHFNM FTGKFYCYVP GIYFFSLNVH
210 220 230 240 250
TWNQKETYLH IMKNEEEVVI LYAQVSDRSI MQSQSLMLEL REQDEVWVRL
260 270 280
FKGERENAIF SDEFDTYITF SGYLVKPASE P
Length:281
Mass (Da):32,042
Last modified:November 23, 2004 - v1
Checksum:iBDCEF78BA9FC1336
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC083720 mRNA. Translation: AAH83720.1.
RefSeqiNP_001007676.1. NM_001007675.1.
XP_006247863.1. XM_006247801.3.
XP_006247864.1. XM_006247802.3.
XP_017452836.1. XM_017597347.1.
UniGeneiRn.53880.

Genome annotation databases

EnsembliENSRNOT00000004373; ENSRNOP00000004373; ENSRNOG00000003259.
GeneIDi303701.
KEGGirno:303701.
UCSCiRGD:1359204. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC083720 mRNA. Translation: AAH83720.1.
RefSeqiNP_001007676.1. NM_001007675.1.
XP_006247863.1. XM_006247801.3.
XP_006247864.1. XM_006247802.3.
XP_017452836.1. XM_017597347.1.
UniGeneiRn.53880.

3D structure databases

ProteinModelPortaliQ5XIG2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000004373.

Proteomic databases

PaxDbiQ5XIG2.
PRIDEiQ5XIG2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000004373; ENSRNOP00000004373; ENSRNOG00000003259.
GeneIDi303701.
KEGGirno:303701.
UCSCiRGD:1359204. rat.

Organism-specific databases

CTDi114897.
RGDi1359204. C1qtnf1.

Phylogenomic databases

eggNOGiENOG410IKX5. Eukaryota.
ENOG410XQIM. LUCA.
GeneTreeiENSGT00760000118830.
HOGENOMiHOG000101544.
HOVERGENiHBG108220.
InParanoidiQ5XIG2.
PhylomeDBiQ5XIG2.
TreeFamiTF329591.

Miscellaneous databases

PROiQ5XIG2.

Gene expression databases

BgeeiENSRNOG00000003259.
ExpressionAtlasiQ5XIG2. baseline and differential.
GenevisibleiQ5XIG2. RN.

Family and domain databases

Gene3Di2.60.120.40. 1 hit.
InterProiIPR001073. C1q_dom.
IPR008160. Collagen.
IPR008983. Tumour_necrosis_fac-like_dom.
[Graphical view]
PfamiPF00386. C1q. 1 hit.
PF01391. Collagen. 1 hit.
[Graphical view]
PRINTSiPR00007. COMPLEMNTC1Q.
SMARTiSM00110. C1Q. 1 hit.
[Graphical view]
SUPFAMiSSF49842. SSF49842. 1 hit.
PROSITEiPS50871. C1Q. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiC1QT1_RAT
AccessioniPrimary (citable) accession number: Q5XIG2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: November 23, 2004
Last modified: November 30, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.