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Protein

Armadillo repeat-containing X-linked protein 3

Gene

Armcx3

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. cellular protein localization Source: Ensembl
  2. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Armadillo repeat-containing X-linked protein 3
Gene namesi
Name:Armcx3
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494 Componenti: Chromosome X

Organism-specific databases

RGDi1549739. Armcx3.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei7 – 2923HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of mitochondrial outer membrane Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 379379Armadillo repeat-containing X-linked protein 3PRO_0000191369Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei61 – 611PhosphoserineBy similarity
Modified residuei67 – 671PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ5XID7.
PRIDEiQ5XID7.

PTM databases

PhosphoSiteiQ5XID7.

Expressioni

Gene expression databases

GenevestigatoriQ5XID7.

Interactioni

Protein-protein interaction databases

BioGridi266720. 1 interaction.
STRINGi10116.ENSRNOP00000033859.

Structurei

3D structure databases

ProteinModelPortaliQ5XID7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati111 – 15141ARM 1Add
BLAST
Repeati153 – 19240ARM 2Add
BLAST
Repeati233 – 27240ARM 3Add
BLAST

Sequence similaritiesi

Contains 3 ARM repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG303147.
GeneTreeiENSGT00550000074488.
HOGENOMiHOG000231611.
HOVERGENiHBG080349.
InParanoidiQ5XID7.
OMAiCPGARYN.
OrthoDBiEOG70PBZ0.
PhylomeDBiQ5XID7.
TreeFamiTF335652.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR006911. ARM-rpt_dom.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
[Graphical view]
PfamiPF04826. Arm_2. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50176. ARM_REPEAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5XID7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGYARKVGWV TAGLVIGAGA CYCIYRLTRG RKQNKEKMAE GGPGDVEDAG
60 70 80 90 100
DCSGARYNDW SDDDDDSNES KSIVWYPPWA RIGTEAGTRA RARARARATR
110 120 130 140 150
ARRAVQKRAS PNSDDTVLSP QELQKVLCLV EMSEKPYILE AALIALGNNA
160 170 180 190 200
AYAFNRDIIR DLGGLPIVAK ILNTRDPIVK EKALIVLNNL SVNAENQRRL
210 220 230 240 250
KIYMNQVCDD TVTSRLNSSV QLAGLRLLTN MTVTNEYQHI LANSISDFFR
260 270 280 290 300
LFSAGNEETK LQVLKLLLNL AENPAMTREL LGAHVPSSLG SLFNKKEYKE
310 320 330 340 350
VILKLLSIFE NINDNFKWEE NEPAQNHFSE GSLFFFLKEF QVCADKVLGI
360 370
ESHHDFQVRV KVGKFVTKLT ERMFPKSQE
Length:379
Mass (Da):42,553
Last modified:November 22, 2004 - v1
Checksum:iE4EA20CAAF376842
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC083747 mRNA. Translation: AAH83747.1.
RefSeqiNP_001014295.1. NM_001014273.1.
UniGeneiRn.44741.

Genome annotation databases

EnsembliENSRNOT00000029664; ENSRNOP00000033859; ENSRNOG00000025730.
GeneIDi367902.
KEGGirno:367902.
UCSCiRGD:1549739. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC083747 mRNA. Translation: AAH83747.1.
RefSeqiNP_001014295.1. NM_001014273.1.
UniGeneiRn.44741.

3D structure databases

ProteinModelPortaliQ5XID7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi266720. 1 interaction.
STRINGi10116.ENSRNOP00000033859.

PTM databases

PhosphoSiteiQ5XID7.

Proteomic databases

PaxDbiQ5XID7.
PRIDEiQ5XID7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000029664; ENSRNOP00000033859; ENSRNOG00000025730.
GeneIDi367902.
KEGGirno:367902.
UCSCiRGD:1549739. rat.

Organism-specific databases

CTDi51566.
RGDi1549739. Armcx3.

Phylogenomic databases

eggNOGiNOG303147.
GeneTreeiENSGT00550000074488.
HOGENOMiHOG000231611.
HOVERGENiHBG080349.
InParanoidiQ5XID7.
OMAiCPGARYN.
OrthoDBiEOG70PBZ0.
PhylomeDBiQ5XID7.
TreeFamiTF335652.

Miscellaneous databases

NextBioi691822.
PROiQ5XID7.

Gene expression databases

GenevestigatoriQ5XID7.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR006911. ARM-rpt_dom.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
[Graphical view]
PfamiPF04826. Arm_2. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50176. ARM_REPEAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Heart.

Entry informationi

Entry nameiARMX3_RAT
AccessioniPrimary (citable) accession number: Q5XID7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 19, 2005
Last sequence update: November 22, 2004
Last modified: March 3, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.