Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Alanyl-tRNA editing protein Aarsd1

Gene

Aarsd1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala).By similarity

Cofactori

Zn2+CuratedNote: Binds 1 zinc ion per subunit.Curated

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi109 – 1091ZincSequence analysis
Metal bindingi113 – 1131ZincSequence analysis
Metal bindingi209 – 2091ZincSequence analysis
Metal bindingi213 – 2131ZincSequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Alanyl-tRNA editing protein Aarsd1
Alternative name(s):
Alanyl-tRNA synthetase domain-containing protein 1
Gene namesi
Name:Aarsd1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1561650. Aarsd1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 412412Alanyl-tRNA editing protein Aarsd1PRO_0000277467Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei174 – 1741PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ5XI97.
PRIDEiQ5XI97.

PTM databases

PhosphoSiteiQ5XI97.

Expressioni

Gene expression databases

GenevisibleiQ5XI97. RN.

Interactioni

Protein-protein interaction databases

BioGridi565992. 1 interaction.
STRINGi10116.ENSRNOP00000028047.

Structurei

3D structure databases

ProteinModelPortaliQ5XI97.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG2105. Eukaryota.
COG2872. LUCA.
GeneTreeiENSGT00510000046493.
HOGENOMiHOG000230967.
HOVERGENiHBG080017.
InParanoidiQ5XI97.
KOiK07050.
OMAiGQPCDYG.
OrthoDBiEOG71RXJT.
PhylomeDBiQ5XI97.

Family and domain databases

InterProiIPR018165. Ala-tRNA-synth_IIc_core.
IPR018164. Ala-tRNA-synth_IIc_N.
IPR018163. Thr/Ala-tRNA-synth_IIc_edit.
IPR009000. Transl_B-barrel.
IPR012947. tRNA_SAD.
[Graphical view]
PfamiPF01411. tRNA-synt_2c. 1 hit.
PF07973. tRNA_SAD. 1 hit.
[Graphical view]
SMARTiSM00863. tRNA_SAD. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF55186. SSF55186. 1 hit.
PROSITEiPS50860. AA_TRNA_LIGASE_II_ALA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5XI97-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFLCQRDSY AREFTTTVVS CCPAELQTDG NGSKKEVLSG FQVVLEDTLL
60 70 80 90 100
FPEGGGQPDD RGTINDISVL RVTRRGAQAD HFTQTPLSPG SQVQVRVDWE
110 120 130 140 150
RRFDHMQQHS GQHLITAVAD LLFGLKTTSW ELGKLRCVIE LDSPSVTAEQ
160 170 180 190 200
VAAIEQSVNQ KIRDRLPVSV RELSLDDPEV EQVRGRGLPD DHAGPIRVVT
210 220 230 240 250
IEGVDSNMCC GTHVNNLSDL QVIKILGTEK GKKNKSNLIF LAGNRVLKWM
260 270 280 290 300
ERSHGSEKAL TSLLKCGAED HVEAVKKLQN ATKLLQKNNL NLLRDLAVHT
310 320 330 340 350
AHTLRSSPAW GGVVTLHRKE GDSEFMNIIA NEIGSEETLL FLTVGDEKGA
360 370 380 390 400
GLFLLAGPTE AVETLGPRVA EVLEGKGAGK KGRFQGKATK MSRRAEVQAL
410
LQDYVSTQSA EE
Length:412
Mass (Da):45,093
Last modified:November 23, 2004 - v1
Checksum:i5723CBE2109E54C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC083790 mRNA. Translation: AAH83790.1.
RefSeqiNP_001029281.1. NM_001034109.1.
UniGeneiRn.153971.

Genome annotation databases

EnsembliENSRNOT00000028047; ENSRNOP00000028047; ENSRNOG00000020658.
GeneIDi619440.
KEGGirno:619440.
UCSCiRGD:1561650. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC083790 mRNA. Translation: AAH83790.1.
RefSeqiNP_001029281.1. NM_001034109.1.
UniGeneiRn.153971.

3D structure databases

ProteinModelPortaliQ5XI97.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi565992. 1 interaction.
STRINGi10116.ENSRNOP00000028047.

PTM databases

PhosphoSiteiQ5XI97.

Proteomic databases

PaxDbiQ5XI97.
PRIDEiQ5XI97.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000028047; ENSRNOP00000028047; ENSRNOG00000020658.
GeneIDi619440.
KEGGirno:619440.
UCSCiRGD:1561650. rat.

Organism-specific databases

CTDi80755.
RGDi1561650. Aarsd1.

Phylogenomic databases

eggNOGiKOG2105. Eukaryota.
COG2872. LUCA.
GeneTreeiENSGT00510000046493.
HOGENOMiHOG000230967.
HOVERGENiHBG080017.
InParanoidiQ5XI97.
KOiK07050.
OMAiGQPCDYG.
OrthoDBiEOG71RXJT.
PhylomeDBiQ5XI97.

Miscellaneous databases

NextBioi714635.
PROiQ5XI97.

Gene expression databases

GenevisibleiQ5XI97. RN.

Family and domain databases

InterProiIPR018165. Ala-tRNA-synth_IIc_core.
IPR018164. Ala-tRNA-synth_IIc_N.
IPR018163. Thr/Ala-tRNA-synth_IIc_edit.
IPR009000. Transl_B-barrel.
IPR012947. tRNA_SAD.
[Graphical view]
PfamiPF01411. tRNA-synt_2c. 1 hit.
PF07973. tRNA_SAD. 1 hit.
[Graphical view]
SMARTiSM00863. tRNA_SAD. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF55186. SSF55186. 1 hit.
PROSITEiPS50860. AA_TRNA_LIGASE_II_ALA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Kidney.
  2. "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues."
    Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C., Olsen J.V.
    Nat. Commun. 3:876-876(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-174, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiAASD1_RAT
AccessioniPrimary (citable) accession number: Q5XI97
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: November 23, 2004
Last modified: May 11, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.