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Protein

Calicin

Gene

Ccin

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Possible morphogenetic cytoskeletal element in spermiogenic differentiation.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Developmental protein

Keywords - Biological processi

Differentiation, Spermatogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Calicin
Gene namesi
Name:Ccin
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi1359369. Ccin.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 588588CalicinPRO_0000284433Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei149 – 1491PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ5XI58.
PRIDEiQ5XI58.

PTM databases

iPTMnetiQ5XI58.
PhosphoSiteiQ5XI58.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000019887.

Structurei

3D structure databases

ProteinModelPortaliQ5XI58.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini28 – 9871BTBPROSITE-ProRule annotationAdd
BLAST
Domaini133 – 235103BACKAdd
BLAST
Repeati280 – 32748Kelch 1Add
BLAST
Repeati328 – 37548Kelch 2Add
BLAST
Repeati377 – 42347Kelch 3Add
BLAST
Repeati425 – 47551Kelch 4Add
BLAST
Repeati476 – 52550Kelch 5Add
BLAST
Repeati526 – 58055Kelch 6Add
BLAST

Sequence similaritiesi

Contains 1 BTB (POZ) domain.PROSITE-ProRule annotation
Contains 6 Kelch repeats.Curated

Keywords - Domaini

Kelch repeat, Repeat

Phylogenomic databases

eggNOGiKOG4441. Eukaryota.
ENOG410XNX8. LUCA.
GeneTreeiENSGT00800000124141.
HOGENOMiHOG000060293.
HOVERGENiHBG003874.
InParanoidiQ5XI58.
OMAiRCPPVIF.
OrthoDBiEOG7WT40Q.
PhylomeDBiQ5XI58.
TreeFamiTF331981.

Family and domain databases

Gene3Di2.120.10.80. 2 hits.
InterProiIPR011705. BACK.
IPR000210. BTB/POZ_dom.
IPR015915. Kelch-typ_b-propeller.
IPR006652. Kelch_1.
IPR011333. SKP1/BTB/POZ.
[Graphical view]
PfamiPF07707. BACK. 1 hit.
PF00651. BTB. 1 hit.
PF01344. Kelch_1. 1 hit.
[Graphical view]
SMARTiSM00875. BACK. 1 hit.
SM00225. BTB. 1 hit.
SM00612. Kelch. 3 hits.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5XI58-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLEFTEKNY NSFVLQNLNK QRKRKEYWDM ALTVDHHVFF AHRNVLAAVS
60 70 80 90 100
PLVKSLVSSN DMKTTDELYI TIDPNYLSPA TVDQLLDYFY SGKVVISEQN
110 120 130 140 150
VEELLRGAQY FNTPRLRIHC NDFLIKSIRR VNCLRYLFLA ELFELKEVSD
160 170 180 190 200
LAYSGIRDNF HFWASPEGSM HFMRCPPVIF GRLLRDENLH VLNEDQALSA
210 220 230 240 250
LINWVYFRKE EREKYFKKFF NYINLNAVSN KTLMFASNKL TGLENNSAHA
260 270 280 290 300
TLIESVLMDR KQERPCSLLS YQRKGALLDS VVILGGQKAH GKFNDGVFAY
310 320 330 340 350
IIQENLWLKL SEMPYRAAAL SATAAGRYIY ISGGTTEQIS GLKTAWRYDM
360 370 380 390 400
DDNSWTKLPD LPIGLVFHTM VTCGGTVYSV GGSIAPRRYV SNIYRYDERK
410 420 430 440 450
EAWCLAGKMS IPMDGTAVIT KGDRNLYIVT GRCLVKGYIS RVGVVDCFDT
460 470 480 490 500
CTGEVVQCIT FPIEFNHRPL LSFHQDNILR VHSHRQSVEI NLQKIKANKS
510 520 530 540 550
TTSVPLLPNS CPLDVSHAIC SIGDSKVFVC GGVTTASDVQ TKDYTINPNA
560 570 580
YLLDQKIGEW KTLACPPEAL DCPACCLAKL PCKILQRI
Length:588
Mass (Da):66,765
Last modified:November 23, 2004 - v1
Checksum:iEE00F1D2341BFE49
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC083832 mRNA. Translation: AAH83832.1.
RefSeqiNP_001005904.1. NM_001005904.1.
UniGeneiRn.109532.

Genome annotation databases

EnsembliENSRNOT00000019887; ENSRNOP00000019887; ENSRNOG00000014831.
GeneIDi298392.
KEGGirno:298392.
UCSCiRGD:1359369. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC083832 mRNA. Translation: AAH83832.1.
RefSeqiNP_001005904.1. NM_001005904.1.
UniGeneiRn.109532.

3D structure databases

ProteinModelPortaliQ5XI58.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000019887.

PTM databases

iPTMnetiQ5XI58.
PhosphoSiteiQ5XI58.

Proteomic databases

PaxDbiQ5XI58.
PRIDEiQ5XI58.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000019887; ENSRNOP00000019887; ENSRNOG00000014831.
GeneIDi298392.
KEGGirno:298392.
UCSCiRGD:1359369. rat.

Organism-specific databases

CTDi881.
RGDi1359369. Ccin.

Phylogenomic databases

eggNOGiKOG4441. Eukaryota.
ENOG410XNX8. LUCA.
GeneTreeiENSGT00800000124141.
HOGENOMiHOG000060293.
HOVERGENiHBG003874.
InParanoidiQ5XI58.
OMAiRCPPVIF.
OrthoDBiEOG7WT40Q.
PhylomeDBiQ5XI58.
TreeFamiTF331981.

Miscellaneous databases

PROiQ5XI58.

Family and domain databases

Gene3Di2.120.10.80. 2 hits.
InterProiIPR011705. BACK.
IPR000210. BTB/POZ_dom.
IPR015915. Kelch-typ_b-propeller.
IPR006652. Kelch_1.
IPR011333. SKP1/BTB/POZ.
[Graphical view]
PfamiPF07707. BACK. 1 hit.
PF00651. BTB. 1 hit.
PF01344. Kelch_1. 1 hit.
[Graphical view]
SMARTiSM00875. BACK. 1 hit.
SM00225. BTB. 1 hit.
SM00612. Kelch. 3 hits.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.
  2. "Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites."
    Hoffert J.D., Pisitkun T., Wang G., Shen R.-F., Knepper M.A.
    Proc. Natl. Acad. Sci. U.S.A. 103:7159-7164(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-149, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiCALI_RAT
AccessioniPrimary (citable) accession number: Q5XI58
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: November 23, 2004
Last modified: July 6, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.