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Protein

Ecto-ADP-ribosyltransferase 5

Gene

Art5

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

NAD+ + protein-L-arginine = nicotinamide + N(omega)-(ADP-D-ribosyl)-protein-L-arginine.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei100NADBy similarity1
Binding sitei161NADBy similarity1
Binding sitei181NADBy similarity1
Binding sitei215NADBy similarity1
Active sitei229By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
LigandNAD, NADP

Names & Taxonomyi

Protein namesi
Recommended name:
Ecto-ADP-ribosyltransferase 5 (EC:2.4.2.31)
Alternative name(s):
ADP-ribosyltransferase C2 and C3 toxin-like 5
Short name:
ARTC5
Mono(ADP-ribosyl)transferase 5
NAD(P)(+)--arginine ADP-ribosyltransferase 5
Gene namesi
Name:Art5
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi628834 Art5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000037947224 – 308Ecto-ADP-ribosyltransferase 5Add BLAST285

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi43 ↔ 259By similarity
Glycosylationi102N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi197N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi251N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ5XHY4

Expressioni

Gene expression databases

BgeeiENSRNOG00000020242
GenevisibleiQ5XHY4 RN

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000052118

Structurei

3D structure databases

ProteinModelPortaliQ5XHY4
SMRiQ5XHY4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IVE0 Eukaryota
ENOG4111WZG LUCA
GeneTreeiENSGT00530000062975
HOGENOMiHOG000273888
InParanoidiQ5XHY4
KOiK19977
OMAiLHFEPKR
OrthoDBiEOG091G0BSN
PhylomeDBiQ5XHY4

Family and domain databases

InterProiView protein in InterPro
IPR000768 ART
PfamiView protein in Pfam
PF01129 ART, 1 hit
PRINTSiPR00970 RIBTRNSFRASE
PROSITEiView protein in PROSITE
PS01291 ART, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5XHY4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILEDLLMVL SCLALHILWK VQAVPILPLS LVPDTFDDAY VGCSEEMEEK
60 70 80 90 100
AGLLLKEEMA RHALLRESWE AAQEAWAHGR HKLTLPPGFK AQHGVAVMVY
110 120 130 140 150
TNSSNTLYWE LNQAVRTGGR SRELYMRHFP FKALHFYLTR ALQLLRGTGG
160 170 180 190 200
CSREAGEVVF RGVSSLHFEP KRLGDSVRLG QFASSSVDER VARRFGNATF
210 220 230 240 250
FNLRTCFGAP IQALSVFPEE REVLIPPHEV FLVTGFSQDG AQSIVTLWSY
260 270 280 290 300
NQTCSHFNCA YLGGEKRRGC VSSRAGQPES FSTEALALQS GKTLLLAPGE

LQLSRAGP
Length:308
Mass (Da):34,201
Last modified:November 23, 2004 - v1
Checksum:i45B0063435437D2F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC083915 mRNA Translation: AAH83915.1
RefSeqiNP_001013057.1, NM_001013039.1
XP_017444328.1, XM_017588839.1
UniGeneiRn.19845

Genome annotation databases

EnsembliENSRNOT00000055243; ENSRNOP00000052118; ENSRNOG00000020242
GeneIDi259167
KEGGirno:259167
UCSCiRGD:628834 rat

Similar proteinsi

Entry informationi

Entry nameiNAR5_RAT
AccessioniPrimary (citable) accession number: Q5XHY4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 7, 2009
Last sequence update: November 23, 2004
Last modified: May 23, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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