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Protein
Submitted name:

DOCK2 protein

Gene

DOCK2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
DOCK2 proteinImported
Gene namesi
Name:DOCK2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27454.

PTM / Processingi

Proteomic databases

PaxDbiQ5XG91.
PeptideAtlasiQ5XG91.

Expressioni

Gene expression databases

BgeeiQ5XG91.
GenevisibleiQ5XG91. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000256935.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 409409DHR-2InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1998. Eukaryota.
ENOG410XQH7. LUCA.
HOVERGENiHBG102047.
KOiK12367.

Family and domain databases

InterProiIPR027357. DHR-2.
IPR026791. DOCK.
IPR026799. DOCK_2.
IPR010703. DOCK_C.
[Graphical view]
PANTHERiPTHR23317. PTHR23317. 1 hit.
PTHR23317:SF73. PTHR23317:SF73. 1 hit.
PfamiPF06920. DHR-2. 1 hit.
[Graphical view]
PROSITEiPS51651. DHR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q5XG91-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
NNREEMYIRY LYKLRDLHLD CDNYTEAAYT LLLHTWLLKW SDEQCASQVM
60 70 80 90 100
QTGQQHPQTH RQLKETLYET IIGYFDKGKM WEEAISLCKE LAEQYEMEIF
110 120 130 140 150
DYELLSQNLI QQAKFYESIM KILRPKPDYF AVGYYGQGFP SFLRNKVFIY
160 170 180 190 200
RGKEYERRED FQMQLMTQFP NAEKMNTTSA PGDDVKNAPG QYIQCFTVQP
210 220 230 240 250
VLDEHPRFKN KPVPDQIINF YKSNYVQRFH YSRPVRRGTV DPENEFASMW
260 270 280 290 300
IERTSFVTAY KLPGILRWFE VVHMSQTTIS PLENAIETMS TANEKILMMI
310 320 330 340 350
NQYQSDETLP INPLSMLLNG IVDPAVMGGF AKYEKAFFTE EYVRDHPEDQ
360 370 380 390 400
DKLTHLKDLI AWQIPFLGAG IKIHEKRVSD NLRPFHDRME ECFKNLKMKV
410 420 430 440 450
EKEYGVREMP DFDDRRVGRP RSMLRSYRQM SIISLASMNS DCSTPSKPTS
460 470 480 490 500
ESFDLELASP KTPRVEQEEP ISPGSTLPEV KLRRSKKRTK RSSVVFADEK
510 520 530 540 550
AAAESDLKRL SRKHEFMSDT NLSEHAAIPL KASVLSQMSF ASQSMPTIPA
560 570 580 590 600
LALSVAGIPG LDEANTSPRL SQTFLQLSDG DKKTLTRKKV NQFFKTMLAS
610
KSAEEGKQIP DSLSTDL
Length:617
Mass (Da):71,419
Last modified:November 23, 2004 - v1
Checksum:i31CC6C0FE1AEDEF7
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC084556 mRNA. Translation: AAH84556.1.
RefSeqiNP_004937.1. NM_004946.2.
UniGeneiHs.586174.

Genome annotation databases

GeneIDi1794.
KEGGihsa:1794.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC084556 mRNA. Translation: AAH84556.1.
RefSeqiNP_004937.1. NM_004946.2.
UniGeneiHs.586174.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000256935.

Proteomic databases

PaxDbiQ5XG91.
PeptideAtlasiQ5XG91.

Protocols and materials databases

DNASUi1794.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1794.
KEGGihsa:1794.

Organism-specific databases

CTDi1794.
PharmGKBiPA27454.

Phylogenomic databases

eggNOGiKOG1998. Eukaryota.
ENOG410XQH7. LUCA.
HOVERGENiHBG102047.
KOiK12367.

Miscellaneous databases

ChiTaRSiDOCK2. human.
GenomeRNAii1794.

Gene expression databases

BgeeiQ5XG91.
GenevisibleiQ5XG91. HS.

Family and domain databases

InterProiIPR027357. DHR-2.
IPR026791. DOCK.
IPR026799. DOCK_2.
IPR010703. DOCK_C.
[Graphical view]
PANTHERiPTHR23317. PTHR23317. 1 hit.
PTHR23317:SF73. PTHR23317:SF73. 1 hit.
PfamiPF06920. DHR-2. 1 hit.
[Graphical view]
PROSITEiPS51651. DHR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BloodImported.

Entry informationi

Entry nameiQ5XG91_HUMAN
AccessioniPrimary (citable) accession number: Q5XG91
Entry historyi
Integrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: July 6, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.