Q5XC82NADK_STRP6NAD kinase2.7.1.23ATP-dependent NAD kinasenadKM6_Spy0846Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)BacteriaBacillotaBacilliLactobacillalesStreptococcaceaeStreptococcusProgress toward characterization of the group A Streptococcus metagenome: complete genome sequence of a macrolide-resistant serotype M6 strain.NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.ATP + NAD(+) = ADP + H(+) + NADP(+)a divalent metal cationCytoplasmBelongs to the NAD kinase family.Extended N-terminus.ATP-bindingCytoplasmKinaseNADNADPNucleotide-bindingTransferaseNAD(+)NAD(+)NAD(+)NAD(+)NAD(+)MTQMNYTGKVKRVAIIANGKYQSKRVASKLFSVFKDDPDFYLSKKNPDIVISIGGDGMLLSAFHMYEKELDKVRFVGIHTGHLGFYTDYRDFEVDKLIDNLRKDKGEQISYPILKVAITLDDGRVVKARALNEATVKRIEKTMVADVIINHVKFESFRGDGISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSIIIPKKDKIELVPKRLGIYTISIDNKTYQLKNVTKVEYFIDDEKIHFVSSPSHTSFWERVKDAFIGEIDS
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