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Q5XC31

- CITX_STRP6

UniProt

Q5XC31 - CITX_STRP6

Protein

Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferase

Gene

citX

Organism
Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 2 (29 Mar 2005)
      Previous versions | rss
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    Functioni

    Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein.UniRule annotation

    Catalytic activityi

    2'-(5-triphosphoribosyl)-3'-dephospho-CoA + citrate lyase apo-[acyl-carrier-protein] = citrate lyase holo-[acyl-carrier-protein] + diphosphate.UniRule annotation

    GO - Molecular functioni

    1. holo-citrate lyase synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. prosthetic group biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Nucleotidyltransferase, Transferase

    Enzyme and pathway databases

    BioCyciSPYO286636:GHNO-957-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferaseUniRule annotation (EC:2.7.7.61UniRule annotation)
    Alternative name(s):
    Apo-ACP nucleodityltransferaseUniRule annotation
    Holo-ACP synthaseUniRule annotation
    Holo-citrate lyase synthaseUniRule annotation
    Gene namesi
    Name:citXUniRule annotation
    Ordered Locus Names:M6_Spy0897
    OrganismiStreptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)
    Taxonomic identifieri286636 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000001167: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 192192Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferasePRO_0000214690Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi286636.M6_Spy0897.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the CitX family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG3697.
    HOGENOMiHOG000130710.
    KOiK05964.
    OrthoDBiEOG6T7NCD.

    Family and domain databases

    HAMAPiMF_00398. CitX.
    InterProiIPR005551. CitX.
    [Graphical view]
    PfamiPF03802. CitX. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR03124. citrate_citX. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q5XC31-1 [UniParc]FASTAAdd to Basket

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    MSKEAYFSGE SIQLSDMLRA REERALRQLH LLKEYPEGSL LSVTMNIPGP    50
    IKTSPKLLEA FDIVIKAIQT ALADDKICYQ LRLLPTTGYE YYLITSLPSR 100
    DLKLKMIALE TELPIGRLMD LDVLVLQNDL PHSISRTVLG GSPRQCFICS 150
    KEAKVCGRLR KHSVEEMQTA ISKLLHSFFN KDNQSSSSDK TG 192
    Length:192
    Mass (Da):21,602
    Last modified:March 29, 2005 - v2
    Checksum:i709BDF79E23D4831
    GO

    Sequence cautioni

    The sequence AAT87032.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000003 Genomic DNA. Translation: AAT87032.1. Different initiation.
    RefSeqiYP_060215.1. NC_006086.1.

    Genome annotation databases

    EnsemblBacteriaiAAT87032; AAT87032; M6_Spy0897.
    GeneIDi2942547.
    KEGGispa:M6_Spy0897.
    PATRICi19723962. VBIStrPyo30273_0926.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000003 Genomic DNA. Translation: AAT87032.1 . Different initiation.
    RefSeqi YP_060215.1. NC_006086.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 286636.M6_Spy0897.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAT87032 ; AAT87032 ; M6_Spy0897 .
    GeneIDi 2942547.
    KEGGi spa:M6_Spy0897.
    PATRICi 19723962. VBIStrPyo30273_0926.

    Phylogenomic databases

    eggNOGi COG3697.
    HOGENOMi HOG000130710.
    KOi K05964.
    OrthoDBi EOG6T7NCD.

    Enzyme and pathway databases

    BioCyci SPYO286636:GHNO-957-MONOMER.

    Family and domain databases

    HAMAPi MF_00398. CitX.
    InterProi IPR005551. CitX.
    [Graphical view ]
    Pfami PF03802. CitX. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR03124. citrate_citX. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Progress toward characterization of the group A Streptococcus metagenome: complete genome sequence of a macrolide-resistant serotype M6 strain."
      Banks D.J., Porcella S.F., Barbian K.D., Beres S.B., Philips L.E., Voyich J.M., DeLeo F.R., Martin J.M., Somerville G.A., Musser J.M.
      J. Infect. Dis. 190:727-738(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-946 / MGAS10394.

    Entry informationi

    Entry nameiCITX_STRP6
    AccessioniPrimary (citable) accession number: Q5XC31
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 29, 2005
    Last sequence update: March 29, 2005
    Last modified: October 1, 2014
    This is version 54 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3