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Q5X8H6 (YACG_LEGPA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
DNA gyrase inhibitor YacG
Gene names
Name:yacG
Ordered Locus Names:lpp0275
OrganismLegionella pneumophila (strain Paris) [Complete proteome] [HAMAP]
Taxonomic identifier297246 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella

Protein attributes

Sequence length70 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase By similarity. HAMAP-Rule MF_00649

Cofactor

Binds 1 zinc ion By similarity. HAMAP-Rule MF_00649

Subunit structure

Interacts with GyrB By similarity. HAMAP-Rule MF_00649

Sequence similarities

Belongs to the DNA gyrase inhibitor YacG family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7070DNA gyrase inhibitor YacG HAMAP-Rule MF_00649
PRO_0000211703

Sites

Metal binding91Zinc By similarity
Metal binding121Zinc By similarity
Metal binding281Zinc By similarity
Metal binding321Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5X8H6 [UniParc].

Last modified November 23, 2004. Version 1.
Checksum: 05502F6644477617

FASTA708,015
        10         20         30         40         50         60 
MNNQQKIKCP ICGKQNTWSP DNQFRPFCSE RCKLIDLGEW ASESRKIPGS SIDPESIVTS 

        70 
NNKQDNEDEQ 

« Hide

References

[1]"Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity."
Cazalet C., Rusniok C., Brueggemann H., Zidane N., Magnier A., Ma L., Tichit M., Jarraud S., Bouchier C., Vandenesch F., Kunst F., Etienne J., Glaser P., Buchrieser C.
Nat. Genet. 36:1165-1173(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Paris.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR628336 Genomic DNA. Translation: CAH11423.1.
RefSeqYP_122617.1. NC_006368.1.

3D structure databases

ProteinModelPortalQ5X8H6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING297246.lpp0275.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAH11423; CAH11423; lpp0275.
GeneID3119541.
KEGGlpp:lpp0275.
PATRIC22320732. VBILegPne27771_0447.

Organism-specific databases

LegioListlpp0275.
CMRSearch...

Phylogenomic databases

eggNOGCOG3024.
HOGENOMHOG000255917.
KOK09862.
OMAAWANERY.
OrthoDBEOG65F8ZX.

Enzyme and pathway databases

BioCycLPNE297246:GCO9-326-MONOMER.

Family and domain databases

Gene3D3.30.50.10. 1 hit.
HAMAPMF_00649. DNA_gyrase_inhibitor_YacG.
InterProIPR005584. DNA_gyrase_inhibitor_YacG.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamPF03884. DUF329. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYACG_LEGPA
AccessionPrimary (citable) accession number: Q5X8H6
Entry history
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: November 23, 2004
Last modified: May 14, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families