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Protein

tRNA pseudouridine synthase D

Gene

truD

Organism
Legionella pneumophila (strain Paris)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei79 – 791NucleophileUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)
Alternative name(s):
tRNA pseudouridine(13) synthaseUniRule annotation
tRNA pseudouridylate synthase DUniRule annotation
tRNA-uridine isomerase DUniRule annotation
Gene namesi
Name:truDUniRule annotation
Ordered Locus Names:lpp1593
OrganismiLegionella pneumophila (strain Paris)
Taxonomic identifieri297246 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella

Organism-specific databases

LegioListilpp1593.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 338338tRNA pseudouridine synthase DPRO_0000152505Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi297246.lpp1593.

Structurei

3D structure databases

ProteinModelPortaliQ5X4T2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini154 – 303150TRUDUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.UniRule annotation
Contains 1 TRUD domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4106NZV. Bacteria.
COG0585. LUCA.
HOGENOMiHOG000224848.
KOiK06176.
OMAiLWLWVEK.
OrthoDBiPOG091H03KK.

Family and domain databases

HAMAPiMF_01082. TruD. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR001656. PsdUridine_synth_TruD.
IPR020119. PsdUridine_synth_TruD_CS.
IPR011760. PsdUridine_synth_TruD_insert.
[Graphical view]
PANTHERiPTHR13326. PTHR13326. 1 hit.
PfamiPF01142. TruD. 2 hits.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
PROSITEiPS50984. TRUD. 1 hit.
PS01268. UPF0024. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5X4T2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYSLDWPRAY GIPNSIATFK SLPEDFQVNE LFEGQFSGEG EHIVLKIEKR
60 70 80 90 100
GLTTEEVVKS LARLINKPVK LISHAGLKDK QALTTQWLSV HAPGEIIDGI
110 120 130 140 150
ETLEAPGWRI LECTRHNKKL KPGFLSGNHF IITLRNVSDE SDLIHRIEQI
160 170 180 190 200
KFKGVPNYFG EQRFGRDGGN LIKAEEILVQ GRKVKDRFLK GMYFSAARSW
210 220 230 240 250
LYNLILSRRV KESSWNLPLL GDVIQLVGSN SIFVNDKSMD EQLLQRIGEK
260 270 280 290 300
DVSPASPLPG RSKNLVKGTA LQIINDVYEE WSAWLDGLEK NGLEEAWRAN
310 320 330
ILYAEQIEYR INQGTVELSF VLPAGAYATV VLRELVQY
Length:338
Mass (Da):38,295
Last modified:November 23, 2004 - v1
Checksum:i788827514EB2EDB9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR628336 Genomic DNA. Translation: CAH12744.1.
RefSeqiWP_011213904.1. NC_006368.1.

Genome annotation databases

EnsemblBacteriaiCAH12744; CAH12744; lpp1593.
KEGGilpp:lpp1593.
PATRICi22323590. VBILegPne27771_1851.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR628336 Genomic DNA. Translation: CAH12744.1.
RefSeqiWP_011213904.1. NC_006368.1.

3D structure databases

ProteinModelPortaliQ5X4T2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi297246.lpp1593.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAH12744; CAH12744; lpp1593.
KEGGilpp:lpp1593.
PATRICi22323590. VBILegPne27771_1851.

Organism-specific databases

LegioListilpp1593.

Phylogenomic databases

eggNOGiENOG4106NZV. Bacteria.
COG0585. LUCA.
HOGENOMiHOG000224848.
KOiK06176.
OMAiLWLWVEK.
OrthoDBiPOG091H03KK.

Family and domain databases

HAMAPiMF_01082. TruD. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR001656. PsdUridine_synth_TruD.
IPR020119. PsdUridine_synth_TruD_CS.
IPR011760. PsdUridine_synth_TruD_insert.
[Graphical view]
PANTHERiPTHR13326. PTHR13326. 1 hit.
PfamiPF01142. TruD. 2 hits.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
PROSITEiPS50984. TRUD. 1 hit.
PS01268. UPF0024. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTRUD_LEGPA
AccessioniPrimary (citable) accession number: Q5X4T2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: November 23, 2004
Last modified: September 7, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.