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Protein

Elongation factor Tu

Gene

tuf1

more
Organism
Legionella pneumophila (strain Lens)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPUniRule annotation8
Nucleotide bindingi81 – 85GTPUniRule annotation5
Nucleotide bindingi136 – 139GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis
LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tuf1UniRule annotation
Ordered Locus Names:lpl0355
AND
Name:tuf2UniRule annotation
Ordered Locus Names:lpl0367
OrganismiLegionella pneumophila (strain Lens)
Taxonomic identifieri297245 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella
Proteomesi
  • UP000002517 Componenti: Chromosome

Organism-specific databases

LegioListilpl0355.
lpl0367.

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003374221 – 396Elongation factor TuAdd BLAST396

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ5WZL4.
SMRiQ5WZL4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 206tr-type GAdd BLAST197

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni19 – 26G1By similarity8
Regioni60 – 64G2By similarity5
Regioni81 – 84G3By similarity4
Regioni136 – 139G4By similarity4
Regioni174 – 176G5By similarity3

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000229290.
KOiK02358.
OMAiYGHIDCP.

Family and domain databases

CDDicd03697. EFTU_II. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B. 1 hit.
InterProiView protein in InterPro
IPR004161. EFTu-like_2.
IPR033720. EFTU_2.
IPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel_sf.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
PfamiView protein in Pfam
PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5WZL4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKEKFERKK PHVNVGTIGH VDHGKTTLTA AITTIMAKKY GGTAKAYDQI
60 70 80 90 100
DAAPEERERG ITISTAHVEY ESASRHYAHV DCPGHADYVK NMITGAAQMD
110 120 130 140 150
GAILVVSAAD GPMPQTREHI LLSRQVGVPY IVVFMNKADM VDDPELLELV
160 170 180 190 200
EMEVRDLLSS YDFPGDDIPI IVGSALKALE GEDSDIGVKA IEKLVETMDS
210 220 230 240 250
YIPEPVRNID KPFLLPIEDV FSISGRGTVV TGRVESGIVK VGEEVEIVGI
260 270 280 290 300
RDTQKTTCTG VEMFRKLLDE GRAGDNVGVL LRGTKRDEVE RGQVLAKPGT
310 320 330 340 350
IKPHTKFEAE VYVLSKEEGG RHTPFFNGYR PQFYFRTTDV TGTCDLPSGV
360 370 380 390
EMVMPGDNVQ LVVSLHAPIA MDEGLRFAIR EGGRTVGAGV VAKIIE
Length:396
Mass (Da):43,193
Last modified:November 23, 2004 - v1
Checksum:i8069FEDB74B131C9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR628337 Genomic DNA. Translation: CAH14586.1.
CR628337 Genomic DNA. Translation: CAH14598.1.
RefSeqiWP_011214618.1. NC_006369.1.

Genome annotation databases

EnsemblBacteriaiCAH14586; CAH14586; lpl0355.
CAH14598; CAH14598; lpl0367.
KEGGilpf:lpl0355.
lpf:lpl0367.

Similar proteinsi

Entry informationi

Entry nameiEFTU_LEGPL
AccessioniPrimary (citable) accession number: Q5WZL4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: November 23, 2004
Last modified: November 22, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families