Q5WZC3 (Q5WZC3_LEGPL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Glucose-6-phosphate 1-dehydrogenase RuleBase RU000497
EC=1.1.1.49 RuleBase RU000497

Gene names

Name:	zwf EMBL CAH14689.1
Ordered Locus Names:	lpl0459

Organism

Legionella pneumophila (strain Lens) [Complete proteome] [HAMAP]

Taxonomic identifier

297245 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Legionellaceae › Legionella

Protein attributes

Sequence length	496 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH. RuleBase RU000497
Pathway	Carbohydrate degradation; pentose phosphate pathway. RuleBase RU000497
Sequence similarities	Belongs to the glucose-6-phosphate dehydrogenase family. RuleBase RU000497

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism RuleBase RU000497
Ligand	NADP RuleBase RU000497
Molecular function	Oxidoreductase RuleBase RU000497
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro glucose-6-phosphate dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5WZC3 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: E7036678A7F03DCE	FASTA	496	57,282
	10 20 30 40 50 60 MLLKAESKYP CDLILFGTLG DLSCRKLLPA LYQLELANLL HEKTRIIGCA REELDFSAYV 70 80 90 100 110 120 DLIKNKIQQF LFDEIDEAVW LRFVKKLAYC KLDLNQSDDY QKLTDYVNPS ERVVISYLAI 130 140 150 160 170 180 PPSLYSQTCR SLARLNLTQK PSRVVLEKPI GHDLPSSVAT NEQVACFFAE DQIYRIDHYL 190 200 210 220 230 240 GKETVLNLLV LRFANSIFST NWDNRVIDRV EISVAEEIGV EGRWEYYDKS GQVRDMLQNH 250 260 270 280 290 300 LLQILSLVAM EPPLSLSAES IRSEKLKVLK SLRFINKSNV HDHTVRAQYV ANTLANGKKI 310 320 330 340 350 360 PGYLEEVGAN QASTTETFVA IKAYVDNWRW SGVPFYMLTG KRLPKKQSEV VIYFKPQPYN 370 380 390 400 410 420 IFHPLNEELY PNQLIIRLQP DEGVEVRIMN KIPGLGERMM LHDSKLDLNF HHSFKTQRIA 430 440 450 460 470 480 DAYERLLLEV MLGNQYLFVS REEIEQAWQW IDSIVSAWEE DNIPLYTYPA CTWGPKEVIR 490 LFNGQAHVWG DHNAVS

References

[1]

"Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity." Cazalet C., Rusniok C., Brueggemann H., Zidane N., Magnier A., Ma L., Tichit M., Jarraud S., Bouchier C., Vandenesch F., Kunst F., Etienne J., Glaser P., Buchrieser C. Nat. Genet. 36:1165-1173(2004) [PubMed: 15467720] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR628337 Genomic DNA. Translation: CAH14689.1.
RefSeq	YP_125825.1. NC_006369.1.
3D structure databases
ProteinModelPortal	Q5WZC3.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5WZC3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3116277.
GenomeReviews	Gene locus lpl0459 in contig CR628337_GR.
KEGG	lpf:lpl0459.
NMPDR	fig|297245.3.peg.668.
PATRIC	22314415. VBILegPne33733_0549.
Organism-specific databases
LegioList	lpl0459.
CMR	Search...
Phylogenomic databases
eggNOG	COG0364.
HOGENOM	HBG322449.
OMA	DNIYENT.
PhylomeDB	Q5WZC3.
ProtClustDB	PRK05722.
Family and domain databases
InterPro	IPR001282. G6P_DH. IPR019796. G6P_DH_AS. IPR022675. G6P_DH_C. IPR022674. G6P_DH_NAD-bd. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00036.
PANTHER	PTHR23429. G6PDH. 1 hit.
Pfam	PF02781. G6PD_C. 1 hit. PF00479. G6PD_N. 1 hit. [Graphical view]
PIRSF	PIRSF000110. G6PD. 1 hit.
PRINTS	PR00079. G6PDHDRGNASE.
TIGRFAMs	TIGR00871. Zwf. 1 hit.
PROSITE	PS00069. G6P_DEHYDROGENASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5WZC3_LEGPL

Accession

Primary (citable) accession number: Q5WZC3

Entry history

Integrated into UniProtKB/TrEMBL:	November 23, 2004
Last sequence update:	November 23, 2004
Last modified:	December 14, 2011
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)