Q5WVX6 (GLND_LEGPL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:	glnD
Ordered Locus Names:	lpl1684

Organism

Legionella pneumophila (strain Lens) [Complete proteome] [HAMAP]

Taxonomic identifier

297245 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Legionellaceae › Legionella

Protein attributes

Sequence length	861 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein By similarity. HAMAP MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP MF_00277
Sequence similarities	Belongs to the glnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 861	861	[Protein-PII] uridylyltransferase HAMAP MF_00277		PRO_0000192740

Sequences

	Sequence		Length	Mass (Da)
	Q5WVX6 [UniParc]. Last modified November 23, 2004. Version 1. Checksum: 4D1AB5D391DCE105	FASTA	861	100,671
	10 20 30 40 50 60 MKNDNRIIKN TIKQFKEKLC RDFSQKANIT SITRKLAVFI DTILIQLFIK NKLHFGDNFC 70 80 90 100 110 120 LLALGSYGRR ELQLHSDIDL LILHTEKVSN IQLQRAQKFI QDCWDVGLEV SHQITTVSSC 130 140 150 160 170 180 ANLASQDLSV ISTIMDMFLL CGHGALMEEL IYQTHTLHMW PSHQYFFAKL QEQQSRYAKY 190 200 210 220 230 240 GETAYNLEPN IKNGPGGLRD LQILLSISKR HFKIKKLAEG IGYGFITDKE YEELKYCQNF 250 260 270 280 290 300 LWRVRFALHM LAGKPEERLS FDYQVKLAQF FGYQDQSHIL AIEQFMKDYF KVIKRNRELN 310 320 330 340 350 360 EMLLQWFNET IVYHQKQKII RLDDEFQLSN RFIEVRNNRV FKQNPQSILK LFYWLVKRPD 370 380 390 400 410 420 IEGVRASTIR LIRESLFLMG KRFRESKETA NIFVNIFRTG NDPYDALQRM NRYGVLAHYL 430 440 450 460 470 480 DCFATVTGQM QYDLFHAYTV DQHTLFVIRN ISRFKKNEYA KQFPLCAKII TALEKPEILY 490 500 510 520 530 540 LGALFHDIAK GRGGDHSELG AIEAQQFTQR HYMEAEDSKL IVWLVRYHLL MSQTAQRKDI 550 560 570 580 590 600 YDPKTIEQFC QLLPHAKYLD YLYLLTVADI CGTNPTLWNA WKDSLLKELY HAAKTRLHKQ 610 620 630 640 650 660 QELLDEAALI SIRKQYAMDI LISDGISSRV IQDLWSQFKG KYFLHESPEV IARHTKAILN 670 680 690 700 710 720 SKQFPVVIIM PHHSQGGTEV FIYMPHKDER FTITTSVLSN HHVTIQEAAI ITCDNQFDLD 730 740 750 760 770 780 TYIILDENNQ AFLNEQRARD IQKSLCDHLA NTGRLPAVSR RRLSRALTHF NVKTQINFID 790 800 810 820 830 840 DNTNHQTQLF LVTNDRPGLL ATISRVFLTL NIHLHNAKIA TAGERVEDMF YISNQTGYSL 850 860 NHEEKTILKE KLILEISKSK Y

References

[1]

"Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity." Cazalet C., Rusniok C., Brueggemann H., Zidane N., Magnier A., Ma L., Tichit M., Jarraud S., Bouchier C., Vandenesch F., Kunst F., Etienne J., Glaser P., Buchrieser C. Nat. Genet. 36:1165-1173(2004) [PubMed: 15467720] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Lens.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR628337 Genomic DNA. Translation: CAH15924.1.
RefSeq	YP_127023.1. NC_006369.1.
3D structure databases
ProteinModelPortal	Q5WVX6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5WVX6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3113365.
GenomeReviews	Gene locus lpl1684 in contig CR628337_GR.
KEGG	lpf:lpl1684.
NMPDR	fig|297245.3.peg.1866.
PATRIC	22317079. VBILegPne33733_1866.
Organism-specific databases
LegioList	lpl1684.
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HBG687872.
OMA	MQHDLFH.
PhylomeDB	Q5WVX6.
ProtClustDB	CLSK832981.
Enzyme and pathway databases
BioCyc	LPNE297245:LPL1684-MONOMER.
Family and domain databases
HAMAP	MF_00277. PII_uridylyl-transf. [Tree]
InterPro	IPR010043. GlnD_Uridyltrans. IPR005105. GlnD_Uridyltrans_N. IPR023279. HD. IPR003607. Metal-dep_PHydrolase_HD_dom. IPR006674. Metal-dep_PHydrolase_HD_sub. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
Gene3D	G3DSA:1.10.3210.10. HD. 1 hit.
KO	K00990.
PANTHER	PTHR13734:SF1. GlnD_Uridyltrans. 1 hit.
Pfam	PF03445. DUF294. 1 hit. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_LEGPL

Accession

Primary (citable) accession number: Q5WVX6

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2005
Last sequence update:	November 23, 2004
Last modified:	January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program